| Schedule of significant expense categories |
| | | | | | | | | Years Ended December 31, | | | 2025 | | 2024 | Operating Expenses: | | | | | | | PMN310 development program costs | | $ | 30,226,059 | | $ | 8,275,268 | Other non-employee research and development costs | | | 885,907 | | | 772,501 | Employee costs | | | 5,051,277 | | | 3,336,580 | Other general and administrative costs | | | 4,004,065 | | | 4,443,129 | Net Operating Loss: | | $ | 40,167,308 | | $ | 16,827,478 | Other segment items(a) | | | (448,161) | | | (19,606,351) | Net Loss (Income): | | $ | 39,719,147 | | $ | (2,778,873) | | | | | | | | Reconciliation of Profit or Loss | | | | | | | Adjustments and reconciling items | | | — | | | — | Consolidated Net Loss (Income): | | $ | 39,719,147 | | $ | (2,778,873) | | | | | | | | (a)Other segment items included in segment loss include changes in warrant liability, interest income, and interest expense |
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