v3.26.1
Income Taxes - Narrative (Details) - USD ($)
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Tax Credit Carryforward [Line Items]    
Effective income tax rate $ 0 $ 0
Increases recorded to income tax provision 24,804,000 16,046,000
Unrecognized tax benefits that would impact effective tax rate 4,800,000 3,400,000
Domestic Tax Jurisdiction    
Tax Credit Carryforward [Line Items]    
Effective income tax rate 0 0
Operating loss carryforwards 372,200,000 319,800,000
Domestic Tax Jurisdiction | Subject To Expiration    
Tax Credit Carryforward [Line Items]    
Operating loss carryforwards 2,300,000  
Domestic Tax Jurisdiction | Carried Forward Indefinitely    
Tax Credit Carryforward [Line Items]    
Operating loss carryforwards 369,900,000  
Domestic Tax Jurisdiction | Research Tax Credit Carryforward    
Tax Credit Carryforward [Line Items]    
Tax credit carryforward, amount $ 8,500,000 7,900,000
Domestic Tax Jurisdiction | Research Tax Credit Carryforward | Minimum    
Tax Credit Carryforward [Line Items]    
Costs were required to be amortized for tax purposes 5 years  
Domestic Tax Jurisdiction | Research Tax Credit Carryforward | Maximum    
Tax Credit Carryforward [Line Items]    
Costs were required to be amortized for tax purposes 15 years  
Domestic Tax Jurisdiction | Federal Orphan Drug Tax Credit Carryforward    
Tax Credit Carryforward [Line Items]    
Tax credit carryforward, amount $ 10,000,000.0  
State and Local Jurisdiction    
Tax Credit Carryforward [Line Items]    
Effective income tax rate 0 0
Operating loss carryforwards 43,500,000 $ 39,600,000
State and Local Jurisdiction | Subject To Expiration    
Tax Credit Carryforward [Line Items]    
Operating loss carryforwards 40,500,000  
State and Local Jurisdiction | Carried Forward Indefinitely    
Tax Credit Carryforward [Line Items]    
Operating loss carryforwards 3,000,000.0  
State and Local Jurisdiction | Research Tax Credit Carryforward    
Tax Credit Carryforward [Line Items]    
Tax credit carryforward, amount $ 400,000