Income Taxes (Tables)
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12 Months Ended |
Dec. 31, 2025 |
| Income Tax Disclosure [Abstract] |
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| Income before Income Tax, Domestic and Foreign |
Income (loss) before provision for income taxes consisted of the following (in thousands): | | | | | | | | | | | | | | | | | Year Ended December 31, | | | 2025 | | 2024 | | United States | | $ | (90,351) | | | $ | (75,144) | | | Loss before provision for income taxes | | $ | (90,351) | | | $ | (75,144) | |
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| Effective Income Tax Rate Reconciliation |
The reconciliation of the Company’s statutory tax rate and effective income tax rate is as follows (in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | Year Ended December 31, | | 2025 | | 2024 | | Amount | | Percent | | Amount | | Percent | | US Federal Statutory Tax Rate | $ | (18,974) | | | 21.0 | % | | $ | (15,781) | | | 21.0 | % | | Tax Credits: | | | | | | | | | Research and development credit | (7,288) | | | 8.1 | % | | (3,765) | | | 5.0 | % | | Change in valuation allowance | 24,008 | | | (26.6) | % | | 15,206 | | | (20.2) | % | | Nontaxable or Nondeductible Items: | | | | | | | | | Equity Compensation | 704 | | | (0.8) | % | | 3,242 | | | (4.3) | % | | Other | 92 | | | (0.1) | % | | 345 | | | (0.5) | % | | Changes in Unrecognized Tax Benefits | 1,458 | | | (1.6) | % | | 753 | | | (1.0) | % | | Effective income tax rate | $ | — | | —% | | $ | — | | —% |
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| Deferred Tax Assets and Liabilities |
Significant components of the Company’s net deferred tax assets are as follows (in thousands): | | | | | | | | | | | | | Year Ended December 31, | | 2025 | | 2024 | | Deferred tax assets: | | | | | Net operating loss carryforwards | $ | 80,368 | | | $ | 69,308 | | | Research and development credits | 18,861 | | | 12,840 | | | Accruals & reserves | 1,071 | | | 901 | | | Stock compensation | 3,269 | | | 1,198 | | | Amortization | 716 | | | 768 | | | Lease liability | 2,132 | | | 2,648 | | | Capitalized research and development expenses | 33,861 | | | 28,023 | | | Depreciation | 70 | | | — | | | Total deferred tax assets | 140,348 | | | 115,686 | | | Valuation allowance | (139,776) | | | (114,972) | | | Net deferred tax assets | 572 | | | 714 | | | | | | | Deferred tax liabilities: | | | | | Depreciation | — | | | (71) | | | Right of use asset | (572) | | | (643) | | | Total deferred tax liabilities | (572) | | | (714) | | | Net deferred taxes | $ | — | | | $ | — | |
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| Valuation Allowance |
The Company’s valuation allowance for the years ended December 31, 2025 and 2024 is as follows (in thousands): | | | | | | | | | | | | | | | | | Year Ended December 31, | | | 2025 | | 2024 | | Valuation allowance beginning of year | | $ | 114,972 | | | $ | 98,926 | | | Increases recorded to income tax provision | | 24,804 | | | 16,046 | | | Valuation allowance at end of year | | $ | 139,776 | | | $ | 114,972 | |
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| Unrecognized Tax Benefits Roll Forward |
A reconciliation of the beginning and ending amount of unrecognized tax benefits is as follows (in thousands): | | | | | | | | | | | | | Year Ended December 31, | | 2025 | | 2024 | | Beginning balance | $ | 3,364 | | | $ | 2,611 | | | Additions based on tax positions related to current year | 1,138 | | | 654 | | | Additions for tax positions of prior years | 320 | | | 99 | | | Ending Balance | $ | 4,822 | | | $ | 3,364 | |
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