v3.26.1
Consolidated Statements of Shareholders’ (Deficit) Equity - USD ($)
$ in Thousands
Total
Ordinary shares
At-The-Market Offering
ORDINARY SHARES
Ordinary shares
ORDINARY SHARES
At-The-Market Offering
Ordinary shares
ADDITIONAL PAID-IN CAPITAL
ADDITIONAL PAID-IN CAPITAL
At-The-Market Offering
ACCUMULATED OTHER COMPREHENSIVE (LOSS)/INCOME
ACCUMULATED DEFICIT
Beginning balance (in shares) at Dec. 31, 2023       61,943,471          
Beginning balance at Dec. 31, 2023 $ 225,744     $ 635   $ 621,645   $ (16,926) $ (379,610)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Issuance of ordinary shares, net of issuance costs (in shares)         2,509,798        
Issuance of ordinary shares, net of issuance costs     $ 26,219   $ 25   $ 26,194    
Issuance of warrants to purchase ordinary shares (in shares)       3,752,050          
Issuance of warrants to purchase ordinary shares 37,258     $ 38   37,220      
Exercise of share options (in shares)   189,214   189,214          
Exercise of share options 221     $ 2   219      
Issuance of ordinary shares to settle vested restricted stock units (in shares)   83,527   83,527          
Issuance of ordinary shares to settle vested restricted stock units 0     $ 1   (1)      
Issuance of ordinary shares under employee share purchase plan (in shares)       74,155          
Issuance of ordinary shares under employee share purchase plan 365     $ 1   364      
Shares tendered for withholding taxes (239)         (239)      
Share-based compensation expense 19,517         19,517      
Unrealized gain on foreign currency translation 732             732  
Net loss $ (155,122)               (155,122)
Ending balance (in shares) at Dec. 31, 2024 68,552,215     68,552,215          
Ending balance at Dec. 31, 2024 $ 154,695     $ 702   704,919   (16,194) (534,732)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Issuance of ordinary shares, net of issuance costs (in shares)       24,014,728          
Issuance of ordinary shares, net of issuance costs 54,817     $ 233   54,584      
Issuance of warrants to purchase ordinary shares (in shares)       2,344,666          
Issuance of warrants to purchase ordinary shares $ 10,152     $ 25   10,127      
Exercise of share options (in shares) 925,179 925,179   925,179          
Exercise of share options $ 35     $ 10   25      
Issuance of ordinary shares to settle vested restricted stock units (in shares)   156,245   156,245          
Issuance of ordinary shares to settle vested restricted stock units 1     $ 2   (1)      
Issuance of ordinary shares under employee share purchase plan (in shares)       92,752          
Issuance of ordinary shares under employee share purchase plan 319     $ 1   318      
Share-based compensation expense 13,590         13,590      
Unrealized gain on foreign currency translation 1,405             1,405  
Net loss $ (287,862)               (287,862)
Ending balance (in shares) at Dec. 31, 2025 96,085,785     96,085,785          
Ending balance at Dec. 31, 2025 $ (52,848)     $ 973   $ 783,562   $ (14,789) $ (822,594)