v3.26.1
Note 14 - Income Taxes (Tables)
12 Months Ended
Dec. 31, 2025
Notes Tables  
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
   

December 31,
2025

   

December 31,
2024

 

Deferred tax assets:

               

Accruals and other

  $ 1,854     $ 1,347  

Research credits

    3,006       8,379  

Net operating loss carryforward

    63,733       90,142  

Section 59(e) R&D expenditures

    2,763       1,136  

Section 174 R&D expenditures

    1,780       2,446  

XOMA royalty

    1,819       1,371  

Total deferred tax assets

    74,955       104,821  

Deferred tax liabilities:

               

IP from acquisition

    (2,468 )     (1,852 )

Total deferred tax liabilities

    (2,468 )     (1,852 )

Valuation allowance

    (72,487 )     (102,969 )

Net deferred tax assets

  $     $  
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
   

Year Ended December 31, 2025

 
   

Amount

    Percent  

Tax at statutory federal rate

  $ (3,001 )     21 %

State tax—net of federal benefit

    -       0 %

Research credits

    (93 )     1 %

Stock options

    266       (2 )%

Other

    (89 )     1 %

Change in valuation allowance

    (24,439 )     171 %

Revaluation of put option liability

    276       (2 )%

Expiration of NOL’s/credits due to ownership change

    27,080       (190 )%

Provision for income taxes

  $ -       0 %
   

Year Ended

December 31, 2024

 

Tax at statutory federal rate

  $ (2,731 )

State tax—net of federal benefit

    55  

Research credits

    (363 )

Stock options

    319  

Other

    10  

Change in valuation allowance

    2,860  

Revaluation of put option liability

    (150 )

Expiration of NOL’s/credits due to ownership change

     

Provision for income taxes

  $  
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
   

Year Ended December 31,

 
   

2025

    2024  

Unrecognized benefit—beginning of period

  $ 3,031     $ 2,835  

Gross decrease—NOL’s/credits limitation

    (1,753 )      

Gross increases—current period tax positions

    97       196  

Unrecognized benefit—end of period

  $ 1,375     $ 3,031