v3.26.1
Document And Entity Information - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2025
Mar. 18, 2026
Jun. 30, 2025
Document Information [Line Items]      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2025    
Document Transition Report false    
Entity File Number 001-35068    
Entity Registrant Name TALPHERA, INC.    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 41-2193603    
Entity Address, Address Line One 1850 Gateway Drive, Suite 175    
Entity Address, City or Town San Mateo    
Entity Address, State or Province CA    
Entity Address, Postal Zip Code 94404    
City Area Code 650    
Local Phone Number 216-3500    
Title of 12(b) Security Common Stock, $0.001 par value    
Trading Symbol TLPH    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag false    
Document Financial Statement Error Correction [Flag] false    
Entity Shell Company false    
Entity Public Float     $ 8.3
Entity Common Stock, Shares Outstanding (in shares)   50,049,824  
Auditor Firm ID 207    
Auditor Name BPM LLP    
Auditor Location Walnut Creek, California    
Entity Central Index Key 0001427925    
Current Fiscal Year End Date --12-31    
Document Fiscal Year Focus 2025    
Document Fiscal Period Focus FY    
Amendment Flag false