Income Taxes - Schedule of Components of Deferred Tax Assets (Details) - USD ($) $ in Thousands |
Dec. 31, 2025 |
Dec. 31, 2024 |
|---|---|---|
| Deferred tax assets: | ||
| Net operating loss carryforwards | $ 87,270 | $ 39,662 |
| Research and development credits | 51,991 | 46,739 |
| Capitalized research and development expenditure | 71,492 | 77,845 |
| Deferred royalty obligation | 46,390 | 38,639 |
| Deferred revenue | 2,590 | 16,620 |
| Operating lease liability | 3,312 | 4,948 |
| Stock based compensation | 4,614 | 5,824 |
| Accruals and other | 6,864 | 1,376 |
| Fixed asset basis | 375 | 0 |
| Total deferred tax assets | 274,898 | 231,653 |
| Less: valuation allowance | (272,196) | (227,831) |
| Gross deferred tax assets | 2,702 | 3,822 |
| Deferred tax liabilities: | ||
| Operating lease right-of-use asset | (2,304) | (3,778) |
| Fixed asset basis | 0 | (10) |
| Other | (398) | (34) |
| Total deferred tax liabilities | (2,702) | (3,822) |
| Total net deferred tax assets | $ 0 | $ 0 |
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- Definition Deferred tax assets deferred royalty obligation. No definition available.
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- Definition Deferred tax assets fixed assets. No definition available.
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- Definition Deferred tax assets operating lease liability. No definition available.
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- Definition Deferred tax liabilities fixed assets. No definition available.
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- Definition Deferred tax liabilities operating lease right of use asset. No definition available.
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from deferred income. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount, before allocation of valuation allowance, of deferred tax asset attributable to deductible temporary difference from in-process research and development cost acquired in business combination or from joint venture formation or both. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount, after allocation of valuation allowances and deferred tax liability, of deferred tax asset attributable to deductible differences and carryforwards, without jurisdictional netting. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount after allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- References No definition available.
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible research tax credit carryforwards. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from share-based compensation. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from reserves and accruals. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount, after deferred tax asset, of deferred tax liability attributable to taxable differences without jurisdictional netting. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- References No definition available.
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- Definition Amount of deferred tax liability attributable to taxable temporary differences classified as other. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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