000 - Document - Document And Entity Information link:calculationLink link:definitionLink link:presentationLink 001 - Statement - Consolidated Balance Sheets link:calculationLink link:definitionLink link:presentationLink 002 - Statement - Consolidated Balance Sheets (Parentheticals) link:calculationLink link:definitionLink link:presentationLink 003 - Statement - Consolidated Statements of Operations link:calculationLink link:definitionLink link:presentationLink 004 - Statement - Consolidated Statements of Stockholders' (Deficit) Equity link:calculationLink link:definitionLink link:presentationLink 005 - Statement - Consolidated Statements of Stockholders' (Deficit) Equity (Parentheticals) link:calculationLink link:definitionLink link:presentationLink 006 - Statement - Consolidated Statements of Cash Flows link:calculationLink link:definitionLink link:presentationLink 007 - Statement - Consolidated Statements of Cash Flows link:calculationLink link:definitionLink link:presentationLink 008 - Statement - Consolidated Statements of Cash Flows link:calculationLink link:definitionLink link:presentationLink 995550 - Disclosure - Note 1 - Organization link:calculationLink link:definitionLink link:presentationLink 995551 - Disclosure - Note 2 - Summary of Significant Accounting Policies link:calculationLink link:definitionLink link:presentationLink 995552 - Disclosure - Note 3 - Fair Value Measurements link:calculationLink link:definitionLink link:presentationLink 995553 - Disclosure - Note 4 - Prepaid Expenses and Other Current Assets link:calculationLink link:definitionLink link:presentationLink 995554 - Disclosure - Note 5 - Accrued Liabilities link:calculationLink link:definitionLink link:presentationLink 995555 - Disclosure - Note 6 - Commitments and Contingencies link:calculationLink link:definitionLink link:presentationLink 995556 - Disclosure - Note 7 - Financing Activities link:calculationLink link:definitionLink link:presentationLink 995557 - Disclosure - Note 8 - Convertible Notes link:calculationLink link:definitionLink link:presentationLink 995558 - Disclosure - Note 9 - Common Stock Warrants and Warrant Liabilities link:calculationLink link:definitionLink link:presentationLink 995559 - Disclosure - Note 10 - Stockholders' Deficit link:calculationLink link:definitionLink link:presentationLink 995560 - Disclosure - Note 11 - Stock-based Compensation link:calculationLink link:definitionLink link:presentationLink 995561 - Disclosure - Note 12 - Employee Benefit Plan link:calculationLink link:definitionLink link:presentationLink 995562 - Disclosure - Note 13 - Avenova Asset Divestiture and Bridge Loan link:calculationLink link:definitionLink link:presentationLink 995563 - Disclosure - Note 14 - Phaseone Divestiture link:calculationLink link:definitionLink link:presentationLink 995564 - Disclosure - Note 15 - Dermadoctor Divestiture link:calculationLink link:definitionLink link:presentationLink 995565 - Disclosure - Note 16 - Summary of Discontinued Operations link:calculationLink link:definitionLink link:presentationLink 995566 - Disclosure - Note 17 - Income Taxes link:calculationLink link:definitionLink link:presentationLink 995567 - Disclosure - Note 18 - Related Party Transactions link:calculationLink link:definitionLink link:presentationLink 995568 - Disclosure - Note 19 - Subsequent Events link:calculationLink link:definitionLink link:presentationLink 995569 - Disclosure - Significant Accounting Policies (Policies) link:calculationLink link:definitionLink link:presentationLink 995570 - Disclosure - Note 2 - Summary of Significant Accounting Policies (Tables) link:calculationLink link:definitionLink link:presentationLink 995571 - Disclosure - Note 3 - Fair Value Measurements (Tables) link:calculationLink link:definitionLink link:presentationLink 995572 - Disclosure - Note 4 - Prepaid Expenses and Other Current Assets (Tables) link:calculationLink link:definitionLink link:presentationLink 995573 - Disclosure - Note 5 - Accrued Liabilities (Tables) link:calculationLink link:definitionLink link:presentationLink 995574 - Disclosure - Note 6 - Commitments and Contingencies (Tables) link:calculationLink link:definitionLink link:presentationLink 995575 - Disclosure - Note 9 - Common Stock Warrants and Warrant Liabilities (Tables) link:calculationLink link:definitionLink link:presentationLink 995576 - Disclosure - Note 11 - Stock-based Compensation (Tables) link:calculationLink link:definitionLink link:presentationLink 995577 - Disclosure - Note 13 - Avenova Asset Divestiture and Bridge Loan (Tables) link:calculationLink link:definitionLink link:presentationLink 995578 - Disclosure - Note 14 - Phaseone Divestiture (Tables) link:calculationLink link:definitionLink link:presentationLink 995579 - Disclosure - Note 15 - Dermadoctor Divestiture (Tables) link:calculationLink link:definitionLink link:presentationLink 995580 - Disclosure - Note 16 - Summary of Discontinued Operations (Tables) link:calculationLink link:definitionLink link:presentationLink 995581 - Disclosure - Note 17 - Income Taxes (Tables) link:calculationLink link:definitionLink link:presentationLink 995582 - Disclosure - Note 1 - Organization (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995583 - Disclosure - Note 2 - Summary of Significant Accounting Policies (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995584 - Disclosure - Note 2 - Summary of Significant Accounting Policies - Schedule of Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents (Details) link:calculationLink link:definitionLink link:presentationLink 995585 - Disclosure - Note 2 - Summary of Significant Accounting Policies - Schedule of Earnings Per Share, Basic and Diluted (Details) link:calculationLink link:definitionLink link:presentationLink 995586 - Disclosure - Note 2 - Summary of Significant Accounting Policies - Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share (Details) link:calculationLink link:definitionLink link:presentationLink 995587 - Disclosure - Note 3 - Fair Value Measurements - Assets and Liabilities Measured at Fair Value on a Recurring Basis (Details) link:calculationLink link:definitionLink link:presentationLink 995588 - Disclosure - Note 3 - Fair Value Measurements - Fair Value Valuation Assumptions (Details) link:calculationLink link:definitionLink link:presentationLink 995589 - Disclosure - Note 4 - Prepaid Expenses and Other Current Assets - Summary of Prepaid Expenses and Other Current Assets (Details) link:calculationLink link:definitionLink link:presentationLink 995590 - Disclosure - Note 5 - Accrued Liabilities - Summary of Accrued Liabilities (Details) link:calculationLink link:definitionLink link:presentationLink 995591 - Disclosure - Note 6 - Commitments and Contingencies (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995592 - Disclosure - Note 6 - Commitments and Contingencies - Lease Expense (Details) link:calculationLink link:definitionLink link:presentationLink 995593 - Disclosure - Note 6 - Commitments and Contingencies - Schedule of Future Lease Payments (Details) link:calculationLink link:definitionLink link:presentationLink 995594 - Disclosure - Note 7 - Financing Activities (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995595 - Disclosure - Note 8 - Convertible Notes (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995596 - Disclosure - Note 9 - Common Stock Warrants and Warrant Liabilities (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995597 - Disclosure - Note 9 - Common Stock Warrants and Warrant Liabilities - Schedule of Stockholders' Equity Note, Warrants or Rights (Details) link:calculationLink link:definitionLink link:presentationLink 995598 - Disclosure - Note 9 - Common Stock Warrants and Warrant Liabilities (Details) link:calculationLink link:definitionLink link:presentationLink 995599 - Disclosure - Note 10 - Stockholders' Deficit (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995600 - Disclosure - Note 11 - Stock-based Compensation (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995601 - Disclosure - Note 11 - Stock-based Compensation - Stock Options Outstanding (Details) link:calculationLink link:definitionLink link:presentationLink 995602 - Disclosure - Note 12 - Employee Benefit Plan (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995603 - Disclosure - Note 13 - Avenova Asset Divestiture and Bridge Loan (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995604 - Disclosure - Note 13 - Avenova Asset Divestiture and Bridge Loan - Discontinued Operations (Details) link:calculationLink link:definitionLink link:presentationLink 995605 - Disclosure - Note 14 - Phaseone Divestiture (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995606 - Disclosure - Note 14 - Phaseone Divestiture - Held-for-sale (Details) link:calculationLink link:definitionLink link:presentationLink 995607 - Disclosure - Note 15 - Dermadoctor Divestiture (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995608 - Disclosure - Note 15 - Dermadoctor Divestiture - Discontinued Operations (Details) link:calculationLink link:definitionLink link:presentationLink 995609 - Disclosure - Note 16 - Summary of Discontinued Operations - Disposal Groups, Including Discontinued Operations (Details) link:calculationLink link:definitionLink link:presentationLink 995610 - Disclosure - Note 17 - Income Taxes (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995611 - Disclosure - Note 17 - Income Taxes - Loss Before Provision for Income Taxes (Details) link:calculationLink link:definitionLink link:presentationLink 995612 - Disclosure - Note 17 - Income Taxes - Federal and State Income Tax Provisions (Details) link:calculationLink link:definitionLink link:presentationLink 995613 - Disclosure - Note 17 - Income Taxes - Summary of Deferred Tax Assets and Liabilities (Details) link:calculationLink link:definitionLink link:presentationLink 995614 - Disclosure - Note 17 - Income Taxes - Summary of Net operating Loss and Tax Credit Carryforwards (Details) link:calculationLink link:definitionLink link:presentationLink 995615 - Disclosure - Note 17 - Income Taxes - Unrecognized Tax Benefit (Details) link:calculationLink link:definitionLink link:presentationLink 995616 - Disclosure - Note 17 - Income Taxes - Schedule of Effective Income Tax Rate Reconciliation (Details) link:calculationLink link:definitionLink link:presentationLink 995617 - Disclosure - Note 17 - Income Taxes - Schedule of Income Tax Paid, Net of Refunds (Details) link:calculationLink link:definitionLink link:presentationLink 995618 - Disclosure - Note 18 - Related Party Transactions (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995619 - Disclosure - Note 19 - Subsequent Events (Details Textual) link:calculationLink link:definitionLink link:presentationLink