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        <link:definition>995305 - Disclosure - General</link:definition>   
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        <link:usedOn>link:definitionLink</link:usedOn>     
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        <link:definition>995307 - Disclosure - Material Accounting Policies</link:definition>    
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        <link:usedOn>link:definitionLink</link:usedOn>     
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        <link:definition>995308 - Disclosure - Intangible Assets</link:definition>   
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        <link:usedOn>link:definitionLink</link:usedOn>     
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        <link:definition>995309 - Disclosure - Cash and Cash Equivalents</link:definition> 
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        <link:definition>995311 - Disclosure - Other Current Assets</link:definition> 
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        <link:usedOn>link:definitionLink</link:usedOn>     
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        <link:definition>995312 - Disclosure - Other Payables</link:definition>     
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        <link:usedOn>link:definitionLink</link:usedOn>     
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        <link:usedOn>link:definitionLink</link:usedOn>     
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        <link:definition>995314 - Disclosure - Share-Based Payment Arrangements</link:definition>   
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
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        <link:definition>995315 - Disclosure - Transactions and Balances with Related Parties</link:definition>  
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        <link:usedOn>link:definitionLink</link:usedOn>     
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        <link:definition>995316 - Disclosure - Commitments and Contingent Liabilities</link:definition>    
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        <link:usedOn>link:definitionLink</link:usedOn>     
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        <link:definition>995317 - Disclosure - Research and Development Expenses</link:definition>    
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        <link:usedOn>link:definitionLink</link:usedOn>     
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        <link:definition>995318 - Disclosure - Sales, General and Administrative Expenses</link:definition>   
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        <link:usedOn>link:definitionLink</link:usedOn>     
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        <link:definition>995319 - Disclosure - Finance Expense (Income), Net</link:definition>     
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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        <link:definition>995320 - Disclosure - Taxes on Income</link:definition> 
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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        <link:definition>995321 - Disclosure - Employee Benefits</link:definition>   
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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        <link:definition>995322 - Disclosure - Financial Instruments</link:definition>  
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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        <link:definition>995323 - Disclosure - Subsequent Events</link:definition>   
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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      <link:roleType roleURI="http://Purplebiotech.com/role/AccountingPoliciesByPolicy" id="ppbt_r_AccountingPoliciesByPolicy">   
        <link:definition>996000 - Disclosure - Accounting Policies, by Policy (Policies)</link:definition>  
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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      <link:roleType roleURI="http://Purplebiotech.com/role/BasisofPreparationoftheConsolidatedFinancialStatementsTables" id="ppbt_r_BasisofPreparationoftheConsolidatedFinancialStatementsTables"> 
        <link:definition>996001 - Disclosure - Basis of Preparation of the Consolidated Financial Statements (Tables)</link:definition> 
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
      </link:roleType>   
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        <link:definition>996002 - Disclosure - Intangible Assets (Tables)</link:definition>  
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
      </link:roleType>   
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        <link:definition>996003 - Disclosure - Cash and Cash Equivalents (Tables)</link:definition>     
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        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
      </link:roleType>   
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        <link:definition>996004 - Disclosure - Leases (Tables)</link:definition> 
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
      </link:roleType>   
      <link:roleType roleURI="http://Purplebiotech.com/role/OtherCurrentAssetsTables" id="ppbt_r_OtherCurrentAssetsTables">    
        <link:definition>996005 - Disclosure - Other Current Assets (Tables)</link:definition>     
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
      </link:roleType>   
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        <link:definition>996006 - Disclosure - Other Payables (Tables)</link:definition>    
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
      </link:roleType>   
      <link:roleType roleURI="http://Purplebiotech.com/role/EquityTables" id="ppbt_r_EquityTables">     
        <link:definition>996007 - Disclosure - Equity (Tables)</link:definition> 
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
      </link:roleType>   
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        <link:definition>996008 - Disclosure - Share-Based Payment Arrangements (Tables)</link:definition>  
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
      </link:roleType>   
      <link:roleType roleURI="http://Purplebiotech.com/role/TransactionsandBalanceswithRelatedPartiesTables" id="ppbt_r_TransactionsandBalanceswithRelatedPartiesTables">     
        <link:definition>996009 - Disclosure - Transactions and Balances with Related Parties (Tables)</link:definition> 
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
      </link:roleType>   
      <link:roleType roleURI="http://Purplebiotech.com/role/ResearchandDevelopmentExpensesTables" id="ppbt_r_ResearchandDevelopmentExpensesTables">   
        <link:definition>996010 - Disclosure - Research and Development Expenses (Tables)</link:definition>   
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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      <link:roleType roleURI="http://Purplebiotech.com/role/SalesGeneralandAdministrativeExpensesTables" id="ppbt_r_SalesGeneralandAdministrativeExpensesTables">  
        <link:definition>996011 - Disclosure - Sales, General and Administrative Expenses (Tables)</link:definition>  
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
      </link:roleType>   
      <link:roleType roleURI="http://Purplebiotech.com/role/FinanceExpenseIncomeNetTables" id="ppbt_r_FinanceExpenseIncomeNetTables">    
        <link:definition>996012 - Disclosure - Finance Expense (Income), Net (Tables)</link:definition>    
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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        <link:definition>996013 - Disclosure - Employee Benefits (Tables)</link:definition>  
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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      <link:roleType roleURI="http://Purplebiotech.com/role/FinancialInstrumentsTables" id="ppbt_r_FinancialInstrumentsTables">   
        <link:definition>996014 - Disclosure - Financial Instruments (Tables)</link:definition> 
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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        <link:definition>996015 - Disclosure - General (Details)</link:definition>   
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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      <link:roleType roleURI="http://Purplebiotech.com/role/BasisofPreparationoftheConsolidatedFinancialStatementsDetails" id="ppbt_r_BasisofPreparationoftheConsolidatedFinancialStatementsDetails">   
        <link:definition>996016 - Disclosure - Basis of Preparation of the Consolidated Financial Statements (Details)</link:definition>  
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
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        <link:definition>996017 - Disclosure - Basis of Preparation of the Consolidated Financial Statements - Schedule of Data on Exchange Rates (Details)</link:definition>    
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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      <link:roleType roleURI="http://Purplebiotech.com/role/IntangibleAssetsDetails" id="ppbt_r_IntangibleAssetsDetails">  
        <link:definition>996018 - Disclosure - Intangible Assets (Details)</link:definition>   
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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      <link:roleType roleURI="http://Purplebiotech.com/role/ScheduleofIntangibleAssetsTable" id="ppbt_r_ScheduleofIntangibleAssetsTable">   
        <link:definition>996019 - Disclosure - Intangible Assets - Schedule of Intangible Assets (Details)</link:definition>     
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
      </link:roleType>   
      <link:roleType roleURI="http://Purplebiotech.com/role/ScheduleofCashandCashEquivalentsTable" id="ppbt_r_ScheduleofCashandCashEquivalentsTable">     
        <link:definition>996020 - Disclosure - Cash and Cash Equivalents - Schedule of Cash and Cash Equivalents (Details)</link:definition> 
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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      <link:roleType roleURI="http://Purplebiotech.com/role/LeasesDetails" id="ppbt_r_LeasesDetails">  
        <link:definition>996021 - Disclosure - Leases (Details)</link:definition>  
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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      <link:roleType roleURI="http://Purplebiotech.com/role/ScheduleofCarryingAmountsofRighttoUseAssetsTable" id="ppbt_r_ScheduleofCarryingAmountsofRighttoUseAssetsTable">  
        <link:definition>996022 - Disclosure - Leases - Schedule of Carrying Amounts of Right-to-Use Assets (Details)</link:definition> 
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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      <link:roleType roleURI="http://Purplebiotech.com/role/ScheduleofMaturityAnalysisoftheCompanysLeaseLiabilitiesTable" id="ppbt_r_ScheduleofMaturityAnalysisoftheCompanysLeaseLiabilitiesTable"> 
        <link:definition>996023 - Disclosure - Leases - Schedule of Maturity Analysis of the Company's Lease Liabilities (Details)</link:definition>    
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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      <link:roleType roleURI="http://Purplebiotech.com/role/ScheduleofAmountsRecognizedinProfitorLossTable" id="ppbt_r_ScheduleofAmountsRecognizedinProfitorLossTable">   
        <link:definition>996024 - Disclosure - Leases - Schedule of Amounts Recognized in Profit or Loss (Details)</link:definition>   
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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        <link:definition>996025 - Disclosure - Other Current Assets - Schedule of Other Current Assets (Details)</link:definition> 
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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      <link:roleType roleURI="http://Purplebiotech.com/role/ScheduleofOtherPayablesTable" id="ppbt_r_ScheduleofOtherPayablesTable">  
        <link:definition>996026 - Disclosure - Other Payables - Schedule of Other Payables (Details)</link:definition>    
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
        <link:usedOn>link:calculationLink</link:usedOn> 
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      <link:roleType roleURI="http://Purplebiotech.com/role/EquityDetails" id="ppbt_r_EquityDetails">  
        <link:definition>996027 - Disclosure - Equity (Details)</link:definition>  
        <link:usedOn>link:presentationLink</link:usedOn>  
        <link:usedOn>link:definitionLink</link:usedOn>     
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  <xs:element name="DisclosureOfDetailedInformationAboutEmployeeBenefitsExplanatoryTableTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_DisclosureOfDetailedInformationAboutEmployeeBenefitsExplanatoryTableTextBlock"/>     
  <xs:element name="DisclosureOfDetailedInformationAboutDefinedContributionPlanExplanatoryTableTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_DisclosureOfDetailedInformationAboutDefinedContributionPlanExplanatoryTableTextBlock"/>    
  <xs:element name="ScheduleOfDetailsRegardingFairValueMeasurementTableTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ScheduleOfDetailsRegardingFairValueMeasurementTableTextBlock"/> 
  <xs:element name="FinancialInstrumentsTablesTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_FinancialInstrumentsTablesTable"/> 
  <xs:element name="PercentageOfExchangeRate" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PercentageOfExchangeRate"/>  
  <xs:element name="IntangibleAssetsScheduleofIntangibleAssetsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_IntangibleAssetsScheduleofIntangibleAssetsDetailsTable"/>  
  <xs:element name="CashandCashEquivalentsScheduleofCashandCashEquivalentsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_CashandCashEquivalentsScheduleofCashandCashEquivalentsDetailsTable"/> 
  <xs:element name="LeasesScheduleofCarryingAmountsofRighttoUseAssetsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_LeasesScheduleofCarryingAmountsofRighttoUseAssetsDetailsTable"/> 
  <xs:element name="LeasesScheduleofMaturityAnalysisoftheCompanysLeaseLiabilitiesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_LeasesScheduleofMaturityAnalysisoftheCompanysLeaseLiabilitiesDetailsTable"/>     
  <xs:element name="GovernmentAuthorities" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_GovernmentAuthorities"/>     
  <xs:element name="SalaryRelatedOtherPayablesCurrent" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_SalaryRelatedOtherPayablesCurrent"/>     
  <xs:element name="ClassesOfPreferredSharesDomainDomain" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ClassesOfPreferredSharesDomainDomain"/>    
  <xs:element name="EquityScheduleofShareCapitalDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_EquityScheduleofShareCapitalDetailsTable"/>    
  <xs:element name="EquityScheduleofChangesinShareCapitalDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_EquityScheduleofChangesinShareCapitalDetailsTable"/>  
  <xs:element name="NumberOfIssuanceShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_NumberOfIssuanceShares"/>    
  <xs:element name="NumberOfVestingOfRsus" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_NumberOfVestingOfRsus"/>  
  <xs:element name="NumberOfExerciseOfWarrants" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_NumberOfExerciseOfWarrants"/>  
  <xs:element name="CurrentAsset" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_CurrentAsset"/>  
  <xs:element name="CurrentLiabilitie" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_CurrentLiabilitie"/>  
  <xs:element name="NetAssetsAttributableToNonControllingInterest" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_NetAssetsAttributableToNonControllingInterest"/>   
  <xs:element name="NetAssetsAttributableToNoncontrollingInterests" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_NetAssetsAttributableToNoncontrollingInterests"/> 
  <xs:element name="ShareBasedPaymentArrangementsScheduleofAssumptionswereUsedDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_ShareBasedPaymentArrangementsScheduleofAssumptionswereUsedDetailsTable"/>    
  <xs:element name="ShareBasedPaymentArrangementsScheduleofExpensesRecognizedintheConsolidatedFinancialStatementsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_ShareBasedPaymentArrangementsScheduleofExpensesRecognizedintheConsolidatedFinancialStatementsDetailsTable"/>    
  <xs:element name="TransactionsandBalanceswithRelatedPartiesScheduleofRecordedExpensesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_TransactionsandBalanceswithRelatedPartiesScheduleofRecordedExpensesDetailsTable"/>  
  <xs:element name="ResearchandDevelopmentExpensesScheduleofResearchandDevelopmentExpensesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_ResearchandDevelopmentExpensesScheduleofResearchandDevelopmentExpensesDetailsTable"/>   
  <xs:element name="SalesGeneralandAdministrativeExpensesScheduleofSalesGeneralandAdministrativeExpensesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_SalesGeneralandAdministrativeExpensesScheduleofSalesGeneralandAdministrativeExpensesDetailsTable"/> 
  <xs:element name="ReimbursementOfLegalFeesExpense" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ReimbursementOfLegalFeesExpense"/>  
  <xs:element name="GeneralAndAdministrativeExpensesOther" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_GeneralAndAdministrativeExpensesOther"/>   
  <xs:element name="IssuanceExpenses" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_IssuanceExpenses"/> 
  <xs:element name="OtherfinancialCost" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_OtherfinancialCost"/>     
  <xs:element name="OtherExpense" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_OtherExpense"/>   
  <xs:element name="FinancialInstrumentsScheduleofSensitivityTesttoPossibleChangesinExchangeRateDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_FinancialInstrumentsScheduleofSensitivityTesttoPossibleChangesinExchangeRateDetailsTable"/>     
  <xs:element name="IncomelossFromChangeInExchangeRateDown" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_IncomelossFromChangeInExchangeRateDown"/> 
  <xs:element name="IncomelossValue" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_IncomelossValue"/>     
  <xs:element name="IncomelossFromChangeInExchangeRateUp" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_IncomelossFromChangeInExchangeRateUp"/>  
  <xs:element name="FinancialInstrumentsScheduleofFinancialInstrumentsMeasuredatFairValueDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_FinancialInstrumentsScheduleofFinancialInstrumentsMeasuredatFairValueDetailsTable"/> 
  <xs:element name="FinancialInstrumentsScheduleofDetailsRegardingFairValueMeasurementDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_FinancialInstrumentsScheduleofDetailsRegardingFairValueMeasurementDetailsTable"/>     
  <xs:element name="FairValueMeasurementBalance" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_FairValueMeasurementBalance"/>   
  <xs:element name="FairValueMeasurementExercise" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_FairValueMeasurementExercise"/> 
  <xs:element name="FairValueMeasurementIssuance" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_FairValueMeasurementIssuance"/> 
  <xs:element name="FairValueMeasurementRevaluation" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_FairValueMeasurementRevaluation"/> 
  <xs:element name="FairValueMeasurementIssuanceProceed" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_FairValueMeasurementIssuanceProceed"/>     
  <xs:element name="FinancialInstrumentsScheduleofFairValueMeasurementDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_FinancialInstrumentsScheduleofFairValueMeasurementDetailsTable"/>   
  <xs:element name="DescriptionOfOptionLifeShareOptionGranted" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_DescriptionOfOptionLifeShareOptionGranted"/>    
  <xs:element name="ExpectedDividendAsPercentageShareOptionsdividendYield" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ExpectedDividendAsPercentageShareOptionsdividendYield"/>     
  <xs:element name="GeneralDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_GeneralDetailsTable"/>  
  <xs:element name="AmericanDepositorySharesOrdinaryShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_AmericanDepositorySharesOrdinaryShares"/> 
  <xs:element name="CommonStockNoParValues" type="dtr:perShareItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="ppbt_CommonStockNoParValues"/>   
  <xs:element name="StockholdersEquityReversesStockSplit" type="xbrli:stringItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_StockholdersEquityReversesStockSplit"/>  
  <xs:element name="PercentageOfContractToAcquire" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PercentageOfContractToAcquire"/>  
  <xs:element name="RetainedEarning" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_RetainedEarning"/>     
  <xs:element name="PrivateAndPublicFinancingTotal" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PrivateAndPublicFinancingTotal"/>    
  <xs:element name="FunctionalCurrency" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_FunctionalCurrency"/> 
  <xs:element name="IntangibleAssetsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_IntangibleAssetsDetailsTable"/>     
  <xs:element name="EquityMethodInvestmentsOwnershipPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_EquityMethodInvestmentsOwnershipPercentage"/>   
  <xs:element name="TotalAcquisitionAmount" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_TotalAcquisitionAmount"/>    
  <xs:element name="AggregateUpfrontPayment" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_AggregateUpfrontPayment"/> 
  <xs:element name="LongTermMilestonesAggregateAmount" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_LongTermMilestonesAggregateAmount"/> 
  <xs:element name="IntangibleAssetsRecoverableAmountPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_IntangibleAssetsRecoverableAmountPercentage"/>     
  <xs:element name="AggregateShareholdersOfImmunorizon" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_AggregateShareholdersOfImmunorizon"/>   
  <xs:element name="LeasesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_LeasesDetailsTable"/>     
  <xs:element name="AgreementLeaseTerm" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_AgreementLeaseTerm"/>   
  <xs:element name="AgreementLeaseAdditionalTerm" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_AgreementLeaseAdditionalTerm"/>   
  <xs:element name="EquityDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_EquityDetailsTable"/>     
  <xs:element name="NonVotingSeniorPreferredShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_NonVotingSeniorPreferredShares"/>     
  <xs:element name="ReverseRatio" type="xbrli:stringItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ReverseRatio"/>    
  <xs:element name="NumberOfNonTradableWarrants" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_NumberOfNonTradableWarrants"/>    
  <xs:element name="WarrantsIssued" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_WarrantsIssued"/>   
  <xs:element name="WarrantsExercised" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_WarrantsExercised"/>    
  <xs:element name="OfferingPricePerShare" type="dtr1:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_OfferingPricePerShare"/>   
  <xs:element name="PreFundedWarant" type="dtr1:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PreFundedWarant"/> 
  <xs:element name="AggregateGrossProceeds" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_AggregateGrossProceeds"/>    
  <xs:element name="NetPlacementAgentFees" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_NetPlacementAgentFees"/>  
  <xs:element name="WarrantExercisableExpirePeriod" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_WarrantExercisableExpirePeriod"/>  
  <xs:element name="PreFundExercisePriceWarrants" type="dtr1:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PreFundExercisePriceWarrants"/>  
  <xs:element name="FundsRaisedAmount" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_FundsRaisedAmount"/>  
  <xs:element name="FundsRaisedshares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_FundsRaisedshares"/>    
  <xs:element name="WarrantsExercisableTerm" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_WarrantsExercisableTerm"/>   
  <xs:element name="DepositaryShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_DepositaryShares"/>  
  <xs:element name="PurchaseOfCommonStockAndWarrants" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PurchaseOfCommonStockAndWarrants"/>    
  <xs:element name="WarrantsTerm" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_WarrantsTerm"/> 
  <xs:element name="IssuesOfEquity" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_IssuesOfEquity"/>   
  <xs:element name="ExerciseOfWarrantsEquity" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ExerciseOfWarrantsEquity"/>  
  <xs:element name="WarrantTermDescription" type="xbrli:stringItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_WarrantTermDescription"/>    
  <xs:element name="SalesAgreementShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_SalesAgreementShares"/>     
  <xs:element name="noncontrollingInterests" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_noncontrollingInterests"/>     
  <xs:element name="ShareBasedPaymentArrangementsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_ShareBasedPaymentArrangementsDetailsTable"/> 
  <xs:element name="OptionExerciseOrdinaryShare" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_OptionExerciseOrdinaryShare"/>    
  <xs:element name="VestingPeriod" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_VestingPeriod"/>   
  <xs:element name="ExercisePeriod" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ExercisePeriod"/>     
  <xs:element name="ConsultantPerShares" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ConsultantPerShares"/>   
  <xs:element name="AmericanDepostioryShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_AmericanDepostioryShares"/>   
  <xs:element name="ConvertibleShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ConvertibleShares"/>    
  <xs:element name="PercentageOfCapacityOfAnAdvisor" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PercentageOfCapacityOfAnAdvisor"/> 
  <xs:element name="RangesDomainDomain" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_RangesDomainDomain"/>   
  <xs:element name="CommitmentsandContingentLiabilitiesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_CommitmentsandContingentLiabilitiesDetailsTable"/>   
  <xs:element name="PercentageOfSublicenseConsideration" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PercentageOfSublicenseConsideration"/>    
  <xs:element name="PercentageOfReceiveExitFee" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PercentageOfReceiveExitFee"/> 
  <xs:element name="GainLossOnWarrants" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_GainLossOnWarrants"/> 
  <xs:element name="StatutoryTaxRate" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_StatutoryTaxRate"/> 
  <xs:element name="EffectiveTaxRate" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_EffectiveTaxRate"/> 
  <xs:element name="UnrecognizedResearchAndDevelopmentExpenses" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_UnrecognizedResearchAndDevelopmentExpenses"/>   
  <xs:element name="EmployeeBenefitBonus" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_EmployeeBenefitBonus"/>    
  <xs:element name="EmployeeBenefitsLiabilityDueGrants" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_EmployeeBenefitsLiabilityDueGrants"/>  
  <xs:element name="FinancialInstrumentsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_FinancialInstrumentsDetailsTable"/>   
  <xs:element name="ShortTermDepositsGuaranteedForLeasesAndCredit" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ShortTermDepositsGuaranteedForLeasesAndCredit"/>    
  <xs:element name="ShortTermDepositsGuaranteedForHedgingTransactions" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ShortTermDepositsGuaranteedForHedgingTransactions"/>  
  <xs:element name="ConvertibleWarrants" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ConvertibleWarrants"/>   
  <xs:element name="TerminationExercisePrice" type="dtr:perShareItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="ppbt_TerminationExercisePrice"/>  
  <xs:element name="WarrantExercisePricePerShare" type="dtr:perShareItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="ppbt_WarrantExercisePricePerShare"/>     
  <xs:element name="DepositarysShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_DepositarysShares"/>    
  <xs:element name="AggregateWarrantsShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_AggregateWarrantsShares"/> 
  <xs:element name="SubsequentEventsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_SubsequentEventsDetailsTable"/>     
  <xs:element name="ClassesOfPreferredSharesAxis" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:dimensionItem" id="ppbt_ClassesOfPreferredSharesAxis"/>     
  <xs:element name="RangesAxis" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:dimensionItem" id="ppbt_RangesAxis"/>    
  <xs:element name="ADSMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ADSMember"/>     
  <xs:element name="ATMProgramMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ATMProgramMember"/>    
  <xs:element name="AccountPayablesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_AccountPayablesMember"/>    
  <xs:element name="AdsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_AdsMember"/>     
  <xs:element name="BiopharmaceuticalProductMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_BiopharmaceuticalProductMember"/>  
  <xs:element name="BoardOfDirectorsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_BoardOfDirectorsMember"/> 
  <xs:element name="CapitalReserveFromTransactionsWithNonControllingInterestMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_CapitalReserveFromTransactionsWithNonControllingInterestMember"/> 
  <xs:element name="CapitalReserveFromTransactionsWithRelatedPartiesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_CapitalReserveFromTransactionsWithRelatedPartiesMember"/>     
  <xs:element name="CashAndCashEquivalentsAndDepositsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_CashAndCashEquivalentsAndDepositsMember"/>     
  <xs:element name="ClassEPreferredSharesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ClassEPreferredSharesMember"/> 
  <xs:element name="DiagnosticProductsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_DiagnosticProductsMember"/>     
  <xs:element name="DownRangeOneMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_DownRangeOneMember"/>   
  <xs:element name="EUROMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_EUROMember"/>  
  <xs:element name="FinancialAssetConvertibleNoteMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_FinancialAssetConvertibleNoteMember"/>  
  <xs:element name="FinancialLiabilityWarrantMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_FinancialLiabilityWarrantMember"/>    
  <xs:element name="IPRDRelatedToFamewaveSee5BBelowMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_IPRDRelatedToFamewaveSee5BBelowMember"/> 
  <xs:element name="IPRDRelatedToImmunorizonSee5CBelowMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_IPRDRelatedToImmunorizonSee5CBelowMember"/>  
  <xs:element name="IPRDRelatedToPurpleGmbHMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_IPRDRelatedToPurpleGmbHMember"/>     
  <xs:element name="IPRDRelatedToTryNovosee5ABelowMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_IPRDRelatedToTryNovosee5ABelowMember"/>    
  <xs:element name="LeaseAgreementOneMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_LeaseAgreementOneMember"/>   
  <xs:element name="LeaseAgreementsTwoMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_LeaseAgreementsTwoMember"/>     
  <xs:element name="NISMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_NISMember"/>     
  <xs:element name="OrdinaryShareMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_OrdinaryShareMember"/>     
  <xs:element name="OtherCurrentAssetMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_OtherCurrentAssetMember"/>   
  <xs:element name="OtherPayablesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_OtherPayablesMember"/>     
  <xs:element name="PostemploymentBenefitLiabilitiesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PostemploymentBenefitLiabilitiesMember"/>   
  <xs:element name="PreferredClassCMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PreferredClassCMember"/>    
  <xs:element name="PreferredClassDMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PreferredClassDMember"/>    
  <xs:element name="PreferredShareClassBMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PreferredShareClassBMember"/>    
  <xs:element name="PreferredShareClassMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PreferredShareClassMember"/>  
  <xs:element name="PrivatePlacementsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PrivatePlacementsMember"/>   
  <xs:element name="PublicOfferingMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_PublicOfferingMember"/>  
  <xs:element name="ReceiptsOnAccountOfWarrantsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ReceiptsOnAccountOfWarrantsMember"/>   
  <xs:element name="RehovotMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_RehovotMember"/>   
  <xs:element name="ResearchAndDevelopmentExpensesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ResearchAndDevelopmentExpensesMember"/>    
  <xs:element name="SalariesWagesAndRelatedExpensesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_SalariesWagesAndRelatedExpensesMember"/> 
  <xs:element name="September2025OfferingMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_September2025OfferingMember"/> 
  <xs:element name="SeriesA1WarrantsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_SeriesA1WarrantsMember"/> 
  <xs:element name="SeriesA2WarrantsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_SeriesA2WarrantsMember"/> 
  <xs:element name="ServiceProvidersMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ServiceProvidersMember"/> 
  <xs:element name="ShareBasedPaymentArrangementsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ShareBasedPaymentArrangementsMember"/>  
  <xs:element name="ShareBasedPaymentsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ShareBasedPaymentsMember"/>     
  <xs:element name="SubsequentEventsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_SubsequentEventsMember"/> 
  <xs:element name="THMMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_THMMember"/>     
  <xs:element name="TryNovosTechnologiesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_TryNovosTechnologiesMember"/>    
  <xs:element name="UpRangeOneMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_UpRangeOneMember"/>    
  <xs:element name="WarrantsoneMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_WarrantsoneMember"/> 
  <xs:element name="YissumsLicensedTechnologyMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_YissumsLicensedTechnologyMember"/>    
  <xs:element name="CommitmentsAndContingentLiabilitiesAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_CommitmentsAndContingentLiabilitiesAbstract"/>     
  <xs:element name="CommitmentsAndContingentLiabilitiesLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_CommitmentsAndContingentLiabilitiesLineItems"/>  
  <xs:element name="FinanceExpenseIncomeNetAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_FinanceExpenseIncomeNetAbstract"/> 
  <xs:element name="FinancialInstrumentsLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_FinancialInstrumentsLineItems"/>  
  <xs:element name="GeneralLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_GeneralLineItems"/> 
  <xs:element name="IntangibleAssetsLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_IntangibleAssetsLineItems"/>    
  <xs:element name="ItemsThatWillBeTransferredToProfitOrLossAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ItemsThatWillBeTransferredToProfitOrLossAbstract"/>     
  <xs:element name="LeasesLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_LeasesLineItems"/>    
  <xs:element name="LossPerADSInformationwhere1ADSRepresents2000SharesAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_LossPerADSInformationwhere1ADSRepresents2000SharesAbstract"/>     
  <xs:element name="ResearchAndDevelopmentExpensesAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ResearchAndDevelopmentExpensesAbstract"/>     
  <xs:element name="ScheduleOfCashAndCashEquivalentsLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ScheduleOfCashAndCashEquivalentsLineItems"/> 
  <xs:element name="ScheduleOfDefinedContributionPlanInRespectOfItsEmployeesAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ScheduleOfDefinedContributionPlanInRespectOfItsEmployeesAbstract"/>  
  <xs:element name="ScheduleOfFinanceExpensesAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ScheduleOfFinanceExpensesAbstract"/>     
  <xs:element name="ScheduleOfFinanceIncomeAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ScheduleOfFinanceIncomeAbstract"/> 
  <xs:element name="ScheduleOfPostEmployeeBenefitsAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ScheduleOfPostEmployeeBenefitsAbstract"/>     
  <xs:element name="ScheduleOfResearchAndDevelopmentExpensesLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ScheduleOfResearchAndDevelopmentExpensesLineItems"/>  
  <xs:element name="ScheduleOfSalesGeneralAndAdministrativeExpensesLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_ScheduleOfSalesGeneralAndAdministrativeExpensesLineItems"/> 
  <xs:element name="StatementsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ppbt_StatementsTable"/>    
  <xs:element name="TaxesOnIncomeabstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_TaxesOnIncomeabstract"/> 
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  <xs:element name="DocumentAndEntityInformationAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ppbt_DocumentAndEntityInformationAbstract"/> 
</xs:schema>
