v3.26.1
Commitments and contingencies - Operating Leases and Finance Leases (Details) - USD ($)
$ in Thousands
 1 Months Ended 12 Months Ended
Dec. 06, 2021
Jan. 31, 2023
Dec. 31, 2025
Dec. 31, 2023
Dec. 31, 2024
Dec. 31, 2021
Leases            
Non-cash impact to operating lease right-of-use assets and operating lease liabilities     $ 12,383 $ 3,898    
Finance lease right-of-use assets     $ 800   $ 1,000  
Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]     Property, Plant and Equipment, Net   Property, Plant and Equipment, Net  
Finance lease liabilities     $ 874   $ 1,000  
Finance Lease, Liability, Statement of Financial Position [Extensible Enumeration]     Accrued Liabilities, Current, Other Liabilities, Noncurrent   Accrued Liabilities, Current, Other Liabilities, Noncurrent  
Office and laboratory space in Cambridge Massachusetts            
Leases            
Lease total contractual Term   3 years        
Leases, term of contract   3 years        
New Office and laboratory space in Cambridge, United Kingdom            
Leases            
Lease total contractual Term 10 years          
Leases, term of contract 5 years   5 years      
Rent-free period     9 months      
Renewal term     10 years      
Non-cash impact to operating lease right-of-use assets and operating lease liabilities     $ 12,400      
Office and laboratory space in Building 900, Babraham Research Campus, Cambridge            
Leases            
Renewal term           5 years
Loss on lease termination       $ (300)