Property and equipment, net (Details) - USD ($) $ in Thousands	12 Months Ended
Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Property and equipment, net
Finance lease right-of-use assets	$ 1,106	$ 1,033
Property and equipment, gross	32,199	28,465
Less: Accumulated depreciation and amortization	(26,178)	(18,949)
Property and equipment, net	6,021	9,516
Depreciation and amortization expense	6,400	7,200	$ 6,500
Amortization expense of property and equipment under finance leases	217	53	$ 0
Laboratory equipment
Property and equipment, net
Property and equipment	17,564	14,658
Leasehold improvements
Property and equipment, net
Property and equipment	12,031	10,903
Computer equipment and software
Property and equipment, net
Property and equipment	634	581
Furniture and office equipment
Property and equipment, net
Property and equipment	$ 864	$ 1,290

The current period expense charged against earnings on long-lived, physical assets not used in production, and which are not intended for resale, to allocate or recognize the cost of such assets over their useful lives; or to record the reduction in book value of an intangible asset over the benefit period of such asset; or to reflect consumption during the period of an asset that is not used in production.

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