v3.26.1
Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Consolidated Statements of Operations and Comprehensive Loss      
Collaboration revenue $ 72,586 $ 35,275 $ 26,976
Operating expenses:      
Research and development 240,283 172,966 156,496
General and administrative 79,368 72,181 60,426
Total operating expenses 319,651 245,147 216,922
Loss from operations (247,065) (209,872) (189,946)
Other income (expense):      
Interest and other income 28,463 34,284 14,002
Interest expense (206) (1,730) (3,263)
Loss on extinguishment of debt   (954)  
Gain on extinguishment of research and development funding liability   4,476  
Total other income, net 28,257 36,076 10,739
Net loss before income tax provision (218,808) (173,796) (179,207)
Provision for (benefit from) income taxes 152 (4,765) 1,457
Net loss $ (218,960) $ (169,031) $ (180,664)
Net loss per share, basic (in dollars per share) $ (3.16) $ (2.9) $ (5.08)
Net loss per share, diluted (in dollars per share) $ (3.16) $ (2.9) $ (5.08)
Weighted average ordinary shares outstanding, basic (in shares) 69,279,838 58,207,593 35,592,362
Weighted average ordinary shares outstanding, diluted (in shares) 69,279,838 58,207,593 35,592,362
Comprehensive loss:      
Net loss $ (218,960) $ (169,031) $ (180,664)
Other comprehensive income (loss):      
Foreign currency translation adjustment (3,624) 1,423 (1,691)
Total comprehensive loss $ (222,584) $ (167,608) $ (182,355)