v3.26.1
Commitments and Contingencies, Including License and Sponsored Research Agreements - Additional Information (Details) - USD ($)
 1 Months Ended 12 Months Ended 34 Months Ended
Jan. 01, 2026
Jan. 01, 2025
Mar. 16, 2023
Oct. 06, 2020
Jun. 30, 2025
Aug. 31, 2022
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2025
May 04, 2023
Commitments And Contingencies [Line Items]                    
Accrued expenses             $ 3,612,913 $ 1,388,060 $ 3,612,913  
Minimum                    
Commitments And Contingencies [Line Items]                    
Percentage of royalties owed on sublicense income           10.00%        
Maximum                    
Commitments And Contingencies [Line Items]                    
Percentage of royalties owed on sublicense income           20.00%        
DRL Agreement                    
Commitments And Contingencies [Line Items]                    
Pre-approval regulatory milestone payments     $ 2,900,000              
Aggregate regulatory milestone payments             1,200,000   1,000,000  
Additional payments of other development and sales milestones     20,000,000              
Accrued expenses             200,000   200,000  
License agreement upfront fee     $ 400,000              
ARScience License Agreement                    
Commitments And Contingencies [Line Items]                    
Aggregate regulatory milestone payments             1,100,000      
Accrued expenses             700,000   700,000  
Developmental milestones           $ 5,900,000        
ARScience License Agreement | First Combination Product                    
Commitments And Contingencies [Line Items]                    
Developmental milestones           13,300,000        
ARScience License Agreement | Combination Product                    
Commitments And Contingencies [Line Items]                    
Developmental milestones           11,600,000        
ARScience License Agreement | First Mono Product                    
Commitments And Contingencies [Line Items]                    
Developmental milestones           11,800,000        
ARScience License Agreement | Mono Product                    
Commitments And Contingencies [Line Items]                    
Developmental milestones           $ 5,900,000        
Methodist License                    
Commitments And Contingencies [Line Items]                    
Accrued expenses             $ 100,000   $ 100,000  
License termination condition description.             The Methodist License Agreement provides that in the event the Company sublicense products and services covered by the Methodist License Agreement, then royalties owed to Houston Methodist would be computed as a percentage of payments received by the Company from the sublicensee. In addition, the termination provisions provide that Houston Methodist may terminate the Methodist License Agreement, among other things, in the event that after five years the Company is not “Actively Attempting to Develop or Commercialize,” as such term is defined in the Methodist License Agreement. During the year ended December 31, 2025, the Company incurred $0.1 million in milestone payments to Methodist as in-process research and development expense, in connection with Company's FTD IND Milestone and Dosing Milestone. As of December 31, 2025, $0.1 million was included in accrued expenses in the accompanying balance sheets.      
Milestone payments             $ 100,000      
Maximum aggregate amount payable upon milestone achievement of specific development and regulatory events.       $ 400,000            
Minimum annual amount owned upon commercialization   $ 100,000                
Methodist research fund                   $ 500,000
Sponsored Research Agreement                    
Commitments And Contingencies [Line Items]                    
Minimum Total Funding         $ 1,200,000          
Maximum Total Funding         $ 1,400,000          
Research and development expenses             $ 1,000,000 $ 500,000    
Sponsored Research Agreement | Subsequent Event                    
Commitments And Contingencies [Line Items]                    
Maximum funding $ 600,000