75000 - Document - Document and Entity Information
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75010 - Statement - BALANCE SHEETS
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75020 - Statement - BALANCE SHEETS (Parenthetical)
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75030 - Statement - STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME (LOSS)
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75040 - Statement - STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME (LOSS) 2
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75050 - Statement - STATEMENTS OF STOCKHOLDERS' DEFICIT
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75060 - Statement - STATEMENTS OF CASH FLOWS
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995457 - Disclosure - Cybersecurity Risk Management, Strategy and Governance
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995467 - Disclosure - Description of the Business
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995477 - Disclosure - Basis of Presentation and Summary of Significant Accounting Policies
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995487 - Disclosure - Recent Accounting Pronouncements
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995497 - Disclosure - Net Income (Loss) Per Share
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995507 - Disclosure - Fair Value Measurements and Investments
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995517 - Disclosure - Property and Equipment
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995527 - Disclosure - Intangible Asset
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995537 - Disclosure - Accrued Liabilities
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995547 - Disclosure - Collaboration and License Agreements
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995557 - Disclosure - License Agreement
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995567 - Disclosure - Commitments and Contingencies
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995577 - Disclosure - Leases
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995587 - Disclosure - Common Stock
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995597 - Disclosure - Stock-based Compensation
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995607 - Disclosure - Income Taxes
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995617 - Disclosure - Defined Contribution Plan
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995627 - Disclosure - Segment
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995637 - Disclosure - Restructuring
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995647 - Disclosure - Selected Quarterly Financial Data (Unaudited)
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995657 - Disclosure - Subsequent Event
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995667 - Disclosure - Basis of Presentation and Summary of Significant Accounting Policies (Policies)
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995677 - Disclosure - Basis of Presentation and Summary of Significant Accounting Policies (Tables)
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995687 - Disclosure - Net Income (Loss) Per Share (Tables)
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995697 - Disclosure - Fair Value Measurements and Investments (Tables)
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995707 - Disclosure - Property and Equipment (Tables)
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995717 - Disclosure - Intangible Asset (Tables)
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995727 - Disclosure - Accrued Liabilities (Tables)
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995737 - Disclosure - Collaboration and License Agreements (Tables)
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995747 - Disclosure - Leases (Tables)
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995757 - Disclosure - Common Stock (Tables)
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995767 - Disclosure - Stock-based Compensation (Tables)
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995777 - Disclosure - Income Taxes (Tables)
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995787 - Disclosure - Segment (Tables)
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995797 - Disclosure - Restructuring (Tables)
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995807 - Disclosure - Selected Quarterly Financial Data (Unaudited) (Tables)
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995817 - Disclosure - Basis of Presentation and Summary of Significant Accounting Policies - Additional Information (Details)
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995827 - Disclosure - Basis of Presentation and Summary of Significant Accounting Policies - Schedule of Cash, Cash Equivalents, and Restricted Cash (Details)
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995837 - Disclosure - Basis of Presentation and Summary of Significant Accounting Policies - Schedule of Useful Lives of Property and Equipment (Details)
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995847 - Disclosure - Recent Accounting Pronouncements - Additional Information (Details)
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995857 - Disclosure - Net Income (Loss) Per Share - Summary of Calculation of Basic and Diluted Net Income (Loss) Per Share (Details)
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995867 - Disclosure - Net Income (Loss) Per Share - Summary of Potentially Dilutive Securities Excluded from Computation of Diluted Net Loss Per Share (Details)
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995877 - Disclosure - Fair Value Measurements and Investments - Schedule of Investments Subject to Fair Value Measurements on a Recurring Basis (Details)
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995887 - Disclosure - Property and Equipment - Summary of Property and Equipment, Net (Details)
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995897 - Disclosure - Property and Equipment - Additional Information (Details)
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995907 - Disclosure - Intangible Asset - Additional Information (Details)
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995917 - Disclosure - Intangible Asset - Schedule of Intangible Assets (Details)
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995927 - Disclosure - Accrued Liabilities - Summary of Accrued Liabilities (Details)
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995937 - Disclosure - Collaboration and License Agreements - Schedule of Revenue by Collaboration Partners (Details)
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995947 - Disclosure - Collaboration and License Agreements - Amgen, Inc - Additional Information (Details)
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995957 - Disclosure - Collaboration and License Agreements - Astellas Pharma Inc - Additional Information (Details)
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995967 - Disclosure - Collaboration and License Agreements - Bristol-Myers Squibb Company - Additional Information (Details)
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995977 - Disclosure - Collaboration and License Agreements - ModernaTX, Inc - Additional Information (Details)
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995987 - Disclosure - Collaboration and License Agreements - Regeneron Pharmaceuticals, Inc - Additional Information (Details)
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995997 - Disclosure - Collaboration and License Agreements - Summary of Contract Liabilities (Details)
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996007 - Disclosure - Collaboration and License Agreements - Contract Liabilities - Additional Information (Details)
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996017 - Disclosure - License Agreement - Additional Information (Details)
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996027 - Disclosure - Commitments and Contingencies - Additional Information (Details)
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996037 - Disclosure - Leases - Additional Information (Details)
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996047 - Disclosure - Leases - Summary of Supplemental Information Related to Leases (Details)
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996057 - Disclosure - Leases - Summary of Lease Cost (Details)
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996067 - Disclosure - Leases - Schedule of Maturity of Operating Lease Liabilities (Details)
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996077 - Disclosure - Leases - Schedule of Maturity of Operating Lease Liabilities (Details) 2
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996087 - Disclosure - Leases - Schedule of Two Thousand Twenty Six Lease Maturity of Operating Lease Liabilities (Details)
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996097 - Disclosure - Common Stock - Additional Information (Details)
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996107 - Disclosure - Common Stock - Summary of Company's warrants (Details)
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996117 - Disclosure - Stock-based Compensation - Additional Information (Details)
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996127 - Disclosure - Stock-based Compensation - Schedule of Activities Under Company's Stock Option Plans (Details)
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996137 - Disclosure - Stock-based Compensation - Schedule of Company's TRSU Activities (Details)
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996147 - Disclosure - Stock-based Compensation - Schedule of Activities for Company's PSUs (Details)
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996157 - Disclosure - Stock-based Compensation - Total Stock-based Compensation Recognized (Details)
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996167 - Disclosure - Stock-based Compensation - Schedule of Estimated Fair Value of Employee Stock Options and ESPP Using Black-Scholes Valuation Model (Details)
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996177 - Disclosure - Income Taxes - Additional Information (Details)
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996187 - Disclosure - Income Taxes - Schedule of Components of Provision for Income Taxes (Details)
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996197 - Disclosure - Income Taxes - Schedule of Effective Tax Rate Reconciliation (Details)
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996207 - Disclosure - Income Taxes - Schedule of Effective Tax Rate Reconciliation (Details) 2
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996217 - Disclosure - Income Taxes - Schedule of Deferred Income Tax Assets and Liabilities (Details)
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996227 - Disclosure - Income Taxes - Schedule of Reconciliation of Unrecognized Tax Benefits (Details)
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996237 - Disclosure - Defined Contribution Plan - Additional Information (Details)
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996247 - Disclosure - Segment - Schedule of Revenue and Expenses (Details)
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996257 - Disclosure - Segment - Additional Information (Details)
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996267 - Disclosure - Restructuring - Additional Information (Details)
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996277 - Disclosure - Restructuring - Summary of Accrued Restructuring Costs (Details)
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996287 - Disclosure - Subsequent Event - Additional Information (Details)
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Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Units vested
Accelerated recognition of deferred revenue.
Accelerated Recognition Of Deferred Revenue [Member]
Accelerated Recognition of Deferred Revenue
Restructuring cost, Beginning Balance
Restructuring Reserve, Total
Restructuring Reserve
Restructuring expenses
Balance at December 31, 2025
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Preferred Stock, Shares Issued
Convertible Preferred stock, shares issued
Preferred Stock, Shares Issued, Total
Share-Based Compensation Arrangements by Share-Based Payment Award, Performance-Based Units, Vested and Expected to Vest [Table Text Block]
Schedule of Activities for Company's PSUs
Tranche One Warrant [Member]
Tranche one warrant.
Tranche one Warrant
Increase (Decrease) in Accounts Payable
Accounts payable
Increase (Decrease) in Accounts Payable, Total
Revision of Prior Period [Axis]
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Supplemental disclosures of noncash financing items:
Tax Credit Carryforward Expiration Year
Tax credit carryforward, expiration
Tax credit carryforward expiration year.
Plan Name [Axis]
Plan Name
Equity [Abstract]
Entity Current Reporting Status
Entity Current Reporting Status
Operating Expenses [Abstract]
Operating expenses:
Expired
Class of Warrant or Right Expired
Class of warrant or right expired.
Fair Value, Inputs, Level 2 [Member]
Level II
Deferred Tax Assets, Net of Valuation Allowance
Deferred tax assets, net of valuation allowance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Options Outstanding, Weighted-Average Exercise Price Per Share
Weighted - Average Purchase Price
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Common Stock, Shares Authorized
Common stock, shares authorized
Product and Service [Axis]
Product and Service
Document Fiscal Period Focus
Document Fiscal Period Focus
Revenue from Contract with Customer [Abstract]
Entity Shell Company
Entity Shell Company
Other Accrued Liabilities, Current
Other accrued expenses
Segment Reporting, Policy [Policy Text Block]
Segments
Cash and Cash Equivalent
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Denominator:
Weighted Average Number of Shares Outstanding Reconciliation [Abstract]
Estimated research fund.
Estimated Research Fund
Estimated research fund
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Research and Development Arrangement, Contract to Perform for Others, Type
Cybersecurity Risk Management, Strategy, and Governance [Abstract]
Common Stock, Shares, Issued
Common stock, shares issued
Common Stock, Shares, Issued, Total
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag]
Cybersecurity Risk Board of Directors Oversight [Text Block]
Lessee, Operating Lease, Description
Lease term description
Asset Class [Domain]
Asset Class
Statement [Table]
Statement [Table]
Sublicense fees.
Sublicense Fees
Sublicense fees
Restricted Cash, Noncurrent
Restricted cash - non-current assets
Restricted cash
Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions
Additions based on tax positions related to current year
Upfront consideration, pre-paid research and development service fees
Up Front Consideration Pre Paid Research And Development Service Fees
Up front consideration pre paid research and development service fees.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value, options granted
RSU's Awarded
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Estimated fair value of the shares on the date of grant
Statement [Line Items]
Statement [Line Items]
Revenue from Contract with Customer [Policy Text Block]
Contract Balances
Milestone payment received.
Milestone Payment Received
Milestone payments received
Loss Contingency, Lawsuit Filing Date
Lawsuit filed date
Common stock warrants
Warrant [Member]
Amount of increase decrease in unrecognized tax benefits resulting from tax positions taken in prior period tax returns.
Unrecognized Tax Benefits Increase Decrease Resulting From Prior Period Tax Positions
Adjustment based on tax positions related to prior years
Entity Filer Category
Entity Filer Category
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Liabilities and Equity
Total liabilities and stockholders' equity (deficit)
Total liabilities and stockholders' equity (deficit)
Changes in unrecognized tax benefits
Effective Income Tax Rate Reconciliation, Tax Contingency, Percent
Effective Income Tax Rate Reconciliation, Tax Contingency, Percent, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Options Exercisable, end of the period
Restructuring Type [Axis]
Royalty obligations future minimum payments due.
Royalty Obligations Future Minimum Payments Due
Annual minimum royalty obligations
Long-Lived Tangible Asset [Axis]
Long-Lived Tangible Asset
Period of nomination of additional target.
Period Of Nomination Of Additional Target
Period of nomination of additional target from effective date
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Deferred tax asset, net change in total valuation allowance increase/decrease during period
Regents of the university of California.
Regents Of The University Of California [Member]
UC Regents
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag]
Stock based compensation
Stock Based Compensation [Member]
Stock Based Compensation
Restructuring and Related Costs [Table Text Block]
Summary of Accrued Restructuring Costs
Deferred Tax Assets, Valuation Allowance
Less: valuation allowance
Deferred Tax Assets, Valuation Allowance, Total
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
U.S. federal taxes at statutory rate
Price per share
Shares Issued, Price Per Share
Fair value of common stock price per share
Subsequent Event [Line Items]
Cybersecurity Risk Management Third Party Engaged [Flag]
Documents Incorporated by Reference [Text Block]
Documents Incorporated by Reference
Goodwill
Goodwill
Goodwill, Total
Goodwill, Beginning Balance
Goodwill, Ending Balance
Effective Income Tax Rate Reconciliation, Percent
Total
Annual license maintenance fees
Annual License Maintenance Fees
Annual license maintenance fees
Investment Income, Interest
Interest income
Income Tax Jurisdiction [Axis]
Income Tax Authority
Research and Development Arrangement, Contract to Perform for Others, Description and Terms
Research terms
Summary of Income Tax Contingencies [Table Text Block]
Schedule of Reconciliation of Unrecognized Tax Benefits
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Cash, Cash Equivalents and Restricted Cash
Share based compensation arrangement by share based payment award options aggregate intrinsic value.
Share Based Compensation Arrangement By Share Based Payment Award Options Aggregate Intrinsic Value [Abstract]
Options Outstanding, Aggregate Intrinsic Value
Options and ESPP to purchase common stock
Options And E S P P To Purchase Common Stock [Member]
Options and ESPP to purchase common stock.
License agreement.
License Agreement Disclosure [Text Block]
License Agreement
Property, Plant and Equipment [Line Items]
Property Plant And Equipment [Line Items]
Supplemental information related to leases.
Supplemental Information Related To Leases Table [Text Block]
Summary of Supplemental Information Related to Leases
Vesting [Domain]
Vesting
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Options granted
Cybersecurity Risk Management, Strategy, and Governance [Table]
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Summary of Calculation of Basic and Diluted Net Income (Loss) Per Share
Furniture and Fixtures, Gross
Furniture and fixtures
Nondeductible items
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Amount [Abstract]
Estimated research service termination month and year.
Estimated Research Service Termination Month And Year
Estimated research service termination month & year
Share-Based Payment Arrangement [Member]
Options, TRSUs, PSUs and the ESPP
Disaggregation of Revenue [Table Text Block]
Schedule of Revenue by Collaboration Partners
Retirement Benefits [Text Block]
Defined Contribution Plan
Share-Based Payment Arrangement, Noncash Expense [Abstract]
Stock-based compensation expense:
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Balances, end of the period
Balances, beginning of the period
Liabilities, Current
Total current liabilities
Total current liabilities
Penalties accrued
Unrecognized Tax Benefits, Income Tax Penalties Expense
Increase (Decrease) in Accounts Receivable
Accounts receivable
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Adjustments to reconcile net income (loss) to net cash used in operating activities:
Amgen Inc.
Amgen Inc [Member]
Amgen Inc
Amgen
Domestic Tax Jurisdiction [Member]
Federal
Accounting Standards Update [Axis]
Accounting Standards Update
Future minimum lease payments
Operating Leases Future Minimun Payment
Operating Leases Future Minimun Payment
Restructuring and Related Cost, Number of Positions Eliminated, Period Percent
Percentage of company's workforce reduction
Equity, Attributable to Parent [Abstract]
Stockholders' equity (deficit)
Entity Small Business
Entity Small Business
Research and Development [Abstract]
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Increase in accumulated deficit balance
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Ending Balance
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
Stock-based compensation
Accounting Standards Update 2016-02 [Member]
ASC 842
Nature of Operations [Text Block]
Description of the Business
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Options cancelled/forfeited
Sale of Stock, Price Per Share
Price of per shares issued
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Options exercised
Aggregate intrinsic value of stock options exercised
Share-Based Payment Arrangement [Text Block]
Stock-based Compensation
Purchases of short term investments
Payments to Acquire Short-Term Investments
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Two Thousand Twenty Six Lease [Member]
Two thousand twenty six leases.
2026 Lease
Lease Contractual Term [Axis]
Leases [Abstract]
Contract with Customer, Liability
Deferred revenue
Estimated total fair value consideration recorded as deferred revenue
Contract with Customer, Liability, Total
Beginning Balance
Ending Balance
Ending Balance
Amendment Flag
Amendment Flag
Product and Service [Domain]
Product and Service
Loss Contingencies [Line Items]
Loss Contingencies [Line Items]
Common stock shares issuable under agreement.
Common Stock Shares Issuable Under Agreement
Common stock, shares issuable under agreement
Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount
U.S. federal taxes at statutory rate, amount
Number of shares issued upon warrants
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Amortized Cost
Cash Cash Equivalents And Investments Amortized Cost Basis
Cash, cash equivalents and investments, amortized cost basis.
Liabilities and Equity [Abstract]
Liabilities and Stockholders' Equity (Deficit)
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Net cash used in operating activities
Net cash used in operating activities
AbbVie Ireland Unlimited Company.
Abb Vie Ireland Unlimited Company [Member]
AbbVie Ireland Unlimited Company
AbbVie
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Common Stock [Member]
Common Stock
Cybersecurity Risk Role of Management [Text Block]
Tax Credit Carryforward, Amount
Tax credit carry forwards
Defined Contribution Plan, Employer Discretionary Contribution Amount
Company contributions to defined contribution plan
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Options granted
RSU's Awarded
Interest Receivable, Current
Lessee, Operating Lease, Liability, to be Paid, Year Three
2028
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Less: accumulated depreciation and amortization
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Estimated fair value of products.
Estimated Fair Value Of Products
Estimated fair value of products
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Research and Development Arrangement, Contract to Perform for Others, Type
Entity Address, Address Line One
Entity Address, Address Line One
Deferred Tax Liabilities, Gross
Deferred tax liabilities
Deferred Tax Liabilities, Gross, Total
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]
Change in accounting principle, accounting standards update, immaterial effect [true false]
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Schedule of Estimated Fair Value of Employee Stock Options and ESPP Using Black-Scholes Valuation Model
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV
Earnings Per Share [Abstract]
Income Tax, Policy [Policy Text Block]
Income Taxes
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag]
First target under discovery agreement.
First Target Under Discovery Agreement [Member]
First Target under Discovery Agreement
First Target under Discovery Agreement
ATM Offering
At The Market Offering [Member]
At the market offering member.
Goodwill and Intangible Assets Disclosure [Text Block]
Intangible Asset
Operating Lease, Right-of-Use Asset
Operating lease right-of-use asset
Right-of-use asset
Deferred Tax Assets, Gross
Total gross deferred income tax assets
Common stock.
Common Stock [Text Block]
Common Stock
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block]
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax, Total
Unrealized gain (loss) on available-for-sale investments, net of tax
Other comprehensive income (loss)
Class of Warrant or Right [Axis]
Document Type
Document Type
Contingent payments payable upon achieving development regulatory and commercial milestones.
Contingent Payments Payable Upon Achieving Development Regulatory And Commercial Milestones
Contingent payments payable
Goodwill and Intangible Assets, Policy [Policy Text Block]
Goodwill and Intangible Assets
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
Entity Central Index Key
Entity Central Index Key
Schedule of cash, cash equivalents, and restricted cash.
Schedule Of Cash Cash Equivalents And Restricted Cash Table [Text Block]
Schedule of Cash, Cash Equivalents, and Restricted Cash
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block]
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Excluding Exchange Rate Effect, Including Discontinued Operation
Net increase (decrease) in cash, cash equivalents and restricted cash
Subsequent Event Type [Domain]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Total potentially dilutive weighted-average outstanding shares
Total potentially dilutive weighted-average outstanding shares
Common Stock, Par or Stated Value Per Share
Common stock, par value
Accounting Standards Update [Domain]
Accounting Standards Update
Deferred Revenue Recognition Maturity Year Two
Deferred revenue recognition maturity year two.
Proceeds from issuance of pre-funded warrants and warrants, net of issuance cost
Proceeds from Issuance of Warrants
Tranche one
Share-Based Payment Arrangement, Tranche One [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Balances, end of the period
Balances, beginning of the period
Investments, Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost
Investments, Amortized Cost
Components of Deferred Tax Assets and Liabilities [Abstract]
Debt Securities, Available-for-Sale
Debt Securities, Available-for-sale, Total
Investments, Aggregate Fair Value
Document Financial Statement Error Correction [Flag]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Options exercised
Exercise of stock options, shares
Amgen other products.
Amgen Other Products [Member]
Amgen Other Products
Money market funds included in restricted cash.
Money Market Funds Included In Restricted Cash [Member]
Restricted cash (money market funds)
Restructuring and Related Cost, Expected Cost, Total
Restructuring and Related Cost, Expected Cost
Restructuring cost recorded
Accrued Liabilities, Current
Accrued liabilities
Total
Current Fiscal Year End Date
Current Fiscal Year End Date
Patent infringement lawsuit.
Patent Infringement Lawsuit [Member]
Patent Infringement Lawsuit
BVF Partners L.P.
BVF Partners L.P [Member]
BVF Partners L.P
BVF Partners
Litigation Case [Domain]
Litigation Case
Second Target Under Discovery Agreement [Member]
Second Target under Discovery Agreement
Second target under discovery agreement.
Second Target under Discovery Agreement
Entity Address, State or Province
Entity Address, State or Province
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Balance at December 31, 2024
Balance at December 31, 2025
Stock issued during period value stock options exercised and restricted stock units released.
Stock Issued During Period, Value, Stock Options Exercised and Restricted Stock Units Released
Exercise of stock options and release of RSUs
Number of targets.
Number Of Targets
Number of targets
Preferred Stock, Shares Outstanding
Convertible Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Total comprehensive loss
Comprehensive income (loss)
Total comprehensive income (loss)
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Investments, Gross Unrealized Gains
Research and Development Expense, Policy [Policy Text Block]
Research and Development Expenses
Common Stock, Capital Shares Reserved for Future Issuance
Common stock, capital shares reserved for future issuance
Total
Incremental Common Shares Attributable to Dilutive Effect of Share-Based Payment Arrangements
Stock options, ESPP & RSUs
Class of Warrant or Right [Domain]
Contract with Customer, Liability, Revenue Recognized
Deductions to deferred revenue recognized during the period
Revenue Recognized
Revenue recognized
Weighted-average pre-funded warrants
Weighted Average Number of Shares, Contingently Issuable
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount
State tax, net of federal benefit, amount
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Total Stock-based Compensation Recognized
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Amount
Other
Comprehensive Income, Policy [Policy Text Block]
Comprehensive Income (Loss)
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Schedule of Deferred Income Tax Assets and Liabilities
Schedule of Revenue by Major Customers by Reporting Segments [Table Text Block]
Schedule of Revenue and Expenses
Basic
Income (Loss) from Continuing Operations, Per Basic Share
Net income (loss) per share, Basic
Subsequent Event [Member]
Subsequent Event
Noncash lease expense.
Noncash Lease Expense
Non-cash lease expense
Non-cash lease expense
Marketable Securities, Policy [Policy Text Block]
Investments
Property, Plant and Equipment [Abstract]
Deferred Tax Assets, Tax Credit Carryforwards, Research
Research and development credits
Other Assets, Noncurrent
Other assets
Other Assets, Noncurrent, Total
Debt Securities, Available-for-Sale, Current
Short-term investments
Debt Securities, Available-for-sale, Current, Total
Antidilutive Securities [Axis]
Revenue, Product and Service [Extensible Enumeration]
Type of Revenue [Extensible List]
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Options granted generally vest percent
Basis of Presentation and Significant Accounting Policies [Text Block]
Basis of Presentation and Summary of Significant Accounting Policies
State and Local Jurisdiction [Member]
State
University of California, Santa Barbara.
University Of California Santa Barbara [Member]
UCSB
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Income/(Loss)
Finite-Lived Intangible Assets, Major Class Name [Domain]
Finite-Lived Intangible Assets, Major Class Name
Goodwill, Impairment Loss
Impairment of goodwill
Effective income Tax Reconciliation Nondeductible Expense Limitation
Effective income tax reconciliation nondeductible expense limitation.
Sec 162(m) limitation
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued, Beginning Balance
Convertible preferred stock, $0.00001 par value; 10,000,000 shares authorized and no shares issued and outstanding
Preferred Stock, Value, Issued
Preferred Stock, Value, Issued, Ending Balance
Operating loss carryforwards expiration year.
Operating Loss Carryforwards Expiration Year
Operating loss carryforwards expiration year
Deferred:
Deferred Income Tax Expense (Benefit), Continuing Operations [Abstract]
Minimum [Member]
Minimum
Minimum
Weighted average fair value per share
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Units awarded
Assets, Current [Abstract]
Current assets:
Gain (Loss) on Sale of Assets and Asset Impairment Charges
Impairment loss on machinery and equipment
Quarterly Financial Information [Text Block]
Selected Quarterly Financial Data (Unaudited)
Amortization of Intangible Assets
Amortization of intangible assets
Amortization expense of intangible assets
Amortization of Intangible Assets, Total
License payment percentage equivalence to upfront and milestone proceeds.
License Payment Percentage Equivalence To Upfront And Milestone Proceeds
Sublicense payment percentage
Segment Reporting [Abstract]
Deferred Tax Liabilities, Property, Plant and Equipment
Fixed assets
Fixed assets
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Schedule of Investments Subject to Fair Value Measurements on a Recurring Basis
Liabilities, Current [Abstract]
Current liabilities:
Termination Date
Termination date.
Termination date
Restructuring and Related Activities Disclosure [Text Block]
Restructuring
Accrued liabilities
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Accrued Liabilities
Weighted average discount rate.
Weighted Average Discount Rate [Abstract]
Weighted-average discount rate
Sublease Income
Sublease Income
Operating Loss Carryforwards, Total
Operating Loss Carryforwards
Net operating loss carryforwards
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts receivable
Accounts Receivable, after Allowance for Credit Loss, Current, Total
Jefferies.
Jefferies [Member]
Jefferies LLC
Lessee, Operating Lease, Renewal Term
Extended lease term
Number of business activities.
Number Of Business Activities
Number of business activities
Commitments and Contingencies
Commitments and contingencies (Note 10)
Lessee, Leases [Policy Text Block]
Leases
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Balance at December 31, 2024
Balance at December 31, 2025
General and Administrative Expense [Member]
General and administrative
General and Administrative Expense
Operating Lease, Liability
Present value of lease liabilities
Total operating lease liabilities
Auditor Firm Id
Auditor Firm ID
Forecast [Member]
Forecast
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value [Abstract]
Aggregate Intrinsic Value
Bristol-Myers Squibb Company.
Bristol Myers Squibb Company [Member]
Bristol Myers Squibb
Bristol Myers Squibb
Tranche Two Warrant [Member]
Tranche two warrant.
Tranche Two Warrant
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Change in valuation allowance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Outstanding, Weighted Average Remaining Contractual Terms
Balance at December 31, 2025
Capital Expenditures Incurred but Not yet Paid
Purchases of property and equipment in accounts payable and accrued liabilities
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net income (loss)
Net income (loss)
Lease Contractual Term [Domain]
Effective Income Tax Rate Reconciliation, Tax Expense (Benefit), Share-Based Payment Arrangement, Amount
Deferred tax adjustment related to stock based compensation, amount
Collaboration and license agreement.
Collaboration And License Agreement [Member]
Collaboration and License Agreement
Cybersecurity Risk Management Positions or Committees Responsible [Text Block]
Loss Contingencies [Table]
Loss Contingencies [Table]
Weighted-average common shares outstanding used to calculate basic net income (loss) per share
Weighted Average Number of Shares Outstanding, Basic
Shares used to compute net loss per share, Basic
Shares used to compute net income (loss) per share, Basic
Regeneron Pharmaceuticals, Inc member.
Regeneron Pharmaceuticals, Inc [Member]
Regeneron Pharmaceuticals, Inc
Regeneron
Scenario [Axis]
Scenario
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Ending Exercisable - December 31, 2021
Options Exercisable-December 31, 2025
Effective Income Tax Rate Reconciliation, Tax Expense (Benefit), Share-Based Payment Arrangement, Percent
Deferred tax adjustment related to stock based compensation
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Schedule of Effective Tax Rate Reconciliation
Deferred Tax Liabilities, Leasing Arrangements
Right-of-use assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Additional Disclosures [Abstract]
Weighted Average Remaining Contractual Life (years)
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Operating Leased Assets [Table]
Schedule Of Operating Leased Assets [Table]
Long-Lived Tangible Asset [Domain]
Long-Lived Tangible Asset
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block]
Gross proceeds from issuance of private placement
Proceeds from Issuance of Private Placement
Subsequent Events [Text Block]
Subsequent Event
Effective Income Tax Rate Reconciliation, Tax Credit, Percent
Effective Income Tax Rate Reconciliation, Tax Credit, Percent, Total
Tax credits
Tax credits
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
CX-801 (IFNAlpha2b).
CX-801 (IFNAlpha2b) [Member]
CX-801 (IFNAlpha2b)
Deferred Tax Asset, In-Process Research and Development
Sec 174 capitalized research and development costs
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount
Change in valuation allowance, amount
Equity, Attributable to Parent
Ending balance
Beginning balance
Total stockholders' equity (deficit)
Total stockholders' equity (deficit)
Preferred Stock, Par or Stated Value Per Share
Convertible Preferred stock, par value
Preferred stock, par value
Basis of Accounting, Policy [Policy Text Block]
Basis of Presentation
Statement of Stockholders' Equity [Abstract]
Tranche Two
Share-Based Payment Arrangement, Tranche Two [Member]
Depreciation and amortization excluding amortization of intangible assets.
Depreciation And Amortization Excluding Amortization Of Intangible Assets
Depreciation and amortization
Type of Restructuring [Domain]
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Achieving additional targets.
Achieving Additional Targets [Member]
Each Of Two Additional Targets
Collaborative Arrangement [Member]
Collaborative Arrangement
Entity Address, Address Line Two
Entity Address, Address Line Two
Fair Value Disclosures [Text Block]
Fair Value Measurements and Investments
Number of additional collaboration target.
Number Of Additional Collaboration Target
Number of additional collaboration target
Warrants and Rights Note Disclosure [Abstract]
Additional contingent payments.
Additional Contingent Payments [Member]
Additional Contingent Payments
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Number of Options
Employee stock purchase plan.
Employee Stock Purchase Plan [Member]
Employee Stock Purchase Plan
Schedule of Accrued Liabilities [Table Text Block]
Schedule of Accrued Liabilities
Share-based compensation arrangement by share-based payment award, exercise of stock options and release of restricted stock units in period.
Share-based Compensation Arrangement By Share-based Payment Award, Exercise of Stock Options and Release of Restricted Stock Units in Period
Exercise of stock options and release of RSUs, shares
Noncash Investing and Financing Items [Abstract]
Supplemental disclosures of noncash investing items:
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
Schedule of Reconciliation of Unrecognized Tax Benefits
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Regulatory approval and commercial milestone
Regulatory Approval and Commercial Milestone [Member]
Regulatory approval and commercial milestone.
Percentage of sales commission.
Percentage Of Sales Commission
Percentage of sales commission
Collaboration and License Agreements [Text Block]
Collaboration and License Agreements [Text Block]
Collaboration and License Agreements
Plan Name [Domain]
Plan Name
Astellas Pharma Inc.
Astellas Pharma Inc [Member]
Astellas Pharma Inc.
Astellas
Increase (Decrease) in Other Operating Assets
Other assets
Increase (Decrease) in Other Operating Assets, Total
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Time based restricted stock units.
Time Based Restricted Stock Units [Member]
Time based RSUs
Credit Facility [Axis]
Credit Facility
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Text Block]
Contract Termination [Member]
Contract Termination Cost
Impairment, Long-Lived Asset, Held-for-Use, Total
Impairment, Long-Lived Asset, Held-for-Use
Impairment loss related to machinery and equipment.
Impairment loss related to machinery and equipment
Impairment loss related to machinery and equipment
State
Current State and Local Tax Expense (Benefit)
Cybersecurity Risk Management Expertise of Management Responsible [Text Block]
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights
Vesting rights, description
Number of Warrants Outstanding
Class of Warrant or Right, Outstanding
Number of Warrants, Beginning
Number of Warrants, Ending
Extension of research term for each collaboration target.
Extension Of Research Term For Each Collaboration Target
Extension of research term for each collaboration target
Number of collaboration target.
Number Of Collaboration Target
Number of collaboration target
Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Maturity of operating lease liabilities
Effective Income Tax Rate Reconciliation, Other Adjustments, Amount
Other
Class of Warrant or Right [Table]
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment, net
Entity Address, City or Town
Entity Address, City or Town
Restructuring Reserve, Translation and Other Adjustment
Non-cash charges
Share based compensation arrangement by share based payment award voting rights of common stock holding percentage.
Share Based Compensation Arrangement By Share Based Payment Award Voting Rights Of Common Stock Holding Percentage
Employees holding voting rights of all classes of stock, percentage
Pre-Funded Warrant
Pre-Funded Warrant [Member]
Pre-Funded Warrant.
Stock Repurchased During Period, Shares
Stock exercised
Security Exchange Name
Security Exchange Name
Credit Facility [Domain]
Credit Facility
Indefinite-Lived Intangible Assets (Excluding Goodwill)
Intangible assets, net
Indefinite-lived Intangible Assets (Excluding Goodwill), Total
Indefinite-lived Intangible Assets (Excluding Goodwill), Beginning Balance
Indefinite-lived Intangible Assets (Excluding Goodwill), Ending Balance
Other
Effective Income Tax Rate Reconciliation, Other Adjustments, Percent
Effective Income Tax Rate Reconciliation, Other Adjustments, Percent, Total
Property, Plant and Equipment, Gross
Total property and equipment
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Ending Balance
Current:
Current Income Tax Expense (Benefit), Continuing Operations [Abstract]
Counterparty Name [Axis]
Counterparty Name
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Income/(loss) before income taxes
Income (loss) before income taxes
Accrued research and clinical current.
Accrued Research And Clinical Current
Research and clinical expenses
Antidilutive Securities, Name [Domain]
Varseta-M [Member]
Varseta-M.
Varseta-M
Deferred Tax Assets, Goodwill and Intangible Assets
Intangible assets
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Statistical Measurement [Domain]
Statistical Measurement
Exercise price of warrants
Class of Warrant or Right, Exercise Price of Warrants or Rights
Weighted-Average Exercise Price Per Share
Weighted-Average Exercise Price Per Share, Beginning
Weighted-Average Exercise Price Per Share, Ending
Assets, Current
Total current assets
Share-Based Payment Arrangement, Expense
Stock-based compensation expense
Stock-based compensation expense
Milestone payments received from revenue recognized during period.
Milestone Payments Received From Revenue Recognized During Period
Milestone payment received
Pre Clinical Candidate
Pre clinical candidate.
Pre Clinical Candidate [Member]
Document Period End Date
Document Period End Date
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV
Number of oncology target.
Number Of Oncology Target
Number of oncology target
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Options Exercisable, end of the period
Impairment of Intangible Assets, Indefinite-Lived (Excluding Goodwill)
Impairment of intangible assets
CX-2029 (CD71).
CX-2029 (CD71) [Member]
CX-2029 (CD71)
Target selection fees.
Target Selection Fees
Target selection fee
Acquired Finite-Lived Intangible Assets, Weighted Average Useful Life
Average estimated lives of patents
Statement of Financial Position [Abstract]
RSU's
Restricted Stock Units (RSUs) [Member]
Revenue [Policy Text Block]
Revenue Recognition
Antidilutive Security, Excluded EPS Calculation [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Vesting [Axis]
Vesting
Class of Stock [Axis]
Class of Stock
Deferred Tax Liabilities, Net
Net deferred income tax liabilities
Deferred Tax Liabilities, Net, Total
Total current
Current Income Tax Expense (Benefit)
Selected Quarterly Financial Information [Abstract]
Cybersecurity Risk Management, Strategy, and Governance [Line Items]
Expiration date
Warrants and Rights Outstanding, Maturity Date
Issue of Shares Warrants Exercised
Issue of shares warrants exercised.
Exercised
Other wholly owned and partnered programs.
Other Wholly Owned and Partnered Programs [Member]
Other Wholly Owned and Partnered Programs
Liabilities
Total liabilities
Total liabilities
Deferred Revenue Recognition Maturity Year
Deferred Revenue Recognition Maturity Year
Deferred revenue recognition maturity year.
Effective income tax rate reconciliation 162 (m) limitation.
Effective Income Tax Rate Reconciliation 162 (m) Limitation
Sec 162(m) limitation
Operating loss carryforwards amount to expire if not used.
Operating Loss Carryforwards Amount To Expire If Not Used
Operating loss carryforwards to expire if not utilized
Loss Contingency, Estimate of Possible Loss
Loss contingency claim amount
Lessee, Operating Lease, Liability, to be Paid, Year Two
2027
Tabular disclosure of property plant and equipment estimated useful lives.
Property Plant And Equipment Estimated Useful Lives Table [Text Block]
Schedule of Useful Lives of Property and Equipment
Finite-Lived Intangible Assets, Gross
Intangible assets, gross
Finite-Lived Intangible Assets, Gross, Total
Issuance cost
Issuance cost
Issuance cost
Weighted Average Number of Shares Outstanding, Diluted
Shares used to compute net loss per share, Diluted
Shares used to compute net income (loss) per share, Diluted
Weighted-average common shares outstanding used to calculate diluted net income (loss) per share
Securities Act File Number
Entity File Number
Total External Costs
Total external costs
External costs.
Amgen products.
Amgen Products [Member]
Amgen Products
Maturities of short term investments
Proceeds from Sale, Maturity and Collection of Short-Term Investments, Total
Proceeds from Sale, Maturity and Collection of Short-Term Investments
Cover [Abstract]
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Units forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum
Increase in number of shares available for issuance, as proportion of issued and outstanding shares of common stock, percentage
Scenario [Domain]
Scenario
US Treasury Securities [Member]
U.S.Treasury securities
Number of Operating Segments
Number of operating segments
Sale of Stock [Domain]
Sale of Stock
Segment Reporting Disclosure [Text Block]
Segment
General and Administrative Expense
General and administrative
General and Administrative Expense, Total
General and administrative expenses
Milestone payment
Milestone payment.
Milestone Payment
Milestone payment
Non-Employees Member.
Non Employees [Member]
Non-Employees
Research and Development Arrangement, Contract to Perform for Others [Line Items]
License Agreement [Line Items]
Subsequent Event [Table]
Operating Leased Assets [Line Items]
Operating Leased Assets [Line Items]
Deferred Tax Assets, Other
Other
Finite-Lived Intangible Assets, Net
Intangible assets, net
Finite-Lived Intangible Assets, Net, Beginning Balance
Finite-Lived Intangible Assets, Net, Ending Balance
Operating Lease, Expense
Rent expense
CD 71 agreement.
C D71 Agreement [Member]
CD71 Agreement
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract]
Options Outstanding, Weighted- Average Remaining Contractual Life (years)
Average Remaining Contractual Life (years)
Property, Plant and Equipment, Useful Life
Estimated useful life of property and equipment
New Accounting Pronouncements, Policy [Policy Text Block]
Adopted Accounting Pronouncements
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Schedule of Maturity of Operating Lease Liabilities
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Contract with Customer, Liability, Current
Deferred revenue, current portion
Deferred revenue, current portion
Other
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Percent
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Options granted generally vest period
Employee Severance [Member]
Severance and Benefits Costs
Performance Based Restricted Stock Units Twenty Twenty Five [Member]
Performance based restricted stock units two thousand twenty five.
2025 Performance-based RSUs
Goodwill and intangible assets.
Goodwill And Intangible Assets [Line Items]
Goodwill And Intangible Assets [Line Items]
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Depreciation
Depreciation and amortization
Depreciation, Total
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Unrecognized stock-based compensation cost
Unrecognized tax benefits,income tax penalties and interest expense,
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense, Total
Lessee, Operating Lease, Term of Contract
Initial lease term
CX-904 (EGFRxCD3) [Member]
CX-904 (EGFRxCD3) [Member]
CX-904 (EGFRxCD3)
Right to expand the number of additional collaboration target.
Right To Expand Number Of Additional Collaboration Target
Right to expand the number of additional collaboration target
Common Stock, Shares, Outstanding
Common stock, shares outstanding
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Operating Lease, Liability, Current
Operating lease liabilities - short term
Current operating lease liabilities
Premium on issuance of shares allocated to common stock.
Premium On Issuance Of Shares Allocated To Common Stock
Portion of transaction price allocated to premium on sale of common stock
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue, Remaining Performance Obligation, Amount
Revenue recognition upon performance obligation
Cybersecurity Risk Management Processes Integrated [Flag]
Document Transition Report
Document Transition Report
Operating Expenses
Total operating expenses
Accrued Liabilities, Current [Abstract]
Research and Development Expense
Research and development
Research and development expenses
Research and development expenses
Lessee, Operating Leases [Text Block]
Leases
Convertible Preferred Stock [Member]
Convertible Preferred Stock
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
Schedule of Components of Provision for Income Taxes
Statement of Cash Flows [Abstract]
Weighted Average Number of Shares Outstanding, Diluted, Adjustment [Abstract]
Effect of potentially dilutive securities:
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Weighted Average Grant Date Fair Value
Federal
Current Federal Tax Expense (Benefit)
Stock Issued During Period, Value, New Issues
Stock issued during period, value, new issues
Issuance of common stock, net of issuance costs
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Schedule of Activities Under Company's Stock Option Plans
Cash paid for amounts included in measurement of lease liabilities.
Cash Paid For Amounts Included In Measurement Of Lease Liabilities [Abstract]
Cash paid for amounts included in the measurement of lease liabilities
Performance based restricted stock units.
Performance Based Restricted Stock Units [Member]
Performance based RSUs
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent
Stock based compensation
PROBODY platform intangible asset
PROBODY platform intangible asset [Member]
Probody platform intangible asset member.
Finite-Lived Intangible Assets [Line Items]
Finite Lived Intangible Assets [Line Items]
Earnings Per Share [Text Block]
Net Income (Loss) Per Share
Shares, Issued
Ending balance, shares
Beginning balance, shares
Unrecognized Tax Benefits that Would Impact Effective Tax Rate
Unrecognized tax benefits would affect company's effective tax rate
Cybersecurity Risk Management Processes Integrated [Text Block]
Net loss
Net income (loss)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Balances at December 31, 2021
Balances at December 31, 2025
Longitude Venture Partners V, L.P [Member]
Longitude Venture Partners V, L.P.
Longitude Venture Partners V, L.P
Operating Lease, Cost
Operating lease cost
Income Tax Contingency [Line Items]
Income Tax Contingency [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Dividend yield
Laboratory equipment
Laboratory Equipment Gross
Laboratory equipment gross.
Operating Lease, Payments
Operating cash flows from operating leases
Assets [Abstract]
Assets
Restructuring Expenses
Restructuring expenses
Restructuring expenses
Risk-free interest rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Increase (Decrease) in Prepaid Expense and Other Assets
Increase (Decrease) in Prepaid Expense and Other Assets, Total
Prepaid expenses and other assets
Restructuring and Related Activities [Abstract]
Document Fiscal Year Focus
Document Fiscal Year Focus
Open Market Sale Agreement [Member]
Open market sale agreement.
Open Market Sale Agreement
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Cash flows from investing activities:
Retirement Benefits [Abstract]
Additional milestone payment received.
Additional Milestone Payment Received
Additional milestone payment received
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Drug application for CTLA-4.
Drug Application For C T L A4 [Member]
New Drug Application for CTLA-4
Research and Development Expense [Member]
Research and development
Research and Development Expense
EGFR Products.
E G F R Products [Member]
EGFR Products
Percentage of remaining maintenance fees outstanding.
Percentage Of Remaining Maintenance Fees Outstanding
Percentage of remaining maintenance fees outstanding
Accounting Standards Update 2019-12 [Member]
ASU 2019-12
Shares issued average price per share.
Shares Issued Average Price Per Share
Average price
Contract with Customer, Contract Asset, Contract Liability, and Receivable [Table Text Block]
Summary of Contract Liabilities
Federal
Deferred Federal Income Tax Expense (Benefit)
Research Tax Credit Carryforward [Member]
Research and Development Tax Credits
Restructuring Cost and Reserve [Line Items]
Revision of Prior Period [Domain]
Weighted average remaining lease term.
Weighted Average Remaining Lease Term [Abstract]
Weighted-average remaining lease term (in years)
Exercise of pre-funded warrants in period.
Exercise of Pre-funded Warrants In Period
Exercise of pre-funded warrants, shares
Securities class action lawsuit.
Securities Class Action Lawsuit [Member]
Securities Class Action Lawsuit
Unrecognized Tax Benefits [Roll Forward]
Increments of extended collaboration target research times.
Increments Of Extended Collaboration Target Research Times
Times of increments for extended collaboration target research time
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Lessee, Operating Lease, Liability, to be Paid, Year One
2026
Amgen agreement member.
Amgen Agreement [Member]
Amgen
Net Income (Loss) Available to Common Stockholders, Basic
Net income (loss) attributable to common stockholders
Net income (loss) attributable to common stockholders
Impairment, Long-Lived Asset, Held-for-Use, Statement of Income or Comprehensive Income [Extensible Enumeration]
Derivative Instrument [Axis]
Derivative Instrument
Share-Based Payment Arrangement [Abstract]
Increase in common stock capital shares reserved for future issuance
Increase in Common Stock Capital Shares Reserved For Future Issuance
Increase in common stock capital shares reserved for future issuance
Sale of Stock [Axis]
Sale of Stock
Percentage of change in ownership.
Percentage Of Change In Ownership
Percentage of change in ownership
Deferred Revenue Recognition Maturity Year One
Deferred revenue recognition maturity year one.
Revenues
Revenue
Revenues, Total
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash provided by (used in) investing activities
BVF Partners L.P. Private Placement
Private Placement [Member]
Private Placement
Title of 12(b) Security
Title of 12(b) Security
Schedule of Segment Reporting Information, by Segment [Table]
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Amount
Stock based compensation, amount
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Options cancelled/forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Units forfeited
Money Market Funds [Member]
Money market funds
Income Tax Disclosure [Text Block]
Income Taxes
Lease Commencement Date
Lease commencement date
Lease commencement date.
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Underwritten Public Offering
Underwritten Public Offering [Member]
Underwritten public offering.
Class of Warrant or Right [Line Items]
Two Thousand Sixteen Operating Lease [Member]
Two Thousand Sixteen Operating Lease Member
2016 Lease [Member]
Operating loss carryforwards amount not subject to expiration.
Operating Loss Carryforwards Amount Not Subject To Expiration
Operating loss carryforwards not subject to expiration
Weighted Average Number of Shares Issued, Basic
Weighted-average common shares outstanding
Other long-term liabilities
Other Liabilities, Noncurrent
Aggregate collaboration transaction amount.
Aggregate Collaboration Transaction Amount
Total transaction price
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities
ImmunoGen, Inc.
Immuno Gen Inc [Member]
Immuno Gen Inc
ImmunoGen, Inc [Member]
Property, Plant and Equipment [Table Text Block]
Summary of Property and Equipment, Net
Letters of Credit Outstanding, Amount
Letter of credit outstanding, amount
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Balances, end of the period
Balances, beginning of the period
Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Including Option Exercised
Proceeds from employee stock purchase plan and exercise of stock options
Proceeds, Issuance of Shares, Share-based Payment Arrangement, Including Option Exercised, Total
Income Tax Disclosure [Abstract]
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Unrecognized Tax Benefits
Balance at end of the year
Balance at the beginning of the year
Unrecognized tax benefits
Additional Paid-in Capital [Member]
Additional Paid-in Capital
Statement of Income Location, Balance [Axis]
Income Statement Location
Change in Accounting Principle, Accounting Standards Update, Adoption Date
Change in accounting principle, accounting standards update, adoption date
Trading Symbol
Trading Symbol
Intangible Asset, Finite-Lived [Table]
Schedule Of Finite Lived Intangible Assets [Table]
Property, Plant and Equipment Disclosure [Text Block]
Property and Equipment
Subsequent Event Type [Axis]
Revision of Prior Period, Adjustment [Member]
Revision of Prior Period, Adjustment
Employee-related Liabilities, Current
Payroll and related expenses
Employee-related Liabilities, Current, Total
Two thousand fifteen stock incentive plan.
Two Thousand Fifteen Stock Incentive Plan [Member]
2015 Plan
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Cash flows from financing activities:
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term (in years)
Schedule of goodwill and intangible assets.
Schedule Of Goodwill And Intangible Assets [Table]
Schedule Of Goodwill And Intangible Assets [Table]
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Accrued Liabilities
Earnings Per Share, Basic and Diluted EPS [Abstract]
Earnings per share, basic and diluted EPS.
Net income (loss) per share
Lessee, Operating Lease, Liability, to be Paid
Total lease payments
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less imputed interest
Total undiscounted lease payments
Total undiscounted lease payments
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent
California research tax credits
Research tax credits
Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate
Plan maximum percentage of eligible compensation to purchase shares
Equity Components [Axis]
Equity Components
License payment term.
License Payment Term
License payment term
Equity Component [Domain]
Equity Component
Asset Class [Axis]
Asset Class
Leasehold Improvements, Gross
Leasehold improvements
Goodwill and Intangible Assets Disclosure [Abstract]
Deferred Tax Assets, Deferred Income
Deferred revenue
Document Annual Report
Document Annual Report
Machinery and Equipment [Member]
Machinery and equipment
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Issuance of common stock under the Employee Stock Purchase Plan, shares
Number of shares issued during period
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Stock option expiration period
Effective Income Tax Rate Reconciliation, Tax Contingency, Amount
Effective Income Tax Rate Reconciliation, Tax Contingency, Amount, Total
Changes in unrecognized tax benefits
Statement of Comprehensive Income [Abstract]
Future contingent milestone payment receivable.
Contingent Milestone Payments Receivable
Contingent milestone payments receivable
Deferred tax assets lease liability.
Deferred Tax Assets Lease Liability
Lease liability
Maximum [Member]
Maximum
Statistical Measurement [Axis]
Statistical Measurement
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Options exercised
Contract with Customer, Liability, Noncurrent
Deferred revenue, net of current portion
Finite-Lived Intangible Assets, Accumulated Amortization
Less accumulated amortization
Recent accounting pronouncements.
Recent Accounting Pronouncements [Text Block]
Recent Accounting Pronouncements
Payment of upfront fees.
Payment Of Upfront Fees
Payment of upfront fees
Common Stock, Value, Issued
Common Stock, Value, Issued, Total
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Ending Balance
Common stock, $0.00001 par value; 300,000,000 and 150,000,000 shares authorized, and 170,186,365 and 80,099,889 shares issued and outstanding at December 31, 2025 and 2024, respectively
Cash and Cash Equivalents [Abstract]
Third and fourth targets.
Third And Fourth Targets [Member]
Third And Fourth Target
Income Tax Contingency [Table]
Income Tax Contingency [Table]
Deferred Tax Liabilities, Prepaid Expenses
Prepaid expenses
Diluted
Income (Loss) from Continuing Operations, Per Diluted Share
Net income (loss) per share, Diluted
Deferred Tax Assets, Operating Loss Carryforwards
Net operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Total
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]
Tax Credit Carryforward [Axis]
Tax Credit Carryforward
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Impairment of Long-Lived Assets
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
State tax, net of federal benefit
Entity Public Float
Entity Public Float
Expected volatility
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Preferred Stock, Shares Authorized
Convertible Preferred stock, shares authorized
Preferred stock, shares authorized
Proceeds from Collaborators
Upfront payment received
Finite-Lived Intangible Assets by Major Class [Axis]
Finite-Lived Intangible Assets by Major Class
Clinical Development Milestone Payment
Clinical development milestone payment
Clinical Development Milestone Payment
Estimated research service period.
Estimated Research Service Period
Estimated research service period
Deemed Dividend on Warrants
Deemed dividend on warrants.
Deemed dividend on warrants
Deemed Dividend on Warrants, Total
Deemed dividend on warrants
Entity Registrant Name
Entity Registrant Name
Entity Voluntary Filers
Entity Voluntary Filers
Other Nonoperating Income (Expense)
Other Nonoperating Income (Expense), Total
Other income (expense), net
Other income (expense)
Additional Paid in Capital
Additional paid-in capital
Additional Paid in Capital, Ending Balance
Additional Paid in Capital, Total
Additional Paid in Capital, Beginning Balance
State
Deferred State and Local Income Tax Expense (Benefit)
Subsequent Events [Abstract]
Cybersecurity Risk Management Positions or Committees Responsible [Flag]
Provision for income taxes
Provision for income taxes
Income tax expense (benefit)
Income Tax Expense (Benefit)
Income tax expense (benefit)
Loss/(Benefit) from income taxes
Computer equipment and software
Computer equipment and software.
Computer Equipment And Software [Member]
Common stock, value of shares issued in connection with agreement
Proceeds from issuance of common stock, net of issuance costs
Proceeds from issuance of common stock, net of issuance cost
Aggregate net proceeds
Other Comprehensive Income (Loss), Tax [Abstract]
Other comprehensive income (loss):
Business Combination, Contingent Consideration, Type [Axis]
Contingent Consideration by Type
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Transition Agreement [Member]
Transition agreement.
Moderna
ModernaTX, Inc [Member]
ModernaTX, Inc [Member]
ModernaTX, Inc
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentration of Credit Risk and Other Risks and Uncertainties
Accumulated other comprehensive income
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
General research and development expenses.
General Research and Development Expenses
General research and development expenses
General research and development expenses
Assets Fair Value Measurements
Assets fair value measurements.
Aggregate Fair Value
Cash payment
Payments for Restructuring
Cash payments made
Payments to Acquire Property, Plant, and Equipment
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Granted
Units awarded
Assets
Total assets
Finite-Lived Intangible Assets, Net [Abstract]
Intangible assets
Property, Plant and Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Options Exercisable, end of the period
Ending Exercisable - December 31, 2021
Restructuring Cost [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Outstanding
PSU's Awarded, Grant date fair value
Balance at December 31, 2025
Share-Based Payment Arrangement [Policy Text Block]
Stock-Based Compensation
Total deferred
Deferred Income Tax Expense (Benefit)
Sale of Stock, Number of Shares Issued in Transaction
Number of shares issued
Stock Issued During Period, Shares, New Issues
Issuance of common stock under the Open Market Sale Agreement, net of issuance cost, shares
Issuance of common stock, net of issuance costs, shares
Lease, Cost [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Units vested
Units vested
Effective Income Tax Rate Reconciliation, Percent [Abstract]
Property, Plant, and Equipment, Useful Life, Term, Description [Extensible Enumeration]
City Area Code
City Area Code
Internal Costs
Internal costs.
Internal costs
Auditor Name
Auditor Name
Restricted Cash and Cash Equivalent, Current
Restricted cash
Restricted Cash and Cash Equivalents, Current, Total
Computer equipment and software gross.
Computer Equipment And Software Gross
Computer equipment and software
Lease Agreements [Member]
New Lease Agreement
Quarterly Financial Information [Table Text Block]
Summary of Selected Quarterly Financial Data
Schedule of Intangible Assets
Schedule of Intangible Assets and Goodwill [Table Text Block]
Counterparty Name [Domain]
Counterparty Name
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount
California research tax credits, amount
Research tax credits, amount
Sublicense agreement.
Sublicense Agreement [Member]
Sublicense Agreement
Variable Lease, Cost
Variable lease cost
Stock Issued During Period, Value, Employee Stock Purchase Plan
Issuance of common stock under the Employee Stock Purchase Plan
Litigation Case [Axis]
Litigation Case
Operating Lease, Weighted Average Remaining Lease Term
Operating lease
Segment Reporting Information [Line Items]
Performance Based Restricted Stock Units Two Thousand Twenty Four [Member]
Performance Based Restricted Stock Units Twenty Twenty Four1 [Member]
2024 Performance based RSU
Accrued liabilities and other long-term liabilities
Increase decrease in accrued and other liabilities noncurrent.
Increase Decrease In Accrued And Other Liabilities Noncurrent
Lease expiration date
Lease Expiration Date
Letter of Credit [Member]
Letter of Credit
CX-2051 (EpCAM).
CX-2051 (EpCAM) [Member]
CX-2051 (EpCAM)
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Ending Balance
One Time Severance Payments and Other Employee Related Costs [Member]
One Time Severance Payments and Other Employee Related Costs [Member]
One Time Severance Payments and Other Employee Related Costs
Total
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation
Cash, cash equivalents and restricted cash, end of year
Cash, cash equivalents and restricted cash, beginning of year
Operating Income (Loss)
Loss from operations
Income (loss) from operations
Income (loss) from operations
Offering expenses
Offering Expenses
Offering expenses.
Contract with customer liability additions.
Contract With Customer Liability Additions
Additions to deferred revenue
Additions
Retained Earnings [Member]
Accumulated Deficit
Business Combination, Contingent Consideration, Type [Domain]
Contingent Consideration Type
Research and development service fees.
Research And Development Service Fees
Research and development service fees
Share-Based Compensation Arrangements by Share-Based Payment Award, Restricted Stock Units, Vested and Expected to Vest [Table Text Block]
Schedule of Company's TRSU Activities
Share-Based Payment Arrangement, Noncash Expense
Share-based Payment Arrangement, Noncash Expense, Total
Stock-based compensation expense
Stock-based compensation related to modification of awards
Payments of Stock Issuance Costs
Underwriting discounts and commissions
Exercises
Issue Of Shares Warrants Exercises
Issue of shares warrants exercises.
Exercises
Varsetatug masetecan (CX-2051)[Member]
Varsetatug masetecan (CX-2051).
Varsetatug Masetecan (CX-2051)
Early exercise of employee options.
Early Exercise Of Employee Options [Member]
Early Exercise of Employee Options
Operating Lease, Weighted Average Discount Rate, Percent
Operating lease
Operating Lease, Liability, Noncurrent
Operating lease liabilities - long term
Non-current operating lease liabilities
Fair Value, Inputs, Level 1 [Member]
Level I
Class of Stock [Line Items]
Class Of Stock [Line Items]
Disclosure Text Block [Abstract]
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Net cash provided by financing activities
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Change in accounting principle, accounting standards update, adopted [true false]
Auditor Location
Auditor Location
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
Summary of Company's Warrants
Derivative Contract [Domain]
Derivative Contract
Numerator:
Earnings Per Share Reconciliation [Abstract]
Loss Contingency, Name of Plaintiff
Name of plaintiff
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Summary of Potentially Dilutive Securities Excluded from Computation of Diluted Net Loss Per Share
Income Tax Jurisdiction [Domain]
Income Tax Authority
Entity Interactive Data Current
Entity Interactive Data Current
Schedule Of Subleasing
Schedule Of Subleasing [Table Text Block]
Schedule Of Subleasing.
Research and Development, Contract to Perform for Others [Table]
Schedule Of Research And Development Arrangement Contract To Perform For Others [Table]
Increase (Decrease) in Contract with Customer, Liability
Deferred revenue
Statement of Income Location, Balance [Domain]
Income Statement Location
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Cash flows from operating activities:
Furniture and Fixtures [Member]
Furniture and fixtures
Accretion of discounts on short-term investments
Accretion (Amortization) of Discounts and Premiums, Investments
Number of research targets selected.
Number Of Research Targets Selected
Number of research targets selected
Noncash Deemed Dividend on Warrants
Noncash deemed dividend on warrants.
Deemed dividend on warrants
Issuance of pre-funded warrants and warrants, net of issuance cost
Issuance Pre-Funded Warrants, Net Of Issuance Cost
Issuance pre-funded warrants, net of issuance cost
Contract with Customer, Asset, after Allowance for Credit Loss
Amount due from agreement
Contract with Customer, Asset, after Allowance for Credit Loss, Total
Amount due from customer
Seattle genetics agreement.
Seattle Genetics Agreement [Member]
Seattle Genetics Agreement
Entity Tax Identification Number
Entity Tax Identification Number
Share Price
Common stock, shares issuable under agreement, price per share
Clinical development milestones
Clinical Development Milestones [Member]
Clinical development milestones.
Change of estimates.
Change of Estimates
Changes in estimates
Summary Of Significant Accounting Policies [Table]
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Table]
Construction in Progress, Gross
Construction in progress
Local Phone Number
Local Phone Number
Number of targets selected.
Number Of Targets Selected
Number of targets selected
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Unrecognized compensation expense, options granted
Auditor Opinion [Text Block]
Restructuring Costs, Total
Restructuring Costs
Restructuring costs
Resructuring Charges
Interest accrued
Unrecognized Tax Benefits, Interest on Income Taxes Expense
Shares used to compute net loss per share, basic and diluted
Weighted Average Number of Shares Outstanding, Basic [Abstract]
Basic
Accounting Policies [Abstract]
Revenue
Revenue from Contract with Customer, Excluding Assessed Tax
Total revenue
Total revenue
Lessee, Operating Lease, Liability, to be Paid, Year Four
2029
Class of Stock [Domain]
Class of Stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Common shares available for grant
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Unrecognized stock-based compensation cost, period for recognition
Upfront fee received.
Upfront Fee Received
Upfront fee received
Accrued Professional Fees, Current
Legal and professional expenses
Schedule Of Stock By Class [Table]
Stock, Class of Stock [Table]
Two Thousand Nineteen Stock Incentive Plan Member.
Two Thousand Nineteen Stock Incentive Plan [Member]
2019 Plan
Collaboration target research term.
Collaboration Target Research Term
Collaboration target research term
Entity Emerging Growth Company
Entity Emerging Growth Company
Tax Credit Carryforward, Name [Domain]
Tax Credit Carryforward, Name