Document and Entity Information - USD ($) $ in Millions |
12 Months Ended | ||
|---|---|---|---|
Dec. 31, 2025 |
Mar. 05, 2026 |
Jun. 30, 2025 |
|
| Document Information [Line Items] | |||
| Document Type | 10-K | ||
| Amendment Flag | false | ||
| Document Period End Date | Dec. 31, 2025 | ||
| Document Fiscal Year Focus | 2025 | ||
| Document Fiscal Period Focus | FY | ||
| Entity Registrant Name | SYNLOGIC, INC. | ||
| Entity Central Index Key | 0001527599 | ||
| Current Fiscal Year End Date | --12-31 | ||
| Entity Well-known Seasoned Issuer | No | ||
| Entity Current Reporting Status | Yes | ||
| Entity Voluntary Filers | No | ||
| Entity Filer Category | Non-accelerated Filer | ||
| Entity Small Business | true | ||
| Entity Emerging Growth Company | false | ||
| ICFR Auditor Attestation Flag | false | ||
| Document Financial Statement Error Correction [Flag] | false | ||
| Entity Shell Company | true | ||
| Entity Common Stock, Shares Outstanding | 11,698,919 | ||
| Entity Public Float | $ 4.4 | ||
| Entity File Number | 001-37566 | ||
| Entity Incorporation, State or Country Code | DE | ||
| Entity Tax Identification Number | 26-1824804 | ||
| Entity Interactive Data Current | Yes | ||
| Entity Address, Address Line One | PO Box | ||
| Entity Address, Address Line Two | 30 | ||
| Entity Address, City or Town | Winchester | ||
| Entity Address, State or Province | MA | ||
| Entity Address, Postal Zip Code | 01890 | ||
| City Area Code | 617 | ||
| Local Phone Number | 659-2802 | ||
| Document Annual Report | true | ||
| Document Transition Report | false | ||
| Auditor Firm ID | 185 | ||
| Auditor Name | KPMG LLP | ||
| Auditor Location | Boston, Massachusetts, U.S. | ||
| Auditor Opinion | Opinion on the Consolidated Financial Statements We have audited the accompanying consolidated balance sheets of Synlogic, Inc. and subsidiaries (the Company) as of December 31, 2025 and 2024, the related consolidated statements of operations and comprehensive loss, stockholders’ equity, and cash flows for the years then ended and the related notes (collectively, the consolidated financial statements). In our opinion, the consolidated financial statements present fairly, in all material respects, the financial position of the Company as of December 31, 2025 and 2024, and the results of its operations and its cash flows for the years then ended, in conformity with U.S. generally accepted accounting principles. |
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| Documents Incorporated by Reference | DOCUMENTS INCORPORATED BY REFERENCE The following documents (or parts thereof) are incorporated by reference into the following parts of this Form 10-K: Certain information required in Part III of this Annual Report on Form 10-K is incorporated from the registrant’s definitive proxy statement for the 2026 annual meeting of stockholders to be filed pursuant to Regulation 14A with the U.S. Securities and Exchange Commission within 120 days of the registrant’s fiscal year ended December 31, 2025. |
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| Common Stock [Member] | |||
| Document Information [Line Items] | |||
| Title of 12(g) Security | Common Stock, par value $0.001 per share |