v3.25.4
Property and Equipment, Net - Schedule of Property and Equipment, Net (Detail) - USD ($)
$ in Thousands
Dec. 31, 2025
Dec. 31, 2024
Property, Plant and Equipment [Line Items]    
Property and equipment, gross $ 64,248 $ 64,730
Less: Accumulated depreciation and amortization (56,613) (53,196)
Property and equipment, net 7,635 11,534
Laboratory Equipment [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 23,852 24,468
Computer Equipment [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 4,058 3,924
Furniture and Office Equipment [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 4,523 4,523
Leasehold Improvements [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 30,954 30,954
Construction in Progress [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross $ 861 $ 861