v3.25.4
Document and Entity Information - USD ($)
12 Months Ended
Dec. 31, 2025
Mar. 06, 2026
Jun. 30, 2025
Document Information [Line Items]      
Document Type 10-K    
Amendment Flag false    
Document Period End Date Dec. 31, 2025    
Document Fiscal Year Focus 2025    
Document Fiscal Period Focus FY    
Trading Symbol MCRB    
Entity Registrant Name Seres Therapeutics, Inc.    
Entity Central Index Key 0001609809    
Entity Current Reporting Status Yes    
Current Fiscal Year End Date --12-31    
Entity Filer Category Accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag false    
Document Financial Statement Error Correction [Flag] false    
Entity Shell Company false    
Entity File Number 001-37465    
Entity Tax Identification Number 27-4326290    
Entity Address, Address Line One 101 Cambridgepark Drive    
Entity Address, City or Town Cambridge    
Entity Address, State or Province MA    
Entity Address, Postal Zip Code 02140    
City Area Code 617    
Local Phone Number 945-9626    
Entity Public Float     $ 71,941,772
Entity Common Stock Shares Outstanding   9,586,298  
Entity Incorporation, State or Country Code DE    
Document Annual Report true    
Document Transition Report false    
Entity Well Known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Interactive Data Current Yes    
Title of 12(b) Security Common stock, par value $0.001 per share    
Security Exchange Name NASDAQ    
Documents Incorporated by Reference

Portions of the registrant’s definitive Proxy Statement relating to its 2026 Annual Meeting of Stockholders to be filed with the SEC within 120 days after the end of the fiscal year ended December 31, 2025 are incorporated herein by reference in Part III.

   
Auditor Firm ID 238    
Auditor Name PricewaterhouseCoopers LLP    
Auditor Location Boston, Massachusetts    
Auditor Opinion [Text Block]

Opinions on the Financial Statements

We have audited the accompanying consolidated balance sheets of Seres Therapeutics, Inc. and its subsidiaries (the “Company”) as of December 31, 2025 and 2024, and the related consolidated statements of operations and comprehensive income (loss), of stockholders' equity (deficit) and of cash flows for each of the three years in the period ended December 31, 2025, including the related notes (collectively referred to as the “consolidated financial statements”). In our opinion, the consolidated financial statements present fairly, in all material respects, the financial position of the Company as of December 31, 2025 and 2024, and the results of its operations and its cash flows for each of the three years in the period ended December 31, 2025 in conformity with accounting principles generally accepted in the United States of America.