Related Party Transactions - Additional Information (Detail) - USD ($)	12 Months Ended
Dec. 31, 2025	Dec. 31, 2024
Related Party Transaction [Line Items]
Research and development expenses	$ 69,540,000	$ 50,328,000
Revenue not from contract with customer	0	251,000
Other receivables current	67,000	146,000
GC cell [Member] \| Research and service agreement one [Member]
Related Party Transaction [Line Items]
Research and development expenses	0	0
Accounts payable and accrued liabilities current	0	0
GC cell [Member] \| Option and license agreement for AB 201 selected product as amended [Member]
Related Party Transaction [Line Items]
Revenue not from contract with customer	0	300,000
Accounts receivable net current	0	0
GC cell [Member] \| AB two hundred and five selected product license agreement [Member]
Related Party Transaction [Line Items]
Research and development expenses reimbursed	0	100,000
Other receivables current	0	0
Receipt from the counterparty	0	700,000
GC cell [Member] \| Manufacturing agreement [Member]
Related Party Transaction [Line Items]
Research and development expenses	55,000	2,900,000
Accounts payable and accrued liabilities current	0	1,000,000
RA Capital Management, LP [Member] \| Blackbird Services Agreement [Member]
Related Party Transaction [Line Items]
Research and development expenses	0	300,000
Accounts payable and accrued liabilities current	$ 0	9,000
Agreement commencement date	Jun. 01, 2024
Agreement expirary date	Jun. 01, 2025
RA Capital Management, LP [Member] \| Carnot Services Agreement [Member]
Related Party Transaction [Line Items]
Research and development expenses	$ 31,000	15,000
Accounts payable and accrued liabilities current	$ 0	$ 15,000
Agreement commencement date	Nov. 01, 2024
Agreement expirary date	Dec. 31, 2025

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