v3.25.4
Segment - Summary of Reconciles Reported Revenues to Net (Loss) Income under Significant Expense Principle (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Research and development expenses $ 94,789 $ 60,935
General and administrative expenses 30,310 22,120
Loss from operations (125,099) (83,055)
Interest income 13,616 12,138
Change in fair value of preferred stock tranche right liability   (7,390)
Change in fair value of preferred stock tranche right liability, change 0 7,390
Provision for income taxes 0 0
Net loss (111,483) (78,307)
RAP-219 Program External Expenses    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Research and development expenses 41,144 22,080
Preclinical Programs External Expenses    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Research and development expenses 16,565 16,535
R & D Personnel-Related Costs (Including Stock-based Compensation)    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Research and development expenses 30,404 19,500
Other Costs    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
Research and development expenses 6,676 2,820
G & A Personnel Related Costs (Including Stock-based Compensation)    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
General and administrative expenses 21,519 13,989
Professional and Consulting Costs    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
General and administrative expenses 5,260 5,482
Facility Related and Other    
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]    
General and administrative expenses $ 3,531 $ 2,649