v3.25.4
Income Taxes - Additional Information (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Income Tax Disclosure [Line Items]    
Income tax expense benefit $ 0 $ 0
Unrecognized tax benefits 0 0
Tax credit carryforwards 30,714 22,784
Accrued interest or penalties 0 0
Income taxes paid 0  
Income tax refunds 0  
Research and development 145,638 83,105
Gross deferred tax assets 235,773 181,832
State [Member]    
Income Tax Disclosure [Line Items]    
Tax credit carryforwards $ 4,300  
Tax credit carryforward expiration year start 2038  
Operating loss carryforward expiration year start 2038  
State [Member] | Expirable [Member]    
Income Tax Disclosure [Line Items]    
Net operating loss carryforwards $ 419,000  
Domestic Tax Authority [Member]    
Income Tax Disclosure [Line Items]    
Net operating loss carryforwards 475,900  
Tax credit carryforwards $ 26,400  
Tax credit carryforward expiration year start 2038  
Research and development $ 191,000 131,000
Gross deferred tax assets 50,400 $ 32,400
Domestic Tax Authority [Member] | Expirable [Member]    
Income Tax Disclosure [Line Items]    
Net operating loss carryforwards 458,300  
Foreign [Member]    
Income Tax Disclosure [Line Items]    
Tax credit carryforwards $ 0  
Tax credit carryforward expiration year start 2038