v3.25.4
Significant Agreements - Alexion Option and License Agreement (Details)
$ in Thousands
1 Months Ended 12 Months Ended
Oct. 31, 2021
USD ($)
item
Dec. 31, 2025
USD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Sep. 20, 2023
item
Dec. 31, 2022
USD ($)
Mar. 04, 2022
item
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Collaboration revenue   $ 40,374 $ 80,001 $ 250,008      
Option and License Agreement              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Number of performance obligations | item             3
Number of material rights | item             3
Alexion | Option and License Agreement              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Number of performance obligations | item 2            
Number of material rights | item 2            
Upfront payment $ 30,000            
Non-refundable upfront payment received $ 30,000            
Number of license options | item 1            
Allocation of transaction price           $ 15,000  
Aggregate milestone payments, if exercise rights $ 10,000            
Deductions   $ 0 $ 0 $ 0      
Alexion | Second Material Right              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Number of days written notice required by reporting entity to terminate agreement 90 days            
Alexion | Pfizer Collaborative Arrangement              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Number of transgenes | item         2    
Alexion | Development, regulatory and commercialization milestone | Option and License Agreement              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Aggregate maximum milestone payments to be received from collaborative partner $ 115,000            
Alexion | Sales milestone | Option and License Agreement              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Aggregate maximum milestone payments to be received from collaborative partner $ 175,000