Income taxes - Additional Information (Details) - USD ($) |
12 Months Ended | |
|---|---|---|
Dec. 31, 2025 |
Dec. 31, 2024 |
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| Income Taxes [Line Items] | ||
| U.K. tax rate | 25.00% | 25.00% |
| Tax expense related to current tax | $ 11,000 | $ 845,000 |
| Deferred tax expense | 0 | |
| Deferred tax liabilities | 0 | 0 |
| SME scheme | ||
| Income Taxes [Line Items] | ||
| Tax credit | 7,500,000 | 13,200,000 |
| RDEC scheme | ||
| Income Taxes [Line Items] | ||
| Tax credit | 300,000 | |
| Collaboration Agreement with Hansoh | ||
| Income Taxes [Line Items] | ||
| Milestone payments received | $ 0 | 2,000,000 |
| Milestone payment, tax withholding | $ 200,000 | |
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- Definition Income taxes. No definition available.
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- Definition Milestone payment tax withholding. No definition available.
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- Definition Milestone payments received. No definition available.
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- Definition Amount of current income tax expense (benefit) pertaining to taxable income (loss) from continuing operations. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount of deferred income tax expense (benefit) and income tax credits. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount, after deferred tax asset, of deferred tax liability attributable to taxable differences without jurisdictional netting. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Percentage of domestic federal statutory tax rate applicable to pretax income (loss). Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition The amount of the tax credit carryforward, before tax effects, available to reduce future taxable income under enacted tax laws. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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