v3.25.4
Summary of Significant Accounting Policies - Additional Information (Details)
 12 Months Ended
Feb. 05, 2024
USD ($)
OrdinaryShare
$ / shares
shares
Dec. 31, 2025
USD ($)
Segment
Dec. 31, 2024
USD ($)
Summary Of Significant Accounting Policies [Line Items]      
Net loss   $ (88,612,000) $ (45,309,000)
Accumulated losses   562,572,000 474,044,000
Cash outflows from operating activities   (62,271,000) (67,640,000)
Cash and cash equivalents and short-term investments   $ 85,100,000  
Number of reportable segments | Segment   1  
Goodwill impairment loss   $ 0 0
Change in accounting principle, accounting standards update, adopted [true false]   true  
Change in accounting principle, accounting standards update, adoption date   Dec. 31, 2025  
Accounting standards update [extensible enumeration]   us-gaap:AccountingStandardsUpdate202309Member  
American Depositary Shares      
Summary Of Significant Accounting Policies [Line Items]      
Gross proceeds from private placement $ 120,000,000    
Open Market Sale Agreement | American Depositary Shares | Jefferies LLC      
Summary Of Significant Accounting Policies [Line Items]      
Gross proceeds from sale of stock     27,700,000
Placement agent fees and other expenses     900,000
Gross proceeds from private placement     27,700,000
Private Placement | American Depositary Shares      
Summary Of Significant Accounting Policies [Line Items]      
Placement agent fees and other expenses $ 7,700,000    
Sale of stock, number of shares issued | shares 5,714,286    
Number of ordinary shares in American Depositary Share | OrdinaryShare 3    
Sale of stock, price per share | $ / shares $ 21    
Gross proceeds from private placement $ 120,000,000    
Collaboration Agreement with AstraZeneca      
Summary Of Significant Accounting Policies [Line Items]      
Milestone payments received   $ 0 10,000,000
Collaboration Agreement with Hansoh      
Summary Of Significant Accounting Policies [Line Items]      
Milestone payments received   $ 0 $ 2,000,000
Minimum | Licenses and Software      
Summary Of Significant Accounting Policies [Line Items]      
Estimated useful lives of intangible assets   3 years  
Minimum | Furniture and Equipment      
Summary Of Significant Accounting Policies [Line Items]      
Estimated useful life of property, plant and equipment   3 years  
Maximum | Licenses and Software      
Summary Of Significant Accounting Policies [Line Items]      
Estimated useful lives of intangible assets   10 years  
Maximum | Furniture and Equipment      
Summary Of Significant Accounting Policies [Line Items]      
Estimated useful life of property, plant and equipment   10 years