v3.25.4
Segments - Schedule of Forth Disaggregated Research and Development Expenses (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Segment Reporting Information [Line Items]    
Research and development expense $ 46,713 $ 14,336
Operating Segments [Member]    
Segment Reporting Information [Line Items]    
Research and development expense 46,713 14,336
Operating Segments [Member] | Direct Expense [Member] | Budoprutug    
Segment Reporting Information [Line Items]    
Research and development expense 25,045 5,982
Operating Segments [Member] | Direct Expense [Member] | CLYM1161    
Segment Reporting Information [Line Items]    
Research and development expense [1] 11,964 0
Operating Segments [Member] | Direct Expense [Member] | Legacy programs    
Segment Reporting Information [Line Items]    
Research and development expense [2] 107 201
Operating Segments [Member] | Unallocated Expense [Member] | Personnel-related (including stock-based compensation)    
Segment Reporting Information [Line Items]    
Research and development expense 8,232 7,990
Operating Segments [Member] | Unallocated Expense [Member] | Other research and development expenses    
Segment Reporting Information [Line Items]    
Research and development expense $ 1,365 $ 163
[1] Includes the upfront payment and the associated direct transaction costs incurred in connection with the Mabworks Agreement for the year ended December 31, 2025.
[2] Includes direct expenses related to the Company's legacy product candidates ETX-123 and ETX-155.