CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
Dec. 31, 2025	Dec. 31, 2024
Cash flows used in operating activities:
Net loss	$ (144,735)	$ (301,743)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense	27,645	33,038
Depreciation expense	525	904
Accretion of investment discounts, net	(5,526)	(9,856)
Inventory impairment and loss on firm purchase commitments	0	118,680
Charge for purchase of IPR&D assets		36,203
Other non-cash items	(169)	958
Changes in operating assets and liabilities:
Accounts receivable, net	359	39,602
Inventories		(9,253)
Interest receivable	24	359
Prepaid expenses and other current assets	5,960	1,998
Operating lease right-of-use assets	1,730	1,954
Deposits and other assets	(1,976)	677
Accounts payable	580	(19,102)
Accrued expenses	(6,598)	(59,810)
Operating lease liabilities	(1,162)	(2,256)
Net cash used in operating activities	(123,343)	(167,647)
Cash flows provided by investing activities:
Purchases of property and equipment	(138)	(157)
Purchases of IPR&D assets, including transaction costs		(36,203)
Purchases of investments	(231,823)	(231,986)
Proceeds from maturities of marketable securities	246,000	344,000
Net cash provided by investing activities	14,039	75,654
Cash flows provided by financing activities:
Proceeds from financings, net of issuance costs	256,313
Proceeds from exercise of stock options and RSUs vesting	4,077	2,132
Withholding taxes paid on stock-based awards	(3,361)	(1,784)
Net cash provided by financing activities	257,029	348
Effect of exchange rate changes on cash, cash equivalents and restricted cash equivalents	1,074	(438)
Net increase (decrease) increase in cash, cash equivalents and restricted cash equivalents	148,799	(92,083)
Cash, cash equivalents and restricted cash equivalents, beginning of year	78,837	170,920
Cash, cash equivalents and restricted cash equivalents, end of year	227,636	78,837
Reconciliation of cash, cash equivalents and restricted cash equivalents:
Cash and cash equivalents	226,651	77,391
Restricted cash equivalents	985	1,446
Total cash, cash equivalents and restricted cash equivalents:	227,636	$ 78,837
Supplemental disclosure of cash flow information:
Other assets included in accounts payable and accrued expenses	500
Right-of-use assets obtained in exchange for new operating lease liabilities	$ 5,140

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