Document and Entity Information Document Type Document Annual Report Document Period End Date Document Transition Report Securities Act File Number Entity Registrant Name Entity Incorporation, State or Country Code Entity Tax Identification Number Entity Address, Address Line One Entity Address, Address Line Two Entity Address, City or Town Entity Address, State or Province Entity Address, Postal Zip Code City Area Code Local Phone Number Title of 12(b) Security Trading Symbol Security Exchange Name Entity Well-known Seasoned Issuer Entity Voluntary Filers Entity Current Reporting Status Entity Interactive Data Current Entity Filer Category Entity Small Business Entity Emerging Growth Company ICFR Auditor Attestation Flag Document Financial Statement Error Correction [Flag] Entity Shell Company Entity Public Float Entity Common Stock, Shares Outstanding Documents Incorporated by Reference [Text Block] Entity Central Index Key Current Fiscal Year End Date Document Fiscal Year Focus Document Fiscal Period Focus Amendment Flag Auditor Name Auditor Firm ID Auditor Location Balance Sheets Statement [Table] Statement [Line Items] Assets [Abstract] Assets Assets, Current [Abstract] Current assets: Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Debt Securities, Available-for-Sale, Current Marketable securities Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Amount of asset related to consideration paid in advance for current portion of prepaid research and development expense that provides economic benefits within a future period of one year or the normal operating cycle, if longer. Prepaid Research And Development Asset, Current Prepaid research and development Assets, Current Total current assets Property, Plant and Equipment, Net Property and equipment, net Total, property plant and equipment net Operating Lease, Right-of-Use Asset Right of use assets - operating leases Other Assets, Noncurrent Other assets Assets Total assets Liabilities and Equity [Abstract] Liabilities and stockholders' equity Liabilities, Current [Abstract] Current liabilities: Accounts Payable, Current Accounts payable The carrying balance as of the balance sheet of accrued expenses and other current liabilities. Accrued Expenses and Other Current Liabilities. Accrued expenses and other current liabilities Accrued expenses and other current liabilities Contract with Customer, Liability, Current Non-refundable sublicense and transition services payments Non-refundable sublicense payments received Operating Lease, Liability, Current Operating lease liabilities Liabilities, Current Total current liabilities Operating Lease, Liability, Noncurrent Operating lease liabilities - noncurrent Liabilities Total liabilities Commitments and Contingencies Commitments and contingencies (note 11) Equity, Attributable to Parent [Abstract] Stockholders' equity: Preferred Stock, Value, Issued Preferred stock, $0.0001 par value: 10,000,000 shares authorized; no shares issued and outstanding at both December 31, 2025 and December 31, 2024 Additional Paid in Capital Additional paidin capital Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive income (loss) Retained Earnings (Accumulated Deficit) Accumulated deficit Equity, Attributable to Parent Balance at end of period Balance at Beginning of period Total stockholders' equity Liabilities and Equity Total liabilities and stockholders' equity Preferred Stock, Par or Stated Value Per Share Preferred stock, par value (in dollars per share) Preferred Stock, Shares Authorized Preferred stock, shares authorized Preferred Stock, Shares Issued Preferred stock, shares issued Preferred Stock, Shares Outstanding Preferred stock, shares outstanding Common Stock, Par or Stated Value Per Share Common stock, par value (in dollars per share) Common Stock, Shares Authorized Common stock, shares authorized Common Stock, Shares, Issued Common stock, shares issued Common Stock, Shares, Outstanding Common stock, shares outstanding Statements of Operations and Comprehensive Loss Operating Expenses [Abstract] Operating expenses: Research and Development Expense Research and development Total research and development expenses General and Administrative Expense General and administrative Total general and administrative expenses Asset Impairment Charges Total impairment losses Impairment of long-lived assets Operating Income (Loss) Loss from operations Loss from operations Other Nonoperating Income (Expense) Other (income) expense, net Other income (expense), net Net loss Net loss Net loss Earnings Per Share [Abstract] Per share information: Earnings Per Share, Basic Net loss per share of common stock, basic Earnings Per Share, Diluted Net loss per share of common stock, diluted Weighted Average Number of Shares Outstanding, Basic Weighted average common shares outstanding, basic Weighted Average Number of Shares Outstanding, Diluted Weighted average common shares outstanding, diluted Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract] Comprehensive loss: OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment and Tax Unrealized gain (loss) on marketable securities Comprehensive Income (Loss), Net of Tax, Attributable to Parent Comprehensive loss Statements of Stockholders' Equity Equity Components [Axis] Equity Component [Domain] Common Stock [Member] Common stock Additional Paid-in Capital [Member] Additional paidin capital AOCI Attributable to Parent [Member] Accumulated other comprehensive income (loss) Retained Earnings [Member] Accumulated deficit Increase (Decrease) in Stockholders' Equity [Roll Forward] Stockholders' equity Shares, Outstanding Balance at end of period (in shares) Balance at Beginning of period (in shares) Stock Issued During Period, Value, New Issues Sale of common stock, net of issuance costs Issuance of common stock under the ATM Facility, net of offering costs Stock Issued During Period, Shares, New Issues Shares issued Issuance of common stock under the ATM Facility, net of offering costs (in shares) Shares Issued, Value, Share-Based Payment Arrangement, after Forfeiture Exercise of stock options and vesting of restricted stock units Shares Issued, Shares, Share-Based Payment Arrangement, after Forfeiture Exercise of stock options and vesting of restricted stock units (in shares) Stock Issued During Period, Value, Employee Stock Purchase Plan Issuance of shares in connection with employee stock purchase plan Stock Issued During Period, Shares, Employee Stock Purchase Plans Issuance of shares in connection with employee stock purchase plan (in shares) APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Sharebased compensation expense Statements of Cash Flows Net Cash Provided by (Used in) Operating Activities [Abstract] Cash flows used in operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash provided by (used in) operating activities: Depreciation, Depletion and Amortization Depreciation and amortization Depreciation and amortization expense Share-Based Payment Arrangement, Noncash Expense Sharebased compensation Amortization of Debt Discount (Premium) Amortization of premium and discount on marketable securities, net Other Noncash Expense Other non-cash items Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other current assets, and other assets The amount of increase (decrease) in prepaid research and development. Increase (Decrease) In Prepaid Research and Development Prepaid research and development Increase (Decrease) in Contract with Customer, Liability Non-refundable sublicense and transition services payments received The amount of increase (decrease) during the period in the carrying value of right of use assets and operating lease liabilities. Increase (Decrease) in Right of Use Assets and Operating Lease Liabilities Right of use assets and operating lease liabilities Increase (Decrease) in Accounts Payable, Trade Accounts payable Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities Accrued expenses and other current liabilities Net Cash Provided by (Used in) Operating Activities Net cash provided by (used in) operating activities Net Cash Provided by (Used in) Investing Activities [Abstract] Cash flows provided by (used in) investing activities: Payments to Acquire Marketable Securities Purchases of marketable securities Proceeds from Sale and Maturity of Marketable Securities Sales or maturities of marketable securities Payments to Acquire Productive Assets Purchases of property and equipment and other assets Proceeds from Sale of Productive Assets Sales of property and equipment and other assets Proceeds from Sale of Property, Plant, and Equipment Sale of property and equipment and other assets Net Cash Provided by (Used in) Investing Activities Net cash provided by (used in) investing activities Net Cash Provided by (Used in) Financing Activities [Abstract] Cash flows provided by (used in) financing activities: Proceeds from Issuance of Convertible Preferred Stock Proceeds from issuance of common stock under the ATM Facility, net of offering costs Proceeds from Stock Options Exercised Proceeds from the exercise of stock options Proceeds from Stock Plans Proceeds from the issuance of common stock under employee stock purchase plan Net Cash Provided by (Used in) Financing Activities Net cash provided by (used in) financing activities Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Net increase (decrease) in cash and cash equivalents Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents Cash and cash equivalents at end of year Cash and cash equivalents at beginning of year Supplemental Cash Flow Information [Abstract] Supplemental disclosure of noncash activities: Marketable Security, Unrealized Gain (Loss) Unrealized gain (loss) on marketable securities Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Right of use assets recognized upon the commencement of sublease The amount of lease liabilities recognized upon adoption of standard. Operating Lease Liability Recognized Upon Adoption of Standard Operating lease liabilities recognized upon the commencement of sublease Nature of Operations Nature of Operations [Text Block] Nature of Operations No definition available. Risks and Liquidity The entire disclosure of information pertaining to risk and liquidity. Risks And Liquidity [Text Block] Risks and Liquidity Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies No definition available. Cash, Cash Equivalents, and Marketable Securities Cash, Cash Equivalents, and Marketable Securities [Text Block] Cash, Cash Equivalents, and Marketable Securities Fair Value of Financial Instruments and Non-Financial Instruments Fair Value Disclosures [Text Block] Fair Value of Financial Instruments and Non-Financial Instruments Property and Equipment, Net Property, Plant and Equipment Disclosure [Text Block] Property and Equipment, Net Accrued Expenses and Other Current Liabilities The entire disclosure of information pertaining to accrued expenses and other current liabilities. Accrued Expenses And Other Current Liabilities Disclosure [Text Block] Accrued Expenses and Other Current Liabilities No definition available. Gemma License Agreement Collaborative Arrangement Disclosure [Text Block] Gemma License Agreement Severance Restructuring and Related Activities Disclosure [Text Block] Severance Leases Lessee, Operating Leases [Text Block] Leases Commitments and Contingencies. Commitments and Contingencies Disclosure [Text Block] Commitments and Contingencies Common Stock. Equity [Text Block] Common Stock Share-Based Compensation Share-Based Payment Arrangement [Text Block] Share-Based Compensation Income Taxes Income Tax Disclosure [Text Block] Income Taxes Segment Reporting Segment Reporting Disclosure [Text Block] Segment Reporting Subsequent Events. Subsequent Events [Text Block] Subsequent Events Disclosure of accounting policy for basis of presentation. Basis Of Presentation [Policy Text Block] Basis of Presentation Use of Estimates, Policy [Policy Text Block] Use of Estimates Fair Value of Financial Instruments, Policy [Policy Text Block] Fair Value of Financial Instruments Concentration Risk, Credit Risk, Policy [Policy Text Block] Concentration of Credit Risk Cash and Cash Equivalents, Policy [Policy Text Block] Cash and Cash Equivalents Marketable Securities, Policy [Policy Text Block] Marketable Securities Property, Plant and Equipment, Policy [Policy Text Block] Property and Equipment, Net Lessee, Leases [Policy Text Block] Leasing Research and Development Expense, Policy [Policy Text Block] Research and Development Disclosure of accounting policy for other income or other expense items. Other Income and Other Expense Policy [Policy Text Block] Other Income (Expense), Net Share-Based Payment Arrangement [Policy Text Block] Share-Based Compensation Revenue from Contract with Customer [Policy Text Block] License and Other Revenue Income Tax, Policy [Policy Text Block] Income Taxes Earnings Per Share, Policy [Policy Text Block] Net Loss Per Share New Accounting Pronouncements, Policy [Policy Text Block] Recently Issued Accounting Pronouncements Not Yet Adopted and Recently Adopted Accounting Pronouncements Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Schedule of antidilutive securities excluded from computation of earnings per share Schedule of Cash and Cash Equivalents [Table Text Block] Schedule of details regarding the Company's portfolio of cash and cash equivalents Schedule of Available-for-Sale Securities Reconciliation [Table Text Block] Schedule of details regarding the Company's portfolio of marketable securities Fair Value Measurements, Recurring and Nonrecurring [Table Text Block] Summary of assets measured at fair value on a recurring basis Fair Value Measurements, Nonrecurring [Table Text Block] Summary of non-financial instruments measured at fair value, on a nonrecurring basis Property, Plant and Equipment [Table Text Block] Schedule of property and equipment, net