v3.25.4
Leases (Details)
$ in Thousands
 1 Months Ended 12 Months Ended
Sep. 04, 2024
USD ($)
ft²
Feb. 20, 2024
USD ($)
ft²
Sep. 29, 2023
USD ($)
ft²
Aug. 07, 2023
USD ($)
ft²
Jan. 31, 2025
Dec. 31, 2025
USD ($)
ft²
item
Dec. 31, 2024
USD ($)
Lessee, Lease, Description [Line Items]              
Sublease Income           $ 1,467 $ 987
Impairment of long-lived assets           6,145 5,233
Impairment expenses for right of use assets           2,633 2,516
Impairment expenses for property and equipment           3,373 2,279
Impairment of certain other assets             438
Future minimum lease payments              
2026           3,757  
2027           3,863  
2028           3,973  
2029           4,085  
2030           4,200  
Thereafter           17,421  
Total undiscounted lease payments           37,299  
Less: imputed interest           (13,289)  
Total lease liabilities           $ 24,010  
Employee Severance              
Lessee, Lease, Description [Line Items]              
Number of positions eliminated, period percent         55.00%    
Operating leases for office space              
Lessee, Lease, Description [Line Items]              
Area leased | ft²           37,000  
Option to extend lease           true  
Number of extension terms | item           2  
Renewal term of lease           5 years  
Option to terminate lease           true  
Notice Period for termination lease           15 months  
Sublease Agreement A              
Lessee, Lease, Description [Line Items]              
Area leased | ft²       8,000      
Option to extend lease       true      
Sublease Income       $ 100      
Annual increase in sublease rent (as a percent)       2.75%      
Sublease Agreement B              
Lessee, Lease, Description [Line Items]              
Area leased | ft²     29,000        
Option to extend lease     true        
Sublease Income     $ 900        
1835 market street sublease agreement              
Lessee, Lease, Description [Line Items]              
Area leased | ft²   16,000          
Option to extend lease   true          
Sublease Income   $ 300          
Term of Contract   18 months          
Operating leases for laboratory space              
Lessee, Lease, Description [Line Items]              
Option to terminate lease           true  
Notice Period for termination lease           12 months  
Sublease Agreement C              
Lessee, Lease, Description [Line Items]              
Area Subleased | ft² 3,200            
Subleased area of land 5.00%            
Area leased | ft² 62,000            
Sublease Income $ 100            
Annual increase in sublease rent (as a percent) 2.50%            
Impairment of long-lived assets           $ 3,500 5,200
Impairment expenses for right of use assets           2,600 2,500
Impairment expenses for property and equipment             2,300
Impairment of certain other assets             $ 400
Impairment of leasehold improvements           $ 900  
Maximum | Operating leases for laboratory space              
Lessee, Lease, Description [Line Items]              
Number of extension terms | item           2  
Extended term of new lease agreement           5 years