v3.25.4
Consolidated Statements of Stockholders’ Equity (Deficit) - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid In Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2022   56,260,570      
Beginning balance at Dec. 31, 2022 $ 18,499 $ 1 $ 516,129 $ (337) $ (497,294)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock in connection with the incentive equity plan (in shares)   950,051      
Issuance of common stock in connection with the incentive equity plan 224   224    
Issuance of common stock in connection with Symatese Europe Agreement (in shares)   610,000      
Issuance of common stock in connection with Symatese Europe Agreement 5,905   5,905    
Stock-based compensation 16,458   16,458    
Net loss (61,685)       (61,685)
Other comprehensive income (loss) (90)     (90)  
Ending balance (in shares) at Dec. 31, 2023   57,820,621      
Ending balance at Dec. 31, 2023 (20,689) $ 1 538,716 (427) (558,979)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock in connection with the incentive equity plan (in shares)   1,804,827      
Issuance of common stock in connection with the incentive equity plan 3,892   3,892    
Issuance of common stock upon follow-on offering, net of issuance costs (in shares)   3,872,100      
Issuance of common stock upon follow-on offering, net of issuance costs 50,963   50,963    
Stock-based compensation 22,254   22,254    
Net loss (50,420)       (50,420)
Other comprehensive income (loss) $ (478)     (478)  
Ending balance (in shares) at Dec. 31, 2024 63,497,548 63,497,548      
Ending balance at Dec. 31, 2024 $ 5,522 $ 1 615,825 (905) (609,399)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock in connection with the incentive equity plan and ESPP (in shares)   1,510,635      
Issuance of common stock in connection with the incentive equity plan and ESPP 1,468   1,468    
Stock-based compensation 20,796   20,796    
Net loss (51,641)        
Other comprehensive income (loss) $ 749     749  
Ending balance (in shares) at Dec. 31, 2025 65,008,183 65,008,183      
Ending balance at Dec. 31, 2025 $ (23,106) $ 1 $ 638,089 $ (156) $ (661,040)