v3.25.4
Segments of Business and Geographic Areas - Sales by Segment of Business (Details)
$ in Millions
12 Months Ended
Dec. 28, 2025
USD ($)
segment
Dec. 29, 2024
USD ($)
Dec. 31, 2023
USD ($)
Segment Reporting Information [Line Items]      
Number of segments | segment 2    
Sales to Customers $ 94,193 $ 88,821 $ 85,159
% Change 6.00% 4.30%  
Innovative Medicine      
Segment Reporting Information [Line Items]      
Sales to Customers $ 60,401 $ 56,964 54,759
% Change 6.00% 4.00%  
Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 15,728 $ 17,828 18,052
% Change (11.80%) (1.20%)  
Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,241 $ 3,396 4,418
% Change (4.60%) (23.10%)  
Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 7,837 $ 7,115 7,140
% Change 10.10% (0.40%)  
Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 25,380 $ 20,781 17,661
% Change 22.10% 17.70%  
Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 4,437 $ 4,282 3,815
% Change 3.60% 12.30%  
Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,778 $ 3,562 3,671
% Change 6.10% (3.00%)  
MedTech      
Segment Reporting Information [Line Items]      
Sales to Customers $ 33,792 $ 31,857 30,400
% Change 6.10% 4.80%  
MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 8,928 $ 7,707 6,350
% Change 15.80% 21.40%  
MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 9,258 $ 9,158 8,942
% Change 1.10% 2.40%  
MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 10,137 $ 9,845 10,037
% Change 3.00% (1.90%)  
MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,468 $ 5,146 5,072
% Change 6.30% 1.50%  
CARVYKTI | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,887 $ 963 500
% Change 95.90% 92.70%  
DARZALEX | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 14,351 $ 11,670 9,744
% Change 23.00% 19.80%  
ERLEADA | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,574 $ 2,999 2,387
% Change 19.20% 25.60%  
IMBRUVICA | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,823 $ 3,038 3,264
% Change (7.10%) (6.90%)  
RYBREVANT/LAZCLUZE | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 734 $ 327 93
TALVEY | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 463 287 63
% Change 61.30%    
TECVAYLI | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 670 $ 549 395
% Change 22.10% 38.80%  
ZYTIGA/abiraterone acetate | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 502 $ 631 887
% Change (20.40%) (28.80%)  
Other Oncology | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 376 $ 317 328
% Change 18.50% (3.40%)  
Remicade | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,768 $ 1,605 1,839
% Change 10.20% (12.80%)  
Simponi/Simponi Aria | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,668 $ 2,190 2,197
% Change 21.80% (0.30%)  
Stelara | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 6,078 $ 10,361 10,858
% Change (41.30%) (4.60%)  
Tremfya | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,155 $ 3,670 3,147
% Change 40.50% 16.60%  
Other Immunology | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 61 $ 3 11
% Change   (74.10%)  
CAPLYTA | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers 700 $ 0 0
% Change   0.00%  
CONCERTA/Methylphenidate | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 584 $ 641 783
% Change (9.00%) (18.10%)  
INVEGA SUSTENNA/XEPLION/TRINZA/TREVICTA | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,810 $ 4,222 4,115
% Change (9.80%) 2.60%  
SPRAVATO | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,696 $ 1,077 689
% Change 57.40% 56.40%  
OTHER NEUROSCIENCE | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,048 $ 1,175 1,553
% Change (10.90%) (24.30%)  
OPSUMIT | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,325 $ 2,225 1,973
% Change 4.50% 12.80%  
UPTRAVI | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,902 $ 1,817 1,582
% Change 4.70% 14.90%  
Other Pulmonary Hypertension | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 209 $ 240 260
% Change (12.70%) (7.70%)  
EDURANT/rilpivirine | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,486 $ 1,272 1,150
% Change 16.90% 10.60%  
PREZISTA/PREZCOBIX/REZOLSTA/SYMTUZA | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,579 $ 1,712 1,854
% Change (7.70%) (7.70%)  
Other Infectious Diseases | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 175 $ 412 1,414
% Change (57.50%)    
XARELTO | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,633 $ 2,373 2,365
% Change 11.00% 0.30%  
Other | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,145 $ 1,189 1,306
% Change (3.70%) (8.90%)  
ELECTROPHYSIOLOGY | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,634 $ 5,267 4,688
% Change 7.00% 12.30%  
Abiomed | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,751 $ 1,496 1,306
% Change 17.10% 14.50%  
Shockwave Medical, Inc. | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,146 $ 564 0
other cardiovascular | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 397 $ 380 356
% Change 4.30% 6.90%  
HIPS | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,674 $ 1,638 1,560
% Change 2.10% 5.00%  
KNEES | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,587 $ 1,545 1,456
% Change 2.70% 6.10%  
TRAUMA | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,146 $ 3,049 2,979
% Change 3.20% 2.30%  
SPINE,SPORTS & OTHER | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,852 $ 2,926 2,947
% Change (2.50%) (0.70%)  
ADVANCED | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 4,577 $ 4,488 4,671
% Change 2.00% (3.90%)  
GENERAL | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,560 $ 5,358 5,366
% Change 3.80% (0.20%)  
CONTACT LENSES/OTHER | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,910 $ 3,733 3,702
% Change 4.80% 0.80%  
SURGICAL | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,558 $ 1,413 1,370
% Change 10.20% 3.20%  
United States      
Segment Reporting Information [Line Items]      
Sales to Customers $ 53,752 $ 50,302 46,444
% Change 6.90% 8.30%  
United States | Innovative Medicine      
Segment Reporting Information [Line Items]      
Sales to Customers $ 36,344 $ 33,970 31,169
% Change 7.00% 9.00%  
United States | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 9,872 $ 11,355 11,539
% Change (13.10%) (1.60%)  
United States | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,264 $ 1,354 1,500
% Change (6.60%) (9.80%)  
United States | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,151 $ 4,398 4,065
% Change 17.10% 8.20%  
United States | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 13,659 $ 10,854 8,462
% Change 25.80% 28.30%  
United States | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,223 $ 3,143 2,697
% Change 2.60% 16.50%  
United States | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,175 $ 2,866 2,906
% Change 10.80% (1.40%)  
United States | MedTech      
Segment Reporting Information [Line Items]      
Sales to Customers $ 17,408 $ 16,332 15,275
% Change 6.60% 6.90%  
United States | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,305 $ 4,513 3,633
% Change 17.50% 24.20%  
United States | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,720 $ 5,689 5,525
% Change 0.50% 3.00%  
United States | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 4,157 $ 4,003 4,031
% Change 3.90% (0.70%)  
United States | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,225 $ 2,128 2,086
% Change 4.60% 2.00%  
United States | CARVYKTI | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,492 $ 869 469
% Change 71.60% 85.20%  
United States | DARZALEX | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 8,266 $ 6,588 5,277
% Change 25.50% 24.80%  
United States | ERLEADA | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,453 $ 1,282 1,065
% Change 13.40% 20.30%  
United States | IMBRUVICA | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 892 $ 1,020 1,051
% Change (12.50%) (3.00%)  
United States | RYBREVANT/LAZCLUZE | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 534 $ 257 66
United States | TALVEY | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 340 241 56
% Change 40.90%    
United States | TECVAYLI | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 444 $ 418 334
% Change 6.30% 25.30%  
United States | ZYTIGA/abiraterone acetate | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 23 $ 34 50
% Change (33.20%) (32.20%)  
United States | Other Oncology | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 214 $ 145 93
% Change 47.50% 55.90%  
United States | Remicade | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,171 $ 1,009 1,143
% Change 16.00% (11.70%)  
United States | Simponi/Simponi Aria | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,193 $ 1,082 1,124
% Change 10.30% (3.80%)  
United States | Stelara | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,847 $ 6,720 6,966
% Change (42.70%) (3.50%)  
United States | Tremfya | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,529 $ 2,443 2,147
% Change 44.50% 13.70%  
United States | Other Immunology | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 59 $ 3 11
% Change   (74.10%)  
United States | CAPLYTA | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers 700 $ 0 0
% Change   0.00%  
United States | CONCERTA/Methylphenidate | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 82 $ 134 230
% Change (38.60%) (41.70%)  
United States | INVEGA SUSTENNA/XEPLION/TRINZA/TREVICTA | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,725 $ 3,125 2,897
% Change (12.80%) 7.90%  
United States | SPRAVATO | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,485 $ 929 589
% Change 59.90% 57.80%  
United States | OTHER NEUROSCIENCE | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 159 $ 210 349
% Change (24.50%) (39.80%)  
United States | OPSUMIT | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,633 $ 1,557 1,292
% Change 4.80% 20.50%  
United States | UPTRAVI | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,536 $ 1,511 1,326
% Change 1.70% 13.90%  
United States | Other Pulmonary Hypertension | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 54 $ 75 79
% Change (27.00%) (5.10%)  
United States | EDURANT/rilpivirine | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 26 $ 31 35
% Change (18.40%) (10.00%)  
United States | PREZISTA/PREZCOBIX/REZOLSTA/SYMTUZA | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,226 $ 1,311 1,446
% Change (6.50%) (9.40%)  
United States | Other Infectious Diseases | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 12 $ 11 19
% Change 6.60% (41.00%)  
United States | XARELTO | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,633 $ 2,373 2,365
% Change 11.00% 0.30%  
United States | Other | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 542 $ 494 541
% Change 9.80% (8.80%)  
United States | ELECTROPHYSIOLOGY | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,891 $ 2,738 2,458
% Change 5.60% 11.40%  
United States | Abiomed | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,393 $ 1,213 1,066
% Change 14.90% 13.70%  
United States | Shockwave Medical, Inc. | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 897 $ 442 0
United States | other cardiovascular | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 124 $ 120 109
% Change 3.10% 10.70%  
United States | HIPS | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,080 $ 1,057 996
% Change 2.10% 6.20%  
United States | KNEES | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 924 $ 922 896
% Change 0.20% 2.90%  
United States | TRAUMA | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,058 $ 2,013 1,949
% Change 2.20% 3.30%  
United States | SPINE,SPORTS & OTHER | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,658 $ 1,696 1,684
% Change (2.20%) 0.70%  
United States | ADVANCED | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,900 $ 1,838 1,833
% Change 3.40% 0.20%  
United States | GENERAL | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,258 $ 2,165 2,198
% Change 4.30% (1.50%)  
United States | CONTACT LENSES/OTHER | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,754 $ 1,684 1,626
% Change 4.10% 3.60%  
United States | SURGICAL | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 471 $ 444 460
% Change 6.10% (3.40%)  
Non-US      
Segment Reporting Information [Line Items]      
Sales to Customers $ 40,441 $ 38,519 38,715
% Change 5.00% (0.50%)  
Non-US | Innovative Medicine      
Segment Reporting Information [Line Items]      
Sales to Customers $ 24,057 $ 22,994 23,590
% Change 4.60% (2.50%)  
Non-US | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,856 $ 6,473 6,513
% Change (9.50%) (0.60%)  
Non-US | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,977 $ 2,042 2,918
% Change (3.20%) (30.00%)  
Non-US | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,686 $ 2,718 3,076
% Change (1.20%) (11.60%)  
Non-US | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 11,721 $ 9,926 9,199
% Change 18.10% 7.90%  
Non-US | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,214 $ 1,140 1,117
% Change 6.50% 2.00%  
Non-US | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 603 $ 696 765
% Change (13.30%) (9.10%)  
Non-US | MedTech      
Segment Reporting Information [Line Items]      
Sales to Customers $ 16,384 $ 15,525 15,125
% Change 5.50% 2.60%  
Non-US | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,623 $ 3,194 2,717
% Change 13.40% 17.60%  
Non-US | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,538 $ 3,470 3,417
% Change 2.00% 1.50%  
Non-US | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,980 $ 5,842 6,006
% Change 2.40% (2.70%)  
Non-US | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,243 $ 3,018 2,986
% Change 7.40% 1.10%  
Non-US | CARVYKTI | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 395 $ 94 30
Non-US | DARZALEX | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 6,085 $ 5,082 4,467
% Change 19.70% 13.80%  
Non-US | ERLEADA | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,121 $ 1,717 1,322
% Change 23.50% 29.80%  
Non-US | IMBRUVICA | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,931 $ 2,018 2,214
% Change (4.30%) (8.80%)  
Non-US | RYBREVANT/LAZCLUZE | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 200 $ 70 27
Non-US | TALVEY | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers 123 46 7
Non-US | TECVAYLI | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 226 131 61
% Change 72.80%    
Non-US | ZYTIGA/abiraterone acetate | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 480 $ 597 837
% Change (19.70%) (28.60%)  
Non-US | Other Oncology | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 162 $ 172 235
% Change (6.00%) (26.80%)  
Non-US | Remicade | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 523 $ 497 549
% Change 5.30% (9.50%)  
Non-US | Simponi/Simponi Aria | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,475 $ 1,108 1,073
% Change 33.10% 3.30%  
Non-US | Stelara | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,230 $ 3,641 3,892
% Change (38.70%) (6.40%)  
Non-US | Tremfya | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,626 $ 1,227 999
% Change 32.50% 22.80%  
Non-US | Other Immunology | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2 $ 0 0
% Change   0.00%  
Non-US | CAPLYTA | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 0 $ 0 0
% Change 0.00% 0.00%  
Non-US | CONCERTA/Methylphenidate | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 502 $ 507 554
% Change (1.20%) (8.40%)  
Non-US | INVEGA SUSTENNA/XEPLION/TRINZA/TREVICTA | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,085 $ 1,097 1,218
% Change (1.10%) (9.90%)  
Non-US | SPRAVATO | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 210 $ 148 100
% Change 41.90% 48.20%  
Non-US | OTHER NEUROSCIENCE | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 889 $ 965 1,204
% Change (7.90%) (19.80%)  
Non-US | OPSUMIT | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 692 $ 668 681
% Change 3.70% (1.90%)  
Non-US | UPTRAVI | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 366 $ 307 255
% Change 19.40% 20.10%  
Non-US | Other Pulmonary Hypertension | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 155 $ 165 182
% Change (6.20%) (9.30%)  
Non-US | EDURANT/rilpivirine | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,461 $ 1,241 1,115
% Change 17.70% 11.20%  
Non-US | PREZISTA/PREZCOBIX/REZOLSTA/SYMTUZA | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 353 $ 401 408
% Change (11.90%) (1.70%)  
Non-US | Other Infectious Diseases | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 163 $ 401 1,395
% Change (59.30%)    
Non-US | XARELTO | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 0 $ 0 0
% Change 0.00% 0.00%  
Non-US | Other | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 603 $ 696 765
% Change (13.30%) (9.10%)  
Non-US | ELECTROPHYSIOLOGY | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,743 $ 2,529 2,230
% Change 8.50% 13.40%  
Non-US | Abiomed | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 358 $ 284 240
% Change 26.40% 18.20%  
Non-US | Shockwave Medical, Inc. | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 249 $ 122 0
Non-US | other cardiovascular | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 273 $ 260 247
% Change 4.90% 5.30%  
Non-US | HIPS | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 594 $ 581 564
% Change 2.20% 3.00%  
Non-US | KNEES | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 663 $ 623 559
% Change 6.50% 11.30%  
Non-US | TRAUMA | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,088 $ 1,036 1,030
% Change 5.00% 0.60%  
Non-US | SPINE,SPORTS & OTHER | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,193 $ 1,230 1,263
% Change (3.00%) (2.60%)  
Non-US | ADVANCED | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,678 $ 2,650 2,837
% Change 1.00% (6.60%)  
Non-US | GENERAL | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,302 $ 3,192 3,168
% Change 3.40% 0.80%  
Non-US | CONTACT LENSES/OTHER | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,157 $ 2,049 2,076
% Change 5.30% (1.30%)  
Non-US | SURGICAL | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,086 $ 969 910
% Change 12.10% 6.50%  
UNITED STATES Exports | Remicade | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 74 $ 98 $ 147
% Change (24.80%) (33.00%)