v3.25.4
Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($)
 1 Months Ended 3 Months Ended 9 Months Ended
Mar. 25, 2025
Aug. 05, 2024
May 13, 2024
May 08, 2024
Sep. 30, 2025
Dec. 31, 2025
Dec. 31, 2025
Dec. 31, 2024
Mar. 31, 2025
Summary Of Significant Accounting Policies [Line Items]                  
Cash and cash equivalents           $ 4,288,000 $ 4,288,000 $ 1,161,000 $ 11,312,000
Restricted cash           143,000 143,000 143,000 143,000
Accumulated deficit           (350,236,000) (350,236,000)   (342,157,000)
Cash flow from operations             8,589,000 7,426,000  
Total current assets           6,041,000 6,041,000   12,131,000
Total current liabilities           2,475,000 2,475,000   $ 3,737,000
Working capital           $ 3,500,000 $ 3,500,000    
Issuance of common stock           2,607,962 2,607,962   1,898,068
Escrow receivable           $ 0 $ 0   $ 1,000,000
Period of escrow 15 months                
Escrow receivable           1,011,000 1,011,000   0
Initial offering date       May 8, 2024          
Insurance premium financing liability           235,000 235,000   128,000
Dilutive effect             $ 0 $ 0  
Common stock equivalents excluded from computing diluted net loss per share             800,000 800,000  
Insurance Premium Financing Liability [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Insurance premium financing agreement description             In September 2025, the Company entered into an insurance premium financing agreement for $0.4 million, with a term of nine months and an annual interest rate of 7.82%. The Company made a down payment of 10% and is required to make monthly principal and interest payments of $40,468 over the term of the agreement, which will mature in June 2026.    
Financing agreement amount         $ 400,000        
Annual interest rate         7.82%        
Percentage of down payment         10.00%        
Monthly principal and interest payments         $ 40,468        
Prepaid insurance included in prepaid expenses and other current assets           $ 300,000 $ 300,000   200,000
Common Warrants [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Issuance of common stock       416,666          
Issuance of warrants   130,202   130,202          
Stock offering price per share   $ 9.6   $ 9.6          
Pre-Funded Warrants [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Stock offering price per share   $ 9.588   $ 9.588          
At-The-Market Facility [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Issuance of common stock           701,729 701,729    
Net proceeds from issuance of offerings             $ 1,800,000    
Issuance of common stock           0 701,729    
Public Offering [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Net proceeds from issuance of offerings     $ 4,500,000            
Issuance of common stock       130,202          
Public Offering [Member] | Common Warrants [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Issuance of common stock   416,666              
Public Offering [Member] | Common Warrants [Member] | Maximum [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Issuance of warrants   416,666   416,666          
Metacrine, Inc. [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Upfront payment $ 10,000,000                
Closing upfront payment 9,000,000                
Escrow receivable 1,000,000                
Metacrine's FXR Program [Member] | Maximum [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Future milestone             $ 50,000,000    
Metacrine's FXR Program [Member] | Metacrine, Inc. [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Upfront payment 10,000,000                
Closing upfront payment 9,000,000                
Escrow receivable                 $ 1,000,000
Future milestone $ 50,000,000