v3.25.4
INCOME TAXES - Schedule of Effective Income Tax Rate Reconciliation (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Earnings/(Loss) before income taxes:      
U.S. $ (19) $ (14,893) $ 2,624
Non-U.S. 9,347 6,514 5,816
Earnings/(Loss) before income taxes 9,328 (8,379) 8,440
Effective Income Tax Rate Reconciliation, Amount      
U.S. Federal statutory rate 1,959 (1,759) 1,772
GILTI 228 501 223
FDII deduction (170)    
Statutory tax rate difference between Switzerland, Ireland and other foreign jurisdictions and the U.S.   (302) (850)
Other 247    
U.S. Federal research-based credits (152) (291) (243)
Changes in valuation allowances 84 46 (171)
Nondeductible R&D charges 290 2,538 0
Changes in unrecognized tax benefits 146 (459) 143
State and local taxes 43 (25) 92
Income tax provision $ 2,272 $ 554 $ 400
Effective Income Tax Rate Reconciliation, Percent      
U.S. Federal statutory rate 21.00% 21.00% 21.00%
GILTI 2.40% (6.00%) 2.60%
FDII deduction (1.80%)    
Statutory tax rate difference between Switzerland, Ireland and other foreign jurisdictions and the U.S.   3.60% (10.10%)
Other 2.70%    
U.S. Federal research-based credits (1.60%) 3.50% (2.90%)
Changes in valuation allowances 0.90% (0.50%) (2.00%)
Nondeductible R&D charges 3.10% (30.30%) 0.00%
Changes in unrecognized tax benefits 1.60% 5.50% 1.70%
State and local taxes 0.50% 0.30% 1.10%
Income tax provision 24.40% (6.60%) 4.70%
Switzerland      
Effective Income Tax Rate Reconciliation, Amount      
Statutory tax rate difference between Switzerland, Ireland and other foreign jurisdictions and the U.S. $ (565)    
Canton 284    
Pillar Two 24    
Withholding Tax 87    
Other $ (11)    
Effective Income Tax Rate Reconciliation, Percent      
Statutory tax rate difference between Switzerland, Ireland and other foreign jurisdictions and the U.S. (6.10%)    
Canton 3.00%    
Pillar Two 0.30%    
Withholding Tax 0.90%    
Other (0.10%)    
Ireland      
Effective Income Tax Rate Reconciliation, Amount      
Statutory tax rate difference between Switzerland, Ireland and other foreign jurisdictions and the U.S. $ (390)    
Pillar Two 37    
Other $ 2    
Effective Income Tax Rate Reconciliation, Percent      
Statutory tax rate difference between Switzerland, Ireland and other foreign jurisdictions and the U.S. (4.20%)    
Pillar Two 0.40%    
Other 0.00%    
Other foreign      
Effective Income Tax Rate Reconciliation, Amount      
Statutory tax rate difference between Switzerland, Ireland and other foreign jurisdictions and the U.S. $ 129    
Effective Income Tax Rate Reconciliation, Percent      
Statutory tax rate difference between Switzerland, Ireland and other foreign jurisdictions and the U.S. 1.40%