v3.25.4
REVENUE - Disaggregation of Revenue by Product and Region (Details) - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Revenue from External Customer [Line Items]      
Total Revenues $ 48,194 $ 48,300 $ 45,006
Performance obligation satisfied in previous period 1,300 797 462
United States      
Revenue from External Customer [Line Items]      
Total Revenues 33,279 34,105 31,210
International      
Revenue from External Customer [Line Items]      
Total Revenues 13,828 13,199 13,097
Other      
Revenue from External Customer [Line Items]      
Total Revenues 1,087 996 699
Growth Portfolio      
Revenue from External Customer [Line Items]      
Total Revenues 26,409 22,563 19,366
Opdivo      
Revenue from External Customer [Line Items]      
Total Revenues 10,049 9,304 9,009
Opdivo Qvantig      
Revenue from External Customer [Line Items]      
Total Revenues 238 0 0
Orencia      
Revenue from External Customer [Line Items]      
Total Revenues 3,705 3,682 3,601
Yervoy      
Revenue from External Customer [Line Items]      
Total Revenues 2,900 2,530 2,238
Reblozyl      
Revenue from External Customer [Line Items]      
Total Revenues 2,327 1,773 1,008
Breyanzi      
Revenue from External Customer [Line Items]      
Total Revenues 1,358 747 364
Opdualag      
Revenue from External Customer [Line Items]      
Total Revenues 1,185 928 627
Camzyos      
Revenue from External Customer [Line Items]      
Total Revenues 1,068 602 231
Zeposia      
Revenue from External Customer [Line Items]      
Total Revenues 577 566 434
Abecma      
Revenue from External Customer [Line Items]      
Total Revenues 427 406 472
Sotyktu      
Revenue from External Customer [Line Items]      
Total Revenues 291 246 170
Krazati      
Revenue from External Customer [Line Items]      
Total Revenues 205 126 0
Cobenfy      
Revenue from External Customer [Line Items]      
Total Revenues 155 10 0
Other Growth products      
Revenue from External Customer [Line Items]      
Total Revenues 1,924 1,643 1,212
Legacy Portfolio      
Revenue from External Customer [Line Items]      
Total Revenues 21,785 25,737 25,640
Eliquis      
Revenue from External Customer [Line Items]      
Total Revenues 14,443 13,333 12,206
Revlimid      
Revenue from External Customer [Line Items]      
Total Revenues 2,951 5,773 6,097
Pomalyst/Imnovid      
Revenue from External Customer [Line Items]      
Total Revenues 2,733 3,545 3,441
Sprycel      
Revenue from External Customer [Line Items]      
Total Revenues 493 1,286 1,930
Abraxane      
Revenue from External Customer [Line Items]      
Total Revenues 368 875 1,004
Other Legacy products      
Revenue from External Customer [Line Items]      
Total Revenues $ 798 $ 925 $ 962