v3.25.4
Segment Reporting and Disaggregation of Relevant Expense Captions - Segment Reporting Information, by Segment (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Segment Reporting Information [Line Items]      
Revenue from Contract with Customer, Excluding Assessed Tax $ 2,860.5 $ 2,355.3 $ 1,887.1
Less:      
Cost of revenues 52.1 34.0 39.7
Total research and development 1,015.7 731.1 565.0
Acquired in-process research and development 17.4 12.5 143.9
Selling, general, and administrative 1,156.2 1,007.2 887.6
Unrealized loss (gain) on equity investments 4.0 37.1 (28.4)
Charges associated with convertible senior notes 0.0 138.4 0.0
Investment income and other, net (90.3) (91.0) (52.8)
Provision for income taxes 226.8 144.7 82.4
Net income 478.6 341.3 249.7
INGREZZA net product sales      
Segment Reporting Information [Line Items]      
Revenue from Contract with Customer, Excluding Assessed Tax 2,510.0 2,310.0 1,840.0
CRENESSITY net product sales      
Segment Reporting Information [Line Items]      
Revenue from Contract with Customer, Excluding Assessed Tax 301.2    
Reportable Segment      
Segment Reporting Information [Line Items]      
Revenue from Contract with Customer, Excluding Assessed Tax 2,860.5 2,355.3 1,887.1
Less:      
Cost of revenues 52.1 34.0 39.7
Total research and development 1,015.7 731.1 565.0
Acquired in-process research and development 17.4 12.5 143.9
Selling, general, and administrative 1,156.2 1,007.2 887.6
Unrealized loss (gain) on equity investments 4.0 37.1 (28.4)
Charges associated with convertible senior notes 0.0 138.4 0.0
Investment income and other, net (90.3) (91.0) (52.8)
Provision for income taxes 226.8 144.7 82.4
Net income 478.6 341.3 249.7
Reportable Segment | INGREZZA net product sales      
Segment Reporting Information [Line Items]      
Revenue from Contract with Customer, Excluding Assessed Tax 2,513.7 2,313.5 1,836.0
Reportable Segment | CRENESSITY net product sales      
Segment Reporting Information [Line Items]      
Revenue from Contract with Customer, Excluding Assessed Tax 301.2 1.7 0.0
Reportable Segment | Other revenues      
Segment Reporting Information [Line Items]      
Revenue from Contract with Customer, Excluding Assessed Tax 45.6 40.1 51.1
Reportable Segment | External research and development      
Less:      
Total research and development 507.3 343.5 310.0
Reportable Segment | Payroll and benefits      
Less:      
Total research and development 306.4 236.7 206.7
Reportable Segment | Milestones      
Less:      
Total research and development 65.4 71.7 0.8
Reportable Segment | Other research and development      
Less:      
Total research and development $ 136.6 $ 79.2 $ 47.5