Income Taxes - Provision for Income Taxes on Earnings Subject to Income Taxes Differs from Statutory Federal Rate (Details) - USD ($) $ in Millions |
12 Months Ended | ||
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Dec. 31, 2025 |
Dec. 31, 2024 |
Dec. 31, 2023 |
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| Income Tax Disclosure [Abstract] | |||
| Federal income taxes at 21% | 21.00% | 21.00% | 21.00% |
| Federal income taxes at 21% | $ 148.1 | $ 102.1 | $ 69.7 |
| State income tax, net of federal benefit | 3.1 | 34.6 | 17.5 |
| Branded prescription drug fee | 7.5 | 8.7 | |
| Loss on extinguishment of convertible senior notes | 29.1 | 0.0 | |
| Stock-based compensation expense | 13.6 | (20.4) | (3.9) |
| Officer compensation | 3.3 | 9.6 | |
| Foreign rate differential | 7.2 | 3.4 | |
| Change in tax rate | (0.6) | (5.5) | |
| Research and development tax credits | (35.6) | (49.2) | (42.2) |
| Change in valuation allowance | 23.9 | 22.0 | |
| Other | 7.2 | 3.1 | |
| Provision for income taxes | $ 226.8 | $ 144.7 | $ 82.4 |
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- Definition Effective Income Tax Rate Reconciliation, Nondeductible Expense, Loss On Extinguishment Of Convertible Senior Notes No definition available.
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- Definition Income tax reconciliation nondeductible expense branded prescription drug fee. No definition available.
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- Definition Income tax reconciliation nondeductible expense officer compensation cost. No definition available.
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- Definition Percentage of domestic federal statutory tax rate applicable to pretax income (loss). Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- References No definition available.
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- Definition Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to increase (decrease) in the valuation allowance for deferred tax assets. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations, attributable to increase (decrease) in the income tax rates. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to foreign income tax expense (benefit). Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition The amount of income tax expense or benefit for the period computed by applying the domestic federal statutory tax rates to pretax income from continuing operations. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount of reported income tax expense (benefit) in excess of (less than) expected income tax expense (benefit) computed by applying domestic federal statutory income tax rate to pretax income (loss) from continuing operation, attributable to nondeductible expense for award under share-based payment arrangement. Includes, but is not limited to, expense determined to be nondeductible upon grant or after for award under share-based payment arrangement. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to other adjustments. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to state and local income tax expense (benefit). Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to research tax credit. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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