v3.25.4
CONSOLIDATED STATEMENTS OF INCOME AND COMPREHENSIVE INCOME - USD ($)
shares in Millions, $ in Millions
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Total revenues $ 2,860.5 $ 2,355.3 $ 1,887.1
Operating expenses:      
Cost of revenues 52.1 34.0 39.7
Research and development 1,015.7 731.1 565.0
Acquired in-process research and development 17.4 12.5 143.9
Selling, general, and administrative 1,156.2 1,007.2 887.6
Total operating expenses 2,241.4 1,784.8 1,636.2
Operating income 619.1 570.5 250.9
Other income (expense):      
Unrealized (loss) gain on equity investments (4.0) (37.1) 28.4
Charges associated with convertible senior notes 0.0 (138.4) 0.0
Investment income and other, net 90.3 91.0 52.8
Total other income (expense), net 86.3 (84.5) 81.2
Income before provision for income taxes 705.4 486.0 332.1
Provision for income taxes 226.8 144.7 82.4
Net income 478.6 341.3 249.7
Foreign currency translation adjustments, net of tax 3.8 (1.1) 2.4
Unrealized gain (loss) on available-for-sale debt securities, net of tax 3.5 (0.1) 12.5
Comprehensive income $ 485.9 $ 340.1 $ 264.6
Earnings per share, basic (in USD per share) $ 4.81 $ 3.40 $ 2.56
Earnings per share, diluted (in USD per share) $ 4.67 $ 3.29 $ 2.47
Weighted average common shares outstanding, basic (in shares) 99.5 100.4 97.7
Weighted average common shares outstanding, diluted (in shares) 102.5 103.7 101.0
Net product sales      
Total revenues $ 2,833.9 $ 2,330.6 $ 1,860.6
Collaboration revenues      
Total revenues $ 26.6 $ 24.7 $ 26.5