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Agreements with Ligand Pharmaceuticals Incorporated - Additional Information (Detail) - USD ($)	1 Months Ended	12 Months Ended
	May 31, 2014	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
License agreement entered date		2014-05
Common stock issued value as part of partial consideration of agreement		$ 73,948,000	$ 643,797,000	$ 271,882,000
Ligand [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
One time nonrefundable mile stone payments maximum payable amount		1,540,000,000
Legal costs		$ 0
Sale and transfer of price equals to percentage of cost of goods		125.00%
Ligand [Member] \| Management Rights Letter [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Date agreement might terminate	Mar. 28, 2023
Ligand [Member] \| Minimum [Member] \| Management Rights Letter [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Percentage of voting interest beneficiary owned	7.50%
IPO [Member] \| Ligand [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Common stock issued as part of partial consideration of agreement		3,655,964
Common stock issued value as part of partial consideration of agreement		$ 29,200,000