v3.25.3
Leases - Additional Information (Detail)
3 Months Ended 9 Months Ended
Nov. 04, 2025
Lease
Sep. 30, 2025
USD ($)
Sep. 30, 2024
USD ($)
Sep. 30, 2025
USD ($)
Sep. 30, 2024
USD ($)
Dec. 31, 2024
Lessee Lease Description [Line Items]            
Number of operating leases | Lease 3          
Lessee, operating lease, expiration period We currently have three operating leases for administrative and research and development office and lab space in San Diego, California and Boston, Massachusetts that expire between November 2025 and May 2033.          
Lease agreement additional extended lease term   5 years   5 years    
Weighted-average discount rate   12.30%   12.30%   11.40%
Weighted-average remaining lease term   6 years 4 months 24 days   6 years 4 months 24 days   5 years 10 months 24 days
Total cash paid for amounts included in the measurement of lease liabilities   $ 500,000 $ 300,000 $ 1,400,000 $ 1,300,000  
ROU assets obtained in exchange for operating lease liabilities       2,700,000 0  
ASC 842            
Lessee Lease Description [Line Items]            
Total operating lease rent expense   800,000 $ 500,000 2,400,000 $ 1,500,000  
San Diego Corporate Headquarters Lease            
Lessee Lease Description [Line Items]            
Reimbursements for tenant improvements and rent credits       1,300,000    
Boston Lease            
Lessee Lease Description [Line Items]            
Reimbursements for tenant improvements and rent credits       1,400,000    
2025 San Diego Corporate Headquarters Lease            
Lessee Lease Description [Line Items]            
Rent credit to be applied as credit, in equal monthly installments       2,400,000    
Lease allowance   $ 6,200,000   $ 6,200,000