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Amount of cost to be recognized for option under share-based payment arrangement.

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The number of grants made during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Number of additional shares authorized for issuance under share-based payment arrangement.

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Number of shares authorized for issuance under share-based payment arrangement.

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The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable.

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Amount of accumulated difference between fair value of underlying shares on dates of exercise and exercise price on options exercised (or share units converted) into shares.

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The weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology.

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Maximum number of shares that may be issued in accordance with the plan as a proportion of outstanding capital stock.

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Equity-Based Compensation - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024	Mar. 31, 2025	Aug. 20, 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	$ 15,802	$ 14,904	$ 45,451	$ 41,213
Research and Development Expense
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	8,360	7,604	23,943	20,944
General and Administrative
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	7,442	7,300	21,508	20,269
Employee Stock Option
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Intrinsic value of stock options exercised	$ 8,600	$ 10,400	$ 16,000	$ 19,000
Weighted-average fair value of options granted	$ 33.67	$ 29.36	$ 22.73	$ 26.03
Unrecognized stock-based compensation expense	$ 73,500		$ 73,500
Unrecognized compensation cost, recognition period			2 years 1 month 6 days
Equity-based compensation expense	12,545	$ 12,382	$ 36,506	$ 34,985
Employee Stock Option \| Research and Development Expense
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	5,919	5,950	17,615	16,925
Employee Stock Option \| General and Administrative
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	6,626	$ 6,432	18,891	$ 18,060
Restricted Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Unrecognized stock-based compensation expense	$ 31,300		$ 31,300
Unrecognized compensation cost, recognition period			2 years 9 months 18 days
Granted	243,950	152,288	763,050	396,272
Equity-based compensation expense	$ 2,800	$ 2,300	$ 8,000	$ 5,600
Restricted Stock \| Research and Development Expense
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	2,300	1,500	5,800	3,600
Restricted Stock \| General and Administrative
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	$ 500	$ 800	$ 2,200	$ 2,000
2020 Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares authorized for issuance under plan						4,457,370
Maximum number of shares to be issued, percentage			4.00%
Shares remaining available for future grants	4,138,724		4,138,724
Performance stock options vesting					40.00%
Second clinical milestone vesting percentage					40.00%
Third clinical milestone vesting percentage					20.00%
Granted			88,000
Option Indexed to Issuer's Equity, Strike Price			$ 30.17
Performance stock options outstanding	88,000		88,000
2020 Plan \| Restricted Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Granted	0	0	285,723	0
2020 Plan \| Performance Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options vesting					40.00%
Second clinical milestone vesting percentage					40.00%
Third clinical milestone vesting percentage					20.00%
Option Indexed to Issuer's Equity, Strike Price			$ 30.17
2020 Plan \| Minimum [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range					0.00%
2020 Plan \| Minimum [Member] \| Performance Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range					0.00%
2020 Plan \| Maximum [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range					100.00%
2020 Plan \| Maximum [Member] \| Performance Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range					100.00%
2020 ESPP
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares authorized for issuance under plan						445,653
Shares remaining available for future grants	2,318,998		2,318,998
Share-based compensation, description			The 2020 ESPP initially reserved and authorized the issuance of up to a total of 445,653 shares of common stock to participating employees. The 2020 ESPP provides that the number of shares reserved and available for issuance will automatically increase on January 1, 2021 and each January 1 thereafter through January 1, 2030, by the lesser of (i) 438,898 shares of common stock, (ii) 1% of the Company’s outstanding number of shares of common stock on the immediately preceding December 31 or (iii) such lesser number of shares of common stock as determined by the administrator of the 2020 ESPP
2020 ESPP \| Lesser of Potential Outcome 1
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Maximum number of shares to be issued, percentage			1.00%
Number of additional shares authorized			438,898
2018 Plan \| Restricted Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Granted			1,048,773