Nature of Business, Basis of Presentation and Segment Information - Schedule of Revenue and Expense Categories in Single Operating Segment (Detail) - USD ($) $ in Thousands |
3 Months Ended | 9 Months Ended | ||
|---|---|---|---|---|
Sep. 30, 2025 |
Sep. 30, 2024 |
Sep. 30, 2025 |
Sep. 30, 2024 |
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| Segment Reporting Information [Line Items] | ||||
| Revenue from external customers | $ 44,044 | $ 38,783 | $ 111,988 | $ 114,695 |
| Research and development expenses | (30,544) | (36,134) | (97,950) | (109,930) |
| Other segment (expenses) income | (17,873) | (5,761) | (20,868) | 42,686 |
| Net loss | (33,127) | (32,072) | (93,841) | (45,642) |
| Product [Member] | ||||
| Segment Reporting Information [Line Items] | ||||
| Revenue from external customers | 32,032 | 29,516 | 82,767 | 83,554 |
| Cost of sales | 2,113 | 1,300 | 4,465 | 4,676 |
| Operating Segments [Member] | ||||
| Segment Reporting Information [Line Items] | ||||
| Revenue from external customers | 44,044 | 38,783 | 111,988 | 114,695 |
| Research and development expenses | (30,743) | (36,395) | (99,942) | (110,722) |
| Commercial expenses | (11,112) | (12,440) | (35,776) | (38,606) |
| General and administrative expenses | (12,524) | (10,810) | (34,634) | (34,468) |
| Other segment (expenses) income | (20,710) | (9,971) | (31,125) | 27,958 |
| Net loss | (33,127) | (32,072) | (93,841) | (45,642) |
| Operating Segments [Member] | Product [Member] | ||||
| Segment Reporting Information [Line Items] | ||||
| Cost of sales | $ (2,082) | $ (1,239) | $ (4,352) | $ (4,499) |
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- Definition Commercial segment operating expense. No definition available.
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- Definition The aggregate costs related to goods produced and sold and services rendered by an entity during the reporting period. This excludes costs incurred during the reporting period related to financial services rendered and other revenue generating activities. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition The aggregate amount of income or expense from ancillary business-related activities (that is to say, excluding major activities considered part of the normal operations of the business). Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount of expense for research and development. Includes, but is not limited to, cost for computer software product to be sold, leased, or otherwise marketed and writeoff of research and development assets acquired in transaction other than business combination or joint venture formation or both. Excludes write-down of intangible asset acquired in business combination or from joint venture formation or both, used in research and development activity. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. No definition available.
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