Exhibit 3.1.

INSTRUCTIONS: 1. Enter the current name as on file with the Nevada Secretary of State and enter the Entity or Nevada Business Identif ication Number (NVID). 2. Indicate the current number of authorized shares and par value, if any, and each class or series before the change. 3. Indicate the number of authorized shares and par value, if any of each class or series af ter the change. 4. Indicate the change of the affected class or series of issued, if any, shares after the change in exchange for each issued share of the same class or series. 5. Indicate provisions, if any, regarding f ractional shares that are af f ected by the change. 6. NRS required statement. 7. This section is optional. If an effective date and time is indicated the date must not be more than 90 days af ter the date on which the certif icate is f iled. 8. Must be signed by an Officer. Form will be returned if unsigned. Name of entity as on f ile with the Nevada Secretary of State: Aethlon Medical, Inc. 1. Entity Information: D): C3159 - 1991 Entity or Nevada Business Identif ication Number (NVI The current number of authorized shares and the par value, if any, of each class or series, if any, of shares bef ore the change: 60,000,000 shares of common stock, par value $0.001. 2. Current Authorized Shares: The number of authorized shares and the par value, if any, of each class or series, if any, of shares af ter the change: 6,000,000 shares of common stock, par value $0.001. 3. Authorized Shares After Change: The number of shares of each affected class or series, if any, to be issued after the change in exchange for each issued share of the same class or series: 1 share of Common Stock will be issued in exchange for 10 shares of issued and outstanding Common Stock, effective after processing by Nasdaq. 4. Issuance: The provisions, if any, for the issuance of fractional shar es, or for the p ayment of money or the issuance of scrip to stockholders otherwise entitled to a fr action of a share and the percentage of outstanding shares affected thereby : No fractional shares. If reverse split would result in issuance of any fractional shares, the company will issue one whole share on a holder - by - holder basis. 5. Provisions: The required approval of the stockholders has been obtained. 6. Provisions: Date: October 16, 2025 Time: 10:00am ET (must not be later than 90 days after the certificate is filed) 7. Effective date and time: (Optional) X CEO 10/08/2025 Signature of Officer Title Date 8. Signature: (Required) FRANCISCO V. AGUILAR Secretary of State 401 North Carson Street Carson City, Nevada 89701 - 4201 (775) 684 - 5708 Website: www.nvsos.gov TYPE OR PRINT - USE DARK INK ONLY - DO NOT HIGHLIGHT Certificate of Change Pursuant to NRS 78.209 This form must be accompanied by appropriate fees. If necessary, additional pag es may be attached to this form. Page 1 of 1 Revised: 8/1/2023