Schedule of Investments - Virtus LifeSci Biotech Clinical Trials ETF

July 31, 2025 (unaudited)

 

Security Description  Shares   Value 
COMMON STOCKS - 98.9%          
Health Care - 98.9%          
89bio, Inc.*   12,649   $120,165 
AbCellera Biologics, Inc. (Canada)*(1)   38,628    172,667 
Akero Therapeutics, Inc.*   2,272    110,987 
Allogene Therapeutics, Inc.*(1)   86,914    106,905 
Altimmune, Inc.*(1)   17,018    62,796 
AnaptysBio, Inc.*   5,198    127,611 
Annexon, Inc.*   44,900    107,760 
Apogee Therapeutics, Inc.*   2,907    111,222 
Arbutus Biopharma Corp.*(1)   33,989    111,484 
Arcellx, Inc.*   1,829    130,572 
Arcturus Therapeutics Holdings, Inc.*   9,627    117,546 
Arcus Biosciences, Inc.*   13,014    118,818 
Arcutis Biotherapeutics, Inc.*   9,013    131,410 
ArriVent Biopharma, Inc.*(1)   5,149    100,457 
Arrowhead Pharmaceuticals, Inc.*   7,502    118,532 
Arvinas, Inc.*   16,074    119,591 
Astria Therapeutics, Inc.*   21,728    150,358 
Autolus Therapeutics PLC (United Kingdom)*(2)   56,595    135,828 
Avidity Biosciences, Inc.*   3,786    138,984 
Beam Therapeutics, Inc.*   6,977    137,517 
Belite Bio, Inc.*(1)(2)   1,958    127,290 
Bicara Therapeutics, Inc.*(1)   10,517    116,844 
Bicycle Therapeutics PLC (United Kingdom)*(2)   14,002    119,297 
Biohaven Ltd.*   7,805    117,856 
Capricor Therapeutics, Inc.*(1)   8,729    71,403 
Cartesian Therapeutics, Inc.*(1)   11,883    152,221 
Celcuity, Inc.*(1)   9,688    379,431 
Celldex Therapeutics, Inc.*   5,979    131,418 
Centessa Pharmaceuticals PLC*(2)   10,106    173,520 
CG oncology, Inc.*   4,592    122,560 
Cogent Biosciences, Inc.*   16,853    192,461 
Compass Pathways PLC (United Kingdom)*(2)   26,920    117,102 
Corvus Pharmaceuticals, Inc.*(1)   28,698    119,671 
Crinetics Pharmaceuticals, Inc.*   3,782    108,127 
Cullinan Therapeutics, Inc.*   13,595    105,633 
CureVac NV (Germany)*   21,728    117,114 
Cytokinetics, Inc.*   3,665    137,951 
Denali Therapeutics, Inc.*   8,153    112,756 
Dianthus Therapeutics, Inc.*   6,308    130,386 
Disc Medicine, Inc.*   2,308    137,926 
Dyne Therapeutics, Inc.*   8,415    82,888 
Edgewise Therapeutics, Inc.*   7,891    112,526 
Enliven Therapeutics, Inc.*(1)   6,189    116,415 
Entrada Therapeutics, Inc.*   15,501    91,146 
Erasca, Inc.*   79,529    112,534 
EyePoint Pharmaceuticals, Inc.*   13,734    134,868 
GH Research PLC (Ireland)*   9,484    136,190 
Ideaya Biosciences, Inc.*   5,461    132,975 
Immatics NV (Germany)*   19,817    127,820 
Immunome, Inc.*   12,429    130,753 
Immunovant, Inc.*(1)   7,634    122,755 
Intellia Therapeutics, Inc.*   14,572    169,618 
iTeos Therapeutics, Inc.*   12,192    123,627 
Janux Therapeutics, Inc.*   4,761    114,335 
KalVista Pharmaceuticals, Inc.*   9,296    126,704 
Keros Therapeutics, Inc.*   8,921    127,749 
Kura Oncology, Inc.*   18,270    110,533 
Kymera Therapeutics, Inc.*(1)   2,573    112,569 
Security Description  Shares   Value 
COMMON STOCKS (continued)          
Health Care (continued)          
LENZ Therapeutics, Inc.*(1)   4,114   $122,474 
Liquidia Corp.*   8,421    157,388 
Maze Therapeutics, Inc.*(1)   8,980    132,455 
MBX Biosciences, Inc.*(1)   11,351    150,401 
Mereo Biopharma Group PLC (United Kingdom)*(2)   43,769    73,970 
Merus NV (Netherlands)*   2,197    145,529 
Metsera, Inc.*(1)   3,519    116,092 
Mind Medicine MindMed, Inc.*   16,668    151,512 
Mineralys Therapeutics, Inc.*   8,155    115,393 
Monte Rosa Therapeutics, Inc.*   24,732    122,423 
MoonLake Immunotherapeutics*   2,764    139,416 
Neurogene, Inc.*(1)   5,965    129,858 
Newamsterdam Pharma Co. NV (Netherlands)*   5,786    126,193 
Nurix Therapeutics, Inc.*   10,174    114,559 
Nuvalent, Inc. Class A*(1)   1,562    122,383 
Nuvation Bio, Inc.*(1)   67,226    158,653 
Olema Pharmaceuticals, Inc.*(1)   29,970    154,046 
ORIC Pharmaceuticals, Inc.*   12,583    125,453 
Pharvaris NV (Netherlands)*   7,062    140,393 
Praxis Precision Medicines, Inc.*   2,702    146,502 
Protagonist Therapeutics, Inc.*   2,160    116,338 
Prothena Corp. PLC (Ireland)*   24,000    164,880 
Rapport Therapeutics, Inc.*   10,923    156,854 
Recursion Pharmaceuticals, Inc.
Class A*(1)
   23,536    140,039 
REGENXBIO, Inc.*   11,929    101,516 
Relay Therapeutics, Inc.*   35,269    124,147 
Replimune Group, Inc.*(1)   12,309    86,532 
Revolution Medicines, Inc.*   2,960    110,319 
Rocket Pharmaceuticals, Inc.*   39,635    120,887 
Sana Biotechnology, Inc.*(1)   47,905    194,494 
Savara, Inc.*   53,840    139,446 
Scholar Rock Holding Corp.*   3,652    135,307 
Silence Therapeutics PLC (United Kingdom)*(1)(2)   21,787    134,208 
Sionna Therapeutics, Inc.*(1)   7,162    120,035 
Soleno Therapeutics, Inc.*   1,517    131,175 
Spyre Therapeutics, Inc.*   6,871    116,601 
Stoke Therapeutics, Inc.*   10,294    132,278 
Structure Therapeutics, Inc.*(2)   5,476    97,473 
Summit Therapeutics, Inc.*(1)   6,036    159,169 
Syndax Pharmaceuticals, Inc.*   11,404    113,128 
Tango Therapeutics, Inc.*(1)   24,095    145,534 
Taysha Gene Therapies, Inc.*(1)   45,917    125,353 
Tectonic Therapeutic, Inc.*   5,422    120,314 
Terns Pharmaceuticals, Inc.*   30,962    180,508 
Tourmaline Bio, Inc.*   6,115    135,325 
Tyra Biosciences, Inc.*(1)   11,779    128,744 
uniQure NV (Netherlands)*   7,610    105,931 
Upstream Bio, Inc.*(1)   10,526    161,153 
Vaxcyte, Inc.*   3,531    119,877 
Vera Therapeutics, Inc.*   5,403    112,328 
Viking Therapeutics, Inc.*(1)   4,257    138,650 
Vir Biotechnology, Inc.*   23,310    118,182 
Viridian Therapeutics, Inc.*   7,765    136,043 
WaVe Life Sciences Ltd.*   16,900    136,890 
Xencor, Inc.*   12,903    107,353 
Xenon Pharmaceuticals, Inc. (Canada)*   3,710    113,303 
Xeris Biopharma Holdings, Inc.*   27,529    140,123 
Zymeworks, Inc.*   9,288    116,657 

 

 

Schedule of Investments - Virtus LifeSci Biotech Clinical Trials ETF (continued)

July 31, 2025 (unaudited)

 

Security Description  Shares   Value 
COMMON STOCKS (continued)        
Health Care (continued)        
Total Health Care       $14,990,369 
Total Common Stocks          
(Cost $17,113,973)        14,990,369 
SECURITIES LENDING COLLATERAL - 15.4%          
Money Market Fund - 15.4%          
Dreyfus Government Cash Management Fund, Institutional Shares, 4.20%(3)(4)          
(Cost $2,328,672)   2,328,672    2,328,672 
           
TOTAL INVESTMENTS - 114.3%          
(Cost $19,442,645)        17,319,041 
Liabilities in Excess of Other Assets - (14.3)%        (2,173,226)
Net Assets - 100.0%       $15,145,815 

 

* Non-income producing security.
(1) All or a portion of the security was on loan. The aggregate market value of securities on loan was $3,169,235; total market value of collateral held by the Fund was $3,350,620. Market value of the collateral held includes non-cash U.S. Treasury securities having a value of $1,021,948.
(2) American Depositary Receipts.
(3) Represents securities purchased with cash collateral received for securities on loan.
(4) The rate shown reflects the seven-day yield as of July 31, 2025.

 


 

 

Schedule of Investments - Virtus LifeSci Biotech Clinical Trials ETF (continued)

July 31, 2025 (unaudited)

 

Fair Value Measurements

The Fund utilizes a fair value hierarchy which prioritizes the inputs to valuation techniques used to measure fair value into three broad levels. Level 1 includes unadjusted quoted prices in active markets for identical assets or liabilities that the Fund has the ability to access. Level 2 includes observable inputs other than quoted prices included in Level 1 that are observable for the asset or liability, either directly or indirectly. These inputs may include quoted prices for the identical instrument on an inactive market, prices for similar securities, interest rates, prepayment speeds, credit risk, yield curves, default rates and similar data. Level 3 includes unobservable inputs for the asset or liability, to the extent relevant observable inputs are not available; representing the Fund’s own assumptions about the assumptions a market participant would use in valuing the asset or liability, and would be based on the best information available. The inputs or methodology used for valuing securities are not necessarily an indication of the risk associated with investing in those securities.

 

The following table summarizes valuation of the Fund’s investments under the fair value hierarchy levels as of July 31, 2025.

 

   Level 1   Level 2   Level 3   Total 
Asset Valuation Inputs                    
Common Stocks  $14,990,369   $   $   $14,990,369 
Money Market Fund   2,328,672            2,328,672 
Total  $17,319,041   $   $   $17,319,041