v3.25.2
General Information - Additional Information (Detail) - Subsidiary
6 Months Ended
Aug. 11, 2025
Apr. 16, 2025
Jun. 30, 2025
Disclosure Of General Information About Financial Statements [Abstract]      
Description of nature of entity's operations     clinical-stage biopharmaceutical company developing a portfolio of new medicines to treat patients with cancer
Name of reporting entity     NuCana plc
Domicile of entity     United Kingdom
Country of incorporation     England and Wales
Number of subsidiaries     3
Name of subsidiary     NuCana, Inc., NuCana Limited and NuCana BioMed Trustee Company Limited
Description of change In ratio of shares one ADS representing 25 ordinary shares, to one ADS representing 5,000 ordinary shares. from one ADS representing one ordinary share, to one ADS representing 25 ordinary shares.