v3.25.2
Cover - shares
 6 Months Ended
Jun. 30, 2025
Aug. 15, 2025
Document Information [Line Items]    
Document Type 10-Q  
Document Quarterly Report true  
Document Transition Report false  
Entity Interactive Data Current Yes  
Amendment Flag false  
Document Period End Date Jun. 30, 2025  
Document Fiscal Year Focus 2025  
Document Fiscal Period Focus Q2  
Entity Information [Line Items]    
Entity Registrant Name KLOTHO NEUROSCIENCES, INC.  
Entity Central Index Key 0001907223  
Entity File Number 001-41340  
Entity Tax Identification Number 86-2727441  
Entity Incorporation, State or Country Code DE  
Current Fiscal Year End Date --12-31  
Entity Current Reporting Status Yes  
Entity Shell Company false  
Entity Filer Category Non-accelerated Filer  
Entity Small Business true  
Entity Emerging Growth Company true  
Entity Ex Transition Period false  
Entity Contact Personnel [Line Items]    
Entity Address, Address Line One 1300 South Boulevard  
Entity Address, Address Line Two Unit D  
Entity Address, City or Town Charlotte  
Entity Address, State or Province NC  
Entity Address, Postal Zip Code 28203  
Entity Phone Fax Numbers [Line Items]    
City Area Code (833)  
Local Phone Number 931-6330  
Entity Listings [Line Items]    
Entity Common Stock, Shares Outstanding   61,374,435
Common Stock    
Entity Listings [Line Items]    
Title of 12(b) Security Common Stock  
Trading Symbol KLTO  
Security Exchange Name NASDAQ  
Warrants    
Entity Listings [Line Items]    
Title of 12(b) Security Warrants  
Trading Symbol KLTOW  
Security Exchange Name NASDAQ