The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIVAX SA SPONSORED ADS 00370M103 956,250 125,000 SH SOLE 125,000 0 0
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 116,500 10,000 SH SOLE 10,000 0 0
ADMA BIOLOGICS INC COM 000899104 3,186,750 175,000 SH SOLE 175,000 0 0
ADVERUM BIOTECHNOLOGIES INC COM NEW 00773U207 617,579 287,246 SH SOLE 287,246 0 0
AKERO THERAPEUTICS INC COM 00973Y108 3,841,920 72,000 SH SOLE 72,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 34,810,108 106,750 SH SOLE 106,750 0 0
ANAPTYSBIO INC COM 032724106 7,127,088 321,040 SH SOLE 321,040 0 0
ANI PHARMACEUTICALS INC COM 00182C103 3,310,981 50,743 SH SOLE 50,743 0 0
ARCELLX INC COMMON STOCK 03940C100 8,101,591 123,031 SH SOLE 123,031 0 0
ARGENX SE SPONSORED ADR 04016X101 23,634,109 42,876 SH SOLE 42,876 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 14,671,000 85,000 SH SOLE 85,000 0 0
AXOGEN INC COM 05463X106 15,834,436 1,459,395 SH SOLE 1,459,395 0 0
AXSOME THERAPEUTICS INC COM 05464T104 208,780 2,000 SH SOLE 2,000 0 0
BETA BIONICS INC COM 08659B102 55,621,500 3,820,158 SH SOLE 3,820,158 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 695,000 100,000 SH SOLE 100,000 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 49,599,651 902,304 SH SOLE 902,304 0 0
C4 THERAPEUTICS INC COM STK 12529R107 9,979,887 6,978,942 SH SOLE 6,978,942 0 0
CALCIMEDICA INC COM NEW 38942Q202 1,254,246 783,904 SH SOLE 783,904 0 0
CELCUITY INC COM 15102K100 40,207,770 3,011,818 SH SOLE 3,011,818 0 0
CERIBELL INC COM 15678C102 936,500 50,000 SH SOLE 50,000 0 0
CG ONCOLOGY INC COM 156944100 4,030,000 155,000 SH SOLE 155,000 0 0
CIDARA THERAPEUTICS INC COM NEW 171757206 22,543,524 462,811 SH SOLE 462,811 0 0
CRESCENT BIOPHARMA INC. COM G2545C104 6,456,000 400,000 SH SOLE 400,000 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 2,960,761 1,304,300 SH SOLE 1,304,300 0 0
DELCATH SYS INC COM NEW 24661P807 340,000 25,000 SH SOLE 25,000 0 0
DENALI THERAPEUTICS INC COM 24823R105 2,547,719 182,110 SH SOLE 182,110 0 0
EDAP TMS S A SPONSORED ADR 268311107 12,060,269 7,309,254 SH SOLE 7,309,254 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105 1,002,823 76,493 SH SOLE 76,493 0 0
ELEVANCE HEALTH INC COM 036752103 27,227,200 70,000 SH SOLE 70,000 0 0
ENOVIS CORPORATION COM 194014502 9,878,400 315,000 SH SOLE 315,000 0 0
ERASCA INC COM 29479A108 2,745,946 2,162,162 SH SOLE 2,162,162 0 0
ESSA PHARMA INC COM NEW 29668H708 3,845,444 2,262,026 SH SOLE 2,262,026 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108 9,050,249 211,900 SH SOLE 211,900 0 0
ETON PHARMACEUTICALS INC COM 29772L108 4,061,250 285,000 SH SOLE 285,000 0 0
EVOLUS INC COM 30052C107 19,515,990 2,119,000 SH SOLE 2,119,000 0 0
GENEDX HOLDINGS CORP COM CL A 81663L200 3,692,400 40,000 SH SOLE 40,000 0 0
GERON CORP COM 374163103 22,757,400 16,140,000 SH SOLE 16,140,000 0 0
GRIFOLS S A SP ADR REP B NVT 398438408 52,041,517 5,756,805 SH SOLE 5,756,805 0 0
HUMANA INC COM 444859102 19,460,608 79,600 SH SOLE 79,600 0 0
IDEAYA BIOSCIENCES INC COM 45166A102 5,255,000 250,000 SH SOLE 250,000 0 0
IMMUNIC INC COM 4525EP101 5,086,872 7,293,007 SH SOLE 7,293,007 0 0
INHIBIKASE THERAPEUTICS INC COM NEW 45719W205 12,333,750 6,325,000 SH SOLE 6,325,000 0 0
INSMED INC COM PAR $.01 457669307 7,323,774 72,772 SH SOLE 72,772 0 0
INSPIRE MED SYS INC COM 457730109 14,144,930 109,000 SH SOLE 109,000 0 0
INSPIREMD INC COM 45779A846 4,281,690 1,886,207 SH SOLE 1,886,207 0 0
INTEGRA LIFESCIENCES HLDGS C COM NEW 457985208 17,028,527 1,387,818 SH SOLE 1,387,818 0 0
IO BIOTECH INC COM 449778109 267,811 192,670 SH SOLE 192,670 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 5,610,136 3,261,707 SH SOLE 3,261,707 0 0
JADE BIOSCIENCES INC COM NEW 008064206 7,959,473 796,744 SH SOLE 796,744 0 0
JASPER THERAPEUTICS INC COM NEW 471871202 8,294,031 1,494,420 SH SOLE 1,494,420 0 0
KINIKSA PHARMACEUTICALS INTL ORD SHS CL A G52694109 7,047,245 254,689 SH SOLE 254,689 0 0
KRYSTAL BIOTECH INC COM 501147102 126,869,807 922,958 SH SOLE 922,958 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 2,421,120 8,000 SH SOLE 8,000 0 0
MEREO BIOPHARMA GROUP PLC SPON ADS 589492107 1,625,217 599,711 SH SOLE 599,711 0 0
MERUS N V COM N5749R100 2,104,000 40,000 SH SOLE 40,000 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 15,200,639 298,696 SH SOLE 298,696 0 0
MURAL ONCOLOGY PUB LTD CO ORD SHS G63365103 3,269,976 1,323,877 SH SOLE 1,323,877 0 0
MYOMO INC COM NEW 62857J201 1,521,234 704,275 SH SOLE 704,275 0 0
NEUROPACE INC COM 641288105 25,766,341 2,312,957 SH SOLE 2,312,957 0 0
NOVOCURE LTD ORD SHS G6674U108 122,896,576 6,904,302 SH SOLE 6,904,302 0 0
NURIX THERAPEUTICS INC COM 67080M103 27,596,068 2,422,833 SH SOLE 2,422,833 0 0
NUVALENT INC COM 670703107 9,537,500 125,000 SH SOLE 125,000 0 0
ORGANOGENESIS HLDGS INC COM 68621F102 45,176,665 12,343,351 SH SOLE 12,343,351 0 0
ORTHOFIX MED INC COM 68752M108 2,911,789 261,147 SH SOLE 261,147 0 0
ORTHOPEDIATRICS CORP COM 68752L100 966,600 45,000 SH SOLE 45,000 0 0
PHARVARIS N V COM N69605108 12,900,237 732,968 SH SOLE 732,968 0 0
PRAXIS PRECISION MEDICINES I COM NEW 74006W207 40,651,417 966,740 SH SOLE 966,740 0 0
QUIDELORTHO CORP COM 219798105 5,014,680 174,000 SH SOLE 174,000 0 0
REVOLUTION MEDICINES INC COM 76155X100 367,900 10,000 SH SOLE 10,000 0 0
RIGEL PHARMACEUTICALS INC COM 766559702 12,327,056 658,145 SH SOLE 658,145 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 4,427,500 125,000 SH SOLE 125,000 0 0
SEPTERNA INC COM 81734D104 797,570 75,456 SH SOLE 75,456 0 0
SIONNA THERAPEUTICS INC COM 829401108 6,523,600 376,000 SH SOLE 376,000 0 0
SOLENO THERAPEUTICS INC COM 834203309 837,800 10,000 SH SOLE 10,000 0 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 62,197,500 750,000 SH Put SOLE 750,000 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 50,083,820 2,984,733 SH SOLE 2,984,733 0 0
SURMODICS INC COM 868873100 23,442,973 789,060 SH SOLE 789,060 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 10,227,610 1,092,110 SH SOLE 1,092,110 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 3,728,000 200,000 SH SOLE 200,000 0 0
TANGO THERAPEUTICS INC COM 87583X109 3,737,600 730,000 SH SOLE 730,000 0 0
TECTONIC THERAPEUTIC INC COM 878972108 1,526,831 76,841 SH SOLE 76,841 0 0
TERNS PHARMACEUTICALS INC COM 880881107 30,463,283 8,167,100 SH SOLE 8,167,100 0 0
TG THERAPEUTICS INC COM 88322Q108 80,759,221 2,243,935 SH SOLE 2,243,935 0 0
THE BEAUTY HEALTH COMPANY COM CL A 88331L108 1,910,000 1,000,000 SH SOLE 1,000,000 0 0
THERATECHNOLOGIES INC COM NEW 88338H704 11,331,247 4,801,376 SH SOLE 4,801,376 0 0
TREVI THERAPEUTICS INC COM 89532M101 3,829,000 700,000 SH SOLE 700,000 0 0
TWIST BIOSCIENCE CORP COM 90184D100 13,038,413 354,401 SH SOLE 354,401 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 60,284,306 209,794 SH SOLE 209,794 0 0
UNITEDHEALTH GROUP INC COM 91324P102 26,907,413 86,250 SH SOLE 86,250 0 0
UROGEN PHARMA LTD COM M96088105 29,934,500 2,185,000 SH SOLE 2,185,000 0 0
VERACYTE INC COM 92337F107 19,338,316 715,439 SH SOLE 715,439 0 0
VERASTEM INC COM NEW 92337C203 3,884,022 935,909 SH SOLE 935,909 0 0
VERICEL CORP COM 92346J108 2,168,050 50,953 SH SOLE 50,953 0 0
XENON PHARMACEUTICALS INC COM 98420N105 2,466,440 78,800 SH SOLE 78,800 0 0
Y-MABS THERAPEUTICS INC COM 984241109 1,578,419 349,982 SH SOLE 349,982 0 0