The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Agilent Technologies Inc Common Stock 00846U101 350,490 2,970 SH SOLE 2,970 0 0
Applied Optoelectronics Inc Common Stock 03823U102 2,938,936 114,400 SH SOLE 114,400 0 0
Apple Inc Common Stock 037833100 110,363,405 537,912 SH DFND 537,912 0 0
AbbVie Inc Common Stock 00287Y109 4,713,263 25,392 SH SOLE 25,392 0 0
Airbnb Inc Common Stock 009066101 1,480,620 11,188 SH DFND 11,188 0 0
Abbott Laboratories Common Stock 002824100 2,716,528 19,973 SH SOLE 19,973 0 0
ACADIA Pharmaceuticals Inc Common Stock 004225108 302,735 14,035 SH SOLE 14,035 0 0
Arcellx Inc Common Stock 03940C100 414,394 6,293 SH SOLE 6,293 0 0
Accenture PLC Common Stock G1151C101 4,941,548 16,533 SH SOLE 16,533 0 0
Adobe Inc Common Stock 00724F101 8,216,558 21,238 SH DFND 21,238 0 0
Analog Devices Inc Common Stock 032654105 4,964,621 20,858 SH DFND 20,858 0 0
ADMA Biologics Inc Common Stock 000899104 540,527 29,683 SH SOLE 29,683 0 0
Automatic Data Processing Inc Common Stock 053015103 3,256,087 10,558 SH DFND 10,558 0 0
Autodesk Inc Common Stock 052769106 2,781,486 8,985 SH DFND 8,985 0 0
American Electric Power Co Inc Common Stock 025537101 1,436,349 13,843 SH DFND 13,843 0 0
Arthur J Gallagher & Co Common Stock 363576109 209,358 654 SH SOLE 654 0 0
Akebia Therapeutics Inc Common Stock 00972D105 102,914 28,273 SH SOLE 28,273 0 0
Akero Therapeutics Inc Common Stock 00973Y108 554,677 10,395 SH SOLE 10,395 0 0
Align Technology Inc Common Stock 016255101 300,656 1,588 SH SOLE 1,588 0 0
Alkermes PLC Common Stock G01767105 515,066 18,003 SH SOLE 18,003 0 0
Alnylam Pharmaceuticals Inc Common Stock 02043Q107 1,171,967 3,594 SH SOLE 3,594 0 0
Altimmune Inc Common Stock 02155H200 43,952 11,357 SH SOLE 11,357 0 0
Applied Materials Inc Common Stock 038222105 6,203,144 33,884 SH DFND 33,884 0 0
Advanced Micro Devices Inc Common Stock 007903107 17,846,479 125,768 SH DFND 125,768 0 0
Amgen Inc Common Stock 031162100 5,184,651 18,569 SH DFND 18,569 0 0
American Tower Corp REIT 03027X100 260,141 1,177 SH SOLE 1,177 0 0
Amazon.com Inc Common Stock 023135106 49,111,768 223,856 SH DFND 223,856 0 0
Arista Networks Inc Common Stock 040413205 1,951,870 19,078 SH SOLE 19,078 0 0
ANSYS Inc Common Stock 03662Q105 1,302,675 3,709 SH DFND 3,709 0 0
Apogee Therapeutics Inc Common Stock 03770N101 204,121 4,700 SH SOLE 4,700 0 0
Amphenol Corp Common Stock 032095101 7,416,718 75,106 SH SOLE 75,106 0 0
Apellis Pharmaceuticals Inc Common Stock 03753U106 277,947 16,057 SH SOLE 16,057 0 0
AppLovin Corp Common Stock 03831W108 3,629,629 10,368 SH DFND 10,368 0 0
Ardelyx Inc Common Stock 039697107 156,890 40,023 SH SOLE 40,023 0 0
ARM Holdings PLC ADR 042068205 2,161,978 13,367 SH DFND 13,367 0 0
Arcutis Biotherapeutics Inc Common Stock 03969K108 240,920 17,184 SH SOLE 17,184 0 0
Arrowhead Pharmaceuticals Inc Common Stock 04280A100 249,656 15,801 SH SOLE 15,801 0 0
ASML Holding NV NY Reg Shrs N07059210 34,490,223 43,038 SH DFND 43,038 0 0
Autohome Inc ADR 05278C107 8,127,744 315,151 SH DFND 315,151 0 0
Broadcom Inc Common Stock 11135F101 70,917,578 257,274 SH DFND 257,274 0 0
Anavex Life Sciences Corp Common Stock 032797300 94,588 10,259 SH SOLE 10,259 0 0
Axon Enterprise Inc Common Stock 05464C101 1,699,761 2,053 SH DFND 2,053 0 0
American Express Co Common Stock 025816109 449,762 1,410 SH SOLE 1,410 0 0
AstraZeneca PLC ADR 046353108 970,423 13,887 SH DFND 13,887 0 0
Boeing Co/The Common Stock 097023105 403,345 1,925 SH SOLE 1,925 0 0
Bank of America Corp Common Stock 060505104 3,470,733 73,346 SH SOLE 73,346 0 0
Baxter International Inc Common Stock 071813109 294,412 9,723 SH SOLE 9,723 0 0
Bridgebio Pharma Inc Common Stock 10806X102 948,449 21,965 SH SOLE 21,965 0 0
BioCryst Pharmaceuticals Inc Common Stock 09058V103 300,984 33,592 SH SOLE 33,592 0 0
Becton Dickinson & Co Common Stock 075887109 388,252 2,254 SH SOLE 2,254 0 0
Beam Therapeutics Inc Common Stock 07373V105 232,612 13,675 SH SOLE 13,675 0 0
Biohaven Ltd Common Stock G1110E107 190,372 13,492 SH SOLE 13,492 0 0
Biogen Inc Common Stock 09062X103 1,734,398 13,810 SH DFND 13,810 0 0
Booking Holdings Inc Common Stock 09857L108 4,897,697 846 SH DFND 846 0 0
Baker Hughes Co Common Stock 05722G100 986,373 25,727 SH DFND 25,727 0 0
Blackrock Inc Common Stock 09290D101 392,419 374 SH SOLE 374 0 0
BioMarin Pharmaceutical Inc Common Stock 09061G101 1,031,897 18,772 SH SOLE 18,772 0 0
Bristol-Myers Squibb Co Common Stock 110122108 481,833 10,409 SH SOLE 10,409 0 0
Blueprint Medicines Corp Common Stock 09627Y109 866,625 6,761 SH SOLE 6,761 0 0
Berkshire Hathaway Inc Common Stock 084670702 7,363,787 15,159 SH SOLE 15,159 0 0
Boston Scientific Corp Common Stock 101137107 691,935 6,442 SH SOLE 6,442 0 0
Blackstone Inc Common Stock 09260D107 281,061 1,879 SH SOLE 1,879 0 0
Kanzhun Ltd ADR 48553T106 31,792,129 1,782,070 SH DFND 1,782,070 0 0
Citigroup Inc Common Stock 172967424 399,724 4,696 SH SOLE 4,696 0 0
Cardinal Health Inc Common Stock 14149Y108 390,936 2,327 SH SOLE 2,327 0 0
Caterpillar Inc Common Stock 149123101 459,252 1,183 SH SOLE 1,183 0 0
Chubb Ltd Common Stock H1467J104 279,290 964 SH SOLE 964 0 0
Coca-Cola Europacific Partners Common Stock G25839104 996,833 10,751 SH DFND 10,751 0 0
Carnival Corp Common Stock 143658300 1,445,115 51,391 SH SOLE 51,391 0 0
Cadence Design Systems Inc Common Stock 127387108 4,402,231 14,286 SH DFND 14,286 0 0
CDW Corp/DE Common Stock 12514G108 976,352 5,467 SH DFND 5,467 0 0
Constellation Energy Corp Common Stock 21037T109 2,621,457 8,122 SH DFND 8,122 0 0
Celsius Holdings Inc Common Stock 15118V207 1,034,729 22,305 SH DFND 22,305 0 0
CG oncology Inc Common Stock 156944100 232,232 8,932 SH SOLE 8,932 0 0
Charter Communications Inc Common Stock 16119P108 1,436,559 3,514 SH DFND 3,514 0 0
Cigna Group/The Common Stock 125523100 503,804 1,524 SH SOLE 1,524 0 0
Celestica Inc Common Stock 15101Q207 11,130,643 71,300 SH SOLE 71,300 0 0
Cheetah Mobile Inc ADR 163075203 333,979 71,363 SH SOLE 71,363 0 0
Comcast Corp Common Stock 20030N101 3,459,324 96,927 SH DFND 96,927 0 0
CME Group Inc Common Stock 12572Q105 254,948 925 SH SOLE 925 0 0
Centene Corp Common Stock 15135B101 325,626 5,999 SH SOLE 5,999 0 0
Capital One Financial Corp Common Stock 14040H105 349,565 1,643 SH SOLE 1,643 0 0
Cogent Biosciences Inc Common Stock 19240Q201 73,272 10,205 SH SOLE 10,205 0 0
Coherent Corp Common Stock 19247G107 624,470 7,000 SH SOLE 7,000 0 0
Coinbase Global Inc Common Stock 19260Q107 1,076,355 3,071 SH DFND 3,071 0 0
Cooper Cos Inc/The Common Stock 216648501 297,876 4,186 SH SOLE 4,186 0 0
ConocoPhillips Common Stock 20825C104 290,040 3,232 SH SOLE 3,232 0 0
Cencora Inc Common Stock 03073E105 408,096 1,361 SH SOLE 1,361 0 0
Costco Wholesale Corp Common Stock 22160K105 14,854,050 15,005 SH DFND 15,005 0 0
Copart Inc Common Stock 217204106 1,215,267 24,766 SH DFND 24,766 0 0
Catalyst Pharmaceuticals Inc Common Stock 14888U101 231,235 10,656 SH SOLE 10,656 0 0
Credo Technology Group Holding Common Stock G25457105 294,899 3,185 SH SOLE 3,185 0 0
Charles River Laboratories Int Common Stock 159864107 284,342 1,874 SH SOLE 1,874 0 0
Salesforce Inc Common Stock 79466L302 6,909,965 25,340 SH SOLE 25,340 0 0
Crinetics Pharmaceuticals Inc Common Stock 22663K107 291,368 10,131 SH SOLE 10,131 0 0
CRISPR Therapeutics AG Common Stock H17182108 620,841 12,764 SH SOLE 12,764 0 0
Crowdstrike Holdings Inc Common Stock 22788C105 5,322,290 10,450 SH DFND 10,450 0 0
Cisco Systems Inc Common Stock 17275R102 13,731,342 197,915 SH DFND 197,915 0 0
CoStar Group Inc Common Stock 22160N109 879,897 10,944 SH DFND 10,944 0 0
CSX Corp Common Stock 126408103 1,591,006 48,759 SH DFND 48,759 0 0
Cintas Corp Common Stock 172908105 2,307,150 10,352 SH DFND 10,352 0 0
Cognizant Technology Solutions Common Stock 192446102 1,627,940 20,863 SH DFND 20,863 0 0
CVS Health Corp Common Stock 126650100 495,621 7,185 SH SOLE 7,185 0 0
Chevron Corp Common Stock 166764100 2,461,150 17,188 SH SOLE 17,188 0 0
China Yuchai International Ltd Common Stock G21082105 205,937 8,613 SH DFND 8,613 0 0
Cytokinetics Inc Common Stock 23282W605 625,084 18,919 SH SOLE 18,919 0 0
DoorDash Inc Common Stock 25809K105 2,665,020 10,811 SH DFND 10,811 0 0
Day One Biopharmaceuticals Inc Common Stock 23954D109 71,422 10,988 SH SOLE 10,988 0 0
Invesco DB Oil Fund ETP 46140H403 11,044,953 835,473 SH SOLE 835,473 0 0
Datadog Inc Common Stock 23804L103 2,900,722 21,594 SH DFND 21,594 0 0
Deere & Co Common Stock 244199105 330,518 650 SH SOLE 650 0 0
Dell Technologies Inc Common Stock 24703L202 681,166 5,556 SH SOLE 5,556 0 0
Quest Diagnostics Inc Common Stock 74834L100 314,712 1,752 SH SOLE 1,752 0 0
Danaher Corp Common Stock 235851102 571,483 2,893 SH SOLE 2,893 0 0
Walt Disney Co/The Common Stock 254687106 2,329,280 18,783 SH SOLE 18,783 0 0
Denali Therapeutics Inc Common Stock 24823R105 190,432 13,612 SH SOLE 13,612 0 0
Duke Energy Corp Common Stock 26441C204 230,572 1,954 SH SOLE 1,954 0 0
DaVita Inc Common Stock 23918K108 284,188 1,995 SH SOLE 1,995 0 0
Dynavax Technologies Corp Common Stock 268158201 179,681 18,113 SH SOLE 18,113 0 0
Dexcom Inc Common Stock 252131107 1,156,243 13,246 SH DFND 13,246 0 0
Dyne Therapeutics Inc Common Stock 26818M108 116,848 12,274 SH SOLE 12,274 0 0
Electronic Arts Inc Common Stock 285512109 1,026,232 6,426 SH DFND 6,426 0 0
Elevance Health Inc Common Stock 036752103 486,200 1,250 SH SOLE 1,250 0 0
Equinix Inc REIT 29444U700 202,049 254 SH SOLE 254 0 0
Eaton Corp PLC Common Stock G29183103 355,562 996 SH SOLE 996 0 0
89bio Inc Common Stock 282559103 133,768 13,622 SH SOLE 13,622 0 0
Edwards Lifesciences Corp Common Stock 28176E108 392,614 5,020 SH SOLE 5,020 0 0
Exact Sciences Corp Common Stock 30063P105 1,024,433 19,278 SH SOLE 19,278 0 0
Exelon Corp Common Stock 30161N101 1,131,786 26,066 SH DFND 26,066 0 0
Exelixis Inc Common Stock 30161Q104 1,141,498 25,899 SH SOLE 25,899 0 0
Ford Motor Co Common Stock 345370860 110,757 10,208 SH SOLE 10,208 0 0
Diamondback Energy Inc Common Stock 25278X109 1,003,981 7,307 SH DFND 7,307 0 0
Fastenal Co Common Stock 311900104 1,255,002 29,881 SH DFND 29,881 0 0
F5 Inc Common Stock 315616102 329,638 1,120 SH SOLE 1,120 0 0
Fiserv Inc Common Stock 337738108 247,064 1,433 SH SOLE 1,433 0 0
Fair Isaac Corp Common Stock 303250104 822,582 450 SH SOLE 450 0 0
Amicus Therapeutics Inc Common Stock 03152W109 265,448 46,326 SH SOLE 46,326 0 0
First Solar Inc Common Stock 336433107 342,502 2,069 SH SOLE 2,069 0 0
Fortinet Inc Common Stock 34959E109 3,150,562 29,801 SH DFND 29,801 0 0
Futu Holdings Ltd ADR 36118L106 8,765,868 70,927 SH DFND 70,927 0 0
GoDaddy Inc Common Stock 380237107 482,021 2,677 SH SOLE 2,677 0 0
General Electric Co Common Stock 369604301 2,996,277 11,641 SH DFND 11,641 0 0
GE HealthCare Technologies Inc Common Stock 36266G107 1,140,901 15,403 SH DFND 15,403 0 0
Gen Digital Inc Common Stock 668771108 305,995 10,408 SH SOLE 10,408 0 0
Geron Corp Common Stock 374163103 130,056 92,238 SH SOLE 92,238 0 0
GE Vernova Inc Common Stock 36828A101 367,759 695 SH SOLE 695 0 0
GLOBALFOUNDRIES Inc Common Stock G39387108 489,189 12,806 SH DFND 12,806 0 0
Gilead Sciences Inc Common Stock 375558103 4,941,143 44,567 SH DFND 44,567 0 0
SPDR Gold Shares ETP 78463V107 23,638,347 77,546 SH SOLE 77,546 0 0
SPDR Gold MiniShares Trust ETP 98149E303 23,647,151 360,915 SH SOLE 360,915 0 0
Corning Inc Common Stock 219350105 752,353 14,306 SH SOLE 14,306 0 0
Alphabet Inc Common Stock 02079K107 18,303,810 103,184 SH DFND 103,184 0 0
Alphabet Inc Common Stock 02079K305 23,380,435 132,670 SH DFND 132,670 0 0
GRAIL Inc Common Stock 384747101 234,938 4,569 SH SOLE 4,569 0 0
Goldman Sachs Group Inc/The Common Stock 38141G104 2,278,247 3,219 SH SOLE 3,219 0 0
Halozyme Therapeutics Inc Common Stock 40637H109 1,036,551 19,926 SH SOLE 19,926 0 0
HCA Healthcare Inc Common Stock 40412C101 448,227 1,170 SH SOLE 1,170 0 0
Home Depot Inc/The Common Stock 437076102 3,785,191 10,324 SH SOLE 10,324 0 0
Hilton Worldwide Holdings Inc Common Stock 43300A203 2,197,571 8,251 SH SOLE 8,251 0 0
Hologic Inc Common Stock 436440101 302,733 4,646 SH SOLE 4,646 0 0
Honeywell International Inc Common Stock 438516106 3,886,767 16,690 SH DFND 16,690 0 0
Robinhood Markets Inc Common Stock 770700102 280,984 3,001 SH DFND 3,001 0 0
Hewlett Packard Enterprise Co Common Stock 42824C109 507,794 24,831 SH SOLE 24,831 0 0
HP Inc Common Stock 40434L105 432,233 17,671 SH SOLE 17,671 0 0
Henry Schein Inc Common Stock 806407102 299,140 4,095 SH SOLE 4,095 0 0
H World Group Ltd ADR 44332N106 2,822,721 83,217 SH DFND 83,217 0 0
Humana Inc Common Stock 444859102 352,540 1,442 SH SOLE 1,442 0 0
Humacyte Inc Common Stock 44486Q103 43,106 20,625 SH SOLE 20,625 0 0
HUYA Inc ADR 44852D108 36,604 10,399 SH SOLE 10,399 0 0
iShares Gold Trust ETP 464285204 23,835,738 382,228 SH SOLE 382,228 0 0
Interactive Brokers Group Inc Common Stock 45841N107 1,108,200 20,000 SH SOLE 20,000 0 0
International Business Machine Common Stock 459200101 7,225,647 24,512 SH SOLE 24,512 0 0
ImmunityBio Inc Common Stock 45256X103 74,205 28,108 SH SOLE 28,108 0 0
Intercontinental Exchange Inc Common Stock 45866F104 265,481 1,447 SH SOLE 1,447 0 0
IDEXX Laboratories Inc Common Stock 45168D104 1,391,266 2,594 SH DFND 2,594 0 0
Ideaya Biosciences Inc Common Stock 45166A102 256,969 12,225 SH SOLE 12,225 0 0
Immunovant Inc Common Stock 45258J102 189,664 11,854 SH SOLE 11,854 0 0
Incyte Corp Common Stock 45337C102 1,356,007 19,912 SH SOLE 19,912 0 0
Insmed Inc Common Stock 457669307 1,102,109 10,951 SH SOLE 10,951 0 0
Intel Corp Common Stock 458140100 4,341,255 193,806 SH DFND 193,806 0 0
Intuit Inc Common Stock 461202103 10,963,810 13,920 SH DFND 13,920 0 0
Ionis Pharmaceuticals Inc Common Stock 462222100 638,482 16,160 SH SOLE 16,160 0 0
Iovance Biotherapeutics Inc Common Stock 462260100 56,001 32,559 SH SOLE 32,559 0 0
iQIYI Inc ADR 46267X108 3,726,080 2,105,130 SH SOLE 2,105,130 0 0
IQVIA Holdings Inc Common Stock 46266C105 330,781 2,099 SH SOLE 2,099 0 0
Intuitive Surgical Inc Common Stock 46120E602 6,862,181 12,628 SH DFND 12,628 0 0
Gartner Inc Common Stock 366651107 591,374 1,463 SH SOLE 1,463 0 0
iShares Core S&P 500 ETF ETP 464287200 19,771,940 31,844 SH SOLE 31,844 0 0
Jabil Inc Common Stock 466313103 427,040 1,958 SH SOLE 1,958 0 0
Johnson Controls International Common Stock G51502105 1,037,611 9,824 SH DFND 9,824 0 0
Johnson & Johnson Common Stock 478160104 4,081,785 26,722 SH SOLE 26,722 0 0
Juniper Networks Inc Common Stock 48203R104 249,682 6,253 SH SOLE 6,253 0 0
JOYY Inc ADR 46591M109 6,548,349 128,626 SH DFND 128,626 0 0
JPMorgan Chase & Co Common Stock 46625H100 8,407,100 28,999 SH SOLE 28,999 0 0
Keurig Dr Pepper Inc Common Stock 49271V100 1,160,671 35,108 SH DFND 35,108 0 0
Keysight Technologies Inc Common Stock 49338L103 539,263 3,291 SH SOLE 3,291 0 0
Kraft Heinz Co/The Common Stock 500754106 767,887 29,740 SH DFND 29,740 0 0
KKR & Co Inc Common Stock 48251W104 234,665 1,764 SH SOLE 1,764 0 0
KLA Corp Common Stock 482480100 29,164,399 32,559 SH DFND 32,559 0 0
Coca-Cola Co/The Common Stock 191216100 2,971,005 41,993 SH SOLE 41,993 0 0
Krystal Biotech Inc Common Stock 501147102 531,970 3,870 SH SOLE 3,870 0 0
Kura Oncology Inc Common Stock 50127T109 67,521 11,702 SH SOLE 11,702 0 0
Legend Biotech Corp ADR 52490G102 927,425 26,132 SH SOLE 26,132 0 0
Labcorp Holdings Inc Common Stock 504922105 323,150 1,231 SH SOLE 1,231 0 0
Linde PLC Common Stock G54950103 7,489,051 15,962 SH DFND 15,962 0 0
Eli Lilly & Co Common Stock 532457108 6,742,155 8,649 SH SOLE 8,649 0 0
Lockheed Martin Corp Common Stock 539830109 251,022 542 SH SOLE 542 0 0
Lowe's Cos Inc Common Stock 548661107 318,162 1,434 SH SOLE 1,434 0 0
Lam Research Corp Common Stock 512807306 5,226,671 53,695 SH DFND 53,695 0 0
Lululemon Athletica Inc Common Stock 550021109 704,425 2,965 SH DFND 2,965 0 0
Las Vegas Sands Corp Common Stock 517834107 243,438 5,595 SH SOLE 5,595 0 0
Mastercard Inc Common Stock 57636Q104 4,755,136 8,462 SH SOLE 8,462 0 0
Marriott International Inc/MD Common Stock 571903202 3,873,844 14,179 SH DFND 14,179 0 0
McDonald's Corp Common Stock 580135101 2,171,992 7,434 SH SOLE 7,434 0 0
Microchip Technology Inc Common Stock 595017104 1,591,559 22,617 SH DFND 22,617 0 0
McKesson Corp Common Stock 58155Q103 503,420 687 SH SOLE 687 0 0
Moody's Corp Common Stock 615369105 936,469 1,867 SH SOLE 1,867 0 0
Madrigal Pharmaceuticals Inc Common Stock 558868105 828,931 2,739 SH SOLE 2,739 0 0
Mondelez International Inc Common Stock 609207105 2,271,042 33,675 SH DFND 33,675 0 0
Medtronic PLC Common Stock G5960L103 545,510 6,258 SH SOLE 6,258 0 0
MercadoLibre Inc Common Stock 58733R102 3,107,606 1,189 SH DFND 1,189 0 0
Meta Platforms Inc Common Stock 30303M102 37,926,017 51,384 SH DFND 51,384 0 0
Mirum Pharmaceuticals Inc Common Stock 604749101 210,837 4,143 SH SOLE 4,143 0 0
Marsh & McLennan Cos Inc Common Stock 571748102 272,863 1,248 SH SOLE 1,248 0 0
3M Co Common Stock 88579Y101 208,112 1,367 SH SOLE 1,367 0 0
MannKind Corp Common Stock 56400P706 97,973 26,196 SH SOLE 26,196 0 0
Monster Beverage Corp Common Stock 61174X109 1,532,300 24,462 SH DFND 24,462 0 0
Altria Group Inc Common Stock 02209S103 255,040 4,350 SH SOLE 4,350 0 0
Molina Healthcare Inc Common Stock 60855R100 314,582 1,056 SH SOLE 1,056 0 0
Hello Group Inc ADR 423403104 761,516 90,227 SH SOLE 90,227 0 0
Monolithic Power Systems Inc Common Stock 609839105 674,332 922 SH SOLE 922 0 0
Merck & Co Inc Common Stock 58933Y105 2,328,333 29,413 SH SOLE 29,413 0 0
Moderna Inc Common Stock 60770K107 1,348,185 48,865 SH SOLE 48,865 0 0
Marvell Technology Inc Common Stock 573874104 1,741,268 22,497 SH DFND 22,497 0 0
Morgan Stanley Common Stock 617446448 442,723 3,143 SH SOLE 3,143 0 0
MSCI Inc Common Stock 55354G100 209,357 363 SH DFND 363 0 0
Microsoft Corp Common Stock 594918104 172,388,876 346,573 SH DFND 346,573 0 0
Motorola Solutions Inc Common Stock 620076307 1,306,369 3,107 SH SOLE 3,107 0 0
MicroStrategy Inc Common Stock 594972408 2,404,764 5,949 SH DFND 5,949 0 0
Mettler-Toledo International I Common Stock 592688105 318,349 271 SH SOLE 271 0 0
Micron Technology Inc Common Stock 595112103 7,927,440 64,320 SH DFND 64,320 0 0
Myriad Genetics Inc Common Stock 62855J104 66,773 12,575 SH SOLE 12,575 0 0
Neurocrine Biosciences Inc Common Stock 64125C109 1,086,213 8,642 SH SOLE 8,642 0 0
NextEra Energy Inc Common Stock 65339F101 366,329 5,277 SH SOLE 5,277 0 0
Cloudflare Inc Common Stock 18915M107 2,270,453 11,594 SH SOLE 11,594 0 0
Netflix Inc Common Stock 64110L106 23,904,809 17,851 SH DFND 17,851 0 0
Niu Technologies ADR 65481N100 53,760 16,000 SH SOLE 16,000 0 0
NIKE Inc Common Stock 654106103 217,453 3,061 SH SOLE 3,061 0 0
ServiceNow Inc Common Stock 81762P102 11,406,548 11,095 SH DFND 11,095 0 0
NetApp Inc Common Stock 64110D104 389,227 3,653 SH SOLE 3,653 0 0
Intellia Therapeutics Inc Common Stock 45826J105 134,500 14,339 SH SOLE 14,339 0 0
Natera Inc Common Stock 632307104 1,087,129 6,435 SH SOLE 6,435 0 0
Nuvalent Inc Common Stock 670703107 412,096 5,401 SH SOLE 5,401 0 0
Novavax Inc Common Stock 670002401 178,164 28,280 SH SOLE 28,280 0 0
NVIDIA Corp Common Stock 67066G104 150,809,828 954,553 SH DFND 954,553 0 0
NXP Semiconductors NV Common Stock N6596X109 2,315,557 10,598 SH DFND 10,598 0 0
Old Dominion Freight Line Inc Common Stock 679580100 875,933 5,397 SH DFND 5,397 0 0
ON Semiconductor Corp Common Stock 682189105 1,615,958 30,833 SH DFND 30,833 0 0
Oracle Corp Common Stock 68389X105 13,945,096 63,784 SH DFND 63,784 0 0
O'Reilly Automotive Inc Common Stock 67103H107 2,004,852 22,244 SH DFND 22,244 0 0
Palo Alto Networks Inc Common Stock 697435105 5,715,186 27,928 SH DFND 27,928 0 0
Paychex Inc Common Stock 704326107 1,345,214 9,248 SH DFND 9,248 0 0
PACCAR Inc Common Stock 693718108 1,298,805 13,663 SH DFND 13,663 0 0
Vaxcyte Inc Common Stock 92243G108 598,119 18,398 SH SOLE 18,398 0 0
PDD Holdings Inc ADR 722304102 356,233,439 3,403,721 SH DFND 3,403,721 0 0
PepsiCo Inc Common Stock 713448108 6,126,524 46,399 SH DFND 46,399 0 0
Pfizer Inc Common Stock 717081103 614,169 25,337 SH SOLE 25,337 0 0
Procter & Gamble Co/The Common Stock 742718109 3,881,672 24,364 SH SOLE 24,364 0 0
Progressive Corp/The Common Stock 743315103 401,357 1,504 SH SOLE 1,504 0 0
Parker-Hannifin Corp Common Stock 701094104 224,907 322 SH SOLE 322 0 0
Prologis Inc REIT 74340W103 250,080 2,379 SH SOLE 2,379 0 0
Palantir Technologies Inc Common Stock 69608A108 16,824,341 123,418 SH DFND 123,418 0 0
Philip Morris International In Common Stock 718172109 2,949,049 16,192 SH SOLE 16,192 0 0
Insulet Corp Common Stock 45784P101 324,548 1,033 SH SOLE 1,033 0 0
PTC Inc Common Stock 69370C100 394,142 2,287 SH SOLE 2,287 0 0
PTC Therapeutics Inc Common Stock 69366J200 532,258 10,898 SH SOLE 10,898 0 0
Protagonist Therapeutics Inc Common Stock 74366E102 496,877 8,990 SH SOLE 8,990 0 0
PayPal Holdings Inc Common Stock 70450Y103 1,867,067 25,122 SH DFND 25,122 0 0
QUALCOMM Inc Common Stock 747525103 8,730,474 54,819 SH DFND 54,819 0 0
Qifu Technology Inc ADR 88557W101 23,098,262 532,709 SH DFND 532,709 0 0
Ultragenyx Pharmaceutical Inc Common Stock 90400D108 329,131 9,052 SH SOLE 9,052 0 0
ROBLOX Corp Common Stock 771049103 1,545,914 14,695 SH DFND 14,695 0 0
Rubrik Inc Common Stock 781154109 1,139,585 12,720 SH DFND 12,720 0 0
Royal Caribbean Cruises Ltd Common Stock V7780T103 3,370,326 10,763 SH DFND 10,763 0 0
Arcus Biosciences Inc Common Stock 03969F109 89,434 10,987 SH SOLE 10,987 0 0
Reddit Inc Common Stock 75734B100 452,613 3,006 SH DFND 3,006 0 0
Regeneron Pharmaceuticals Inc Common Stock 75886F107 2,797,725 5,329 SH DFND 5,329 0 0
ATRenew Inc ADR 00138L108 405,607 122,540 SH SOLE 122,540 0 0
Ralph Lauren Corp Common Stock 751212101 587,782 2,143 SH SOLE 2,143 0 0
Relay Therapeutics Inc Common Stock 75943R102 70,093 20,258 SH SOLE 20,258 0 0
ResMed Inc Common Stock 761152107 369,456 1,432 SH SOLE 1,432 0 0
Avidity Biosciences Inc Common Stock 05370A108 402,229 14,163 SH SOLE 14,163 0 0
Roivant Sciences Ltd Common Stock G76279101 743,302 65,954 SH SOLE 65,954 0 0
Roper Technologies Inc Common Stock 776696106 2,558,149 4,513 SH DFND 4,513 0 0
Ross Stores Inc Common Stock 778296103 1,082,517 8,485 SH DFND 8,485 0 0
RTX Corp Common Stock 75513E101 489,897 3,355 SH SOLE 3,355 0 0
Revolution Medicines Inc Common Stock 76155X100 628,189 17,075 SH SOLE 17,075 0 0
Revvity Inc Common Stock 714046109 300,219 3,104 SH SOLE 3,104 0 0
Recursion Pharmaceuticals Inc Common Stock 75629V104 200,644 39,653 SH SOLE 39,653 0 0
Rhythm Pharmaceuticals Inc Common Stock 76243J105 364,038 5,761 SH SOLE 5,761 0 0
SAP SE ADR 803054204 1,595,005 5,245 SH DFND 5,245 0 0
Starbucks Corp Common Stock 855244109 2,711,423 29,591 SH DFND 29,591 0 0
Charles Schwab Corp/The Common Stock 808513105 394,887 4,328 SH SOLE 4,328 0 0
Sea Ltd ADR 81141R100 1,634,587 10,220 SH DFND 10,220 0 0
ETFS GOLD TR PHYSCL GOLD SHS 00326A104 23,758,798 753,291 SH SOLE 753,291 0 0
Shopify Inc Common Stock 82509L107 3,228,877 27,992 SH SOLE 27,992 0 0
Sherwin-Williams Co/The Common Stock 824348106 204,299 595 SH SOLE 595 0 0
Soleno Therapeutics Inc Common Stock 834203309 443,280 5,291 SH SOLE 5,291 0 0
Super Micro Computer Inc Common Stock 86800U302 446,432 9,109 SH SOLE 9,109 0 0
Summit Therapeutics Inc Common Stock 86627T108 472,331 22,196 SH SOLE 22,196 0 0
Syndax Pharmaceuticals Inc Common Stock 87164F105 131,419 14,033 SH SOLE 14,033 0 0
Synopsys Inc Common Stock 871607107 3,329,857 6,495 SH DFND 6,495 0 0
Southern Co/The Common Stock 842587107 258,226 2,812 SH SOLE 2,812 0 0
Sohu.com Ltd ADR 83410S108 911,416 68,476 SH SOLE 68,476 0 0
Solventum Corp Common Stock 83444M101 300,326 3,960 SH SOLE 3,960 0 0
S&P Global Inc Common Stock 78409V104 849,992 1,612 SH DFND 1,612 0 0
SPDR S&P 500 ETF Trust ETP 78462F103 10,014,731 16,209 SH SOLE 16,209 0 0
Sarepta Therapeutics Inc Common Stock 803607100 282,577 16,525 SH SOLE 16,525 0 0
Scholar Rock Holding Corp Common Stock 80706P103 394,791 11,146 SH SOLE 11,146 0 0
STERIS PLC Common Stock G8473T100 322,615 1,343 SH SOLE 1,343 0 0
Seagate Technology Holdings PL Common Stock G7997R103 590,021 4,088 SH SOLE 4,088 0 0
SpringWorks Therapeutics Inc Common Stock 85205L107 596,444 12,693 SH SOLE 12,693 0 0
Stryker Corp Common Stock 863667101 619,557 1,566 SH SOLE 1,566 0 0
AT&T Inc Common Stock 00206R102 2,162,918 74,738 SH SOLE 74,738 0 0
TAL Education Group ADR 874080104 19,712,397 1,928,806 SH DFND 1,928,806 0 0
TransDigm Group Inc Common Stock 893641100 222,013 146 SH SOLE 146 0 0
Teledyne Technologies Inc Common Stock 879360105 454,931 888 SH SOLE 888 0 0
Atlassian Corp Common Stock 049468101 781,897 3,850 SH DFND 3,850 0 0
Bio-Techne Corp Common Stock 09073M104 282,821 5,497 SH SOLE 5,497 0 0
TE Connectivity PLC Common Stock G87052109 948,431 5,623 SH SOLE 5,623 0 0
Teradyne Inc Common Stock 880770102 256,722 2,855 SH SOLE 2,855 0 0
TG Therapeutics Inc Common Stock 88322Q108 756,114 21,009 SH SOLE 21,009 0 0
TJX Cos Inc/The Common Stock 872540109 352,564 2,855 SH SOLE 2,855 0 0
ISHARES TR 20 YR TR BD ETF 464287432 725,239 8,218 SH SOLE 8,218 0 0
Tencent Music Entertainment Gr ADR 88034P109 51,037,138 2,618,632 SH DFND 2,618,632 0 0
Thermo Fisher Scientific Inc Common Stock 883556102 647,114 1,596 SH SOLE 1,596 0 0
T-Mobile US Inc Common Stock 872590104 6,634,350 27,845 SH DFND 27,845 0 0
Toll Brothers Inc Common Stock 889478103 543,031 4,758 SH SOLE 4,758 0 0
Tapestry Inc Common Stock 876030107 1,119,051 12,744 SH SOLE 12,744 0 0
Trimble Inc Common Stock 896239100 354,295 4,663 SH SOLE 4,663 0 0
Taysha Gene Therapies Inc Common Stock 877619106 30,524 13,214 SH SOLE 13,214 0 0
Tesla Inc Common Stock 88160R101 23,264,148 73,236 SH DFND 73,236 0 0
Taiwan Semiconductor Manufactu ADR 874039100 43,473,623 191,945 SH DFND 191,945 0 0
Trane Technologies PLC Common Stock G8994E103 247,137 565 SH SOLE 565 0 0
Trade Desk Inc/The Common Stock 88339J105 750,136 10,420 SH DFND 10,420 0 0
Take-Two Interactive Software Common Stock 874054109 1,308,719 5,389 SH DFND 5,389 0 0
Travere Therapeutics Inc Common Stock 89422G107 204,077 13,789 SH SOLE 13,789 0 0
Twist Bioscience Corp Common Stock 90184D100 310,692 8,445 SH SOLE 8,445 0 0
Texas Instruments Inc Common Stock 882508104 7,920,496 38,149 SH DFND 38,149 0 0
Tyler Technologies Inc Common Stock 902252105 478,422 807 SH SOLE 807 0 0
Uber Technologies Inc Common Stock 90353T100 494,956 5,305 SH SOLE 5,305 0 0
Universal Health Services Inc Common Stock 913903100 308,136 1,701 SH SOLE 1,701 0 0
UnitedHealth Group Inc Common Stock 91324P102 3,230,761 10,356 SH SOLE 10,356 0 0
Union Pacific Corp Common Stock 907818108 353,173 1,535 SH SOLE 1,535 0 0
United Therapeutics Corp Common Stock 91307C102 1,115,205 3,881 SH SOLE 3,881 0 0
Visa Inc Common Stock 92826C839 6,344,033 17,868 SH SOLE 17,868 0 0
Vericel Corp Common Stock 92346J108 224,962 5,287 SH SOLE 5,287 0 0
Veracyte Inc Common Stock 92337F107 328,333 12,147 SH SOLE 12,147 0 0
Vipshop Holdings Ltd ADR 92763W103 21,769,208 1,446,459 SH DFND 1,446,459 0 0
Vir Biotechnology Inc Common Stock 92764N102 74,078 14,698 SH SOLE 14,698 0 0
Viking Therapeutics Inc Common Stock 92686J106 465,870 17,580 SH SOLE 17,580 0 0
Vanguard S&P 500 ETF ETP 922908363 531,108 935 SH SOLE 935 0 0
Verisk Analytics Inc Common Stock 92345Y106 1,139,467 3,658 SH DFND 3,658 0 0
VeriSign Inc Common Stock 92343E102 445,330 1,542 SH SOLE 1,542 0 0
Vertiv Holdings Co Common Stock 92537N108 1,264,068 9,844 SH DFND 9,844 0 0
Vertex Pharmaceuticals Inc Common Stock 92532F100 4,286,386 9,628 SH DFND 9,628 0 0
Verastem Inc Common Stock 92337C203 48,555 11,700 SH SOLE 11,700 0 0
Viatris Inc Common Stock 92556V106 287,894 32,239 SH SOLE 32,239 0 0
Verizon Communications Inc Common Stock 92343V104 1,896,135 43,821 SH SOLE 43,821 0 0
Waters Corp Common Stock 941848103 316,928 908 SH SOLE 908 0 0
Weibo Corp ADR 948596101 3,400,390 356,809 SH SOLE 356,809 0 0
Warner Bros Discovery Inc Common Stock 934423104 718,691 62,713 SH DFND 62,713 0 0
Workday Inc Common Stock 98138H101 2,195,760 9,149 SH DFND 9,149 0 0
Western Digital Corp Common Stock 958102105 426,301 6,662 SH SOLE 6,662 0 0
Waterdrop Inc ADR 94132V105 371,686 275,323 SH SOLE 275,323 0 0
Welltower Inc REIT 95040Q104 235,976 1,535 SH SOLE 1,535 0 0
Wells Fargo & Co Common Stock 949746101 2,712,783 33,859 SH SOLE 33,859 0 0
Waste Management Inc Common Stock 94106L109 205,938 900 SH SOLE 900 0 0
Walmart Inc Common Stock 931142103 4,462,190 45,635 SH SOLE 45,635 0 0
Williams-Sonoma Inc Common Stock 969904101 883,995 5,411 SH SOLE 5,411 0 0
West Pharmaceutical Services I Common Stock 955306105 293,848 1,343 SH SOLE 1,343 0 0
Xcel Energy Inc Common Stock 98389B100 1,019,798 14,975 SH DFND 14,975 0 0
Xencor Inc Common Stock 98401F105 79,284 10,087 SH SOLE 10,087 0 0
Exxon Mobil Corp Common Stock 30231G102 4,838,819 44,887 SH SOLE 44,887 0 0
Yalla Group Ltd ADR 98459U103 380,419 56,442 SH SOLE 56,442 0 0
Full Truck Alliance Co Ltd ADR 35969L108 45,004,674 3,810,726 SH SOLE 3,810,726 0 0
Yum China Holdings Inc Common Stock 98850P109 6,816,218 152,454 SH SOLE 152,454 0 0
Zimmer Biomet Holdings Inc Common Stock 98956P102 297,801 3,265 SH SOLE 3,265 0 0
Zebra Technologies Corp Common Stock 989207105 279,374 906 SH SOLE 906 0 0
Zhihu Inc ADR 98955N207 777,943 195,463 SH SOLE 195,463 0 0
Zscaler Inc Common Stock 98980G102 4,751,796 15,136 SH DFND 15,136 0 0
Zoetis Inc Common Stock 98978V103 428,707 2,749 SH SOLE 2,749 0 0
Cboe Global Markets Inc Common Stock 12503M108 59,702 256 SH SOLE 256 0 0
iShares MSCI Eurozone ETF ETP 464286608 385,295 6,481 SH SOLE 6,481 0 0