The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4DMOLECULARTHERAPEUTICSIN COM 35104E100 44,520 12,000 SH SOLE 12,000 0 0
ACLARISTHERAPEUTICSINC COM 00461U105 46,434 32,700 SH SOLE 32,700 0 0
ALECTORINC COM 014442107 77,000 55,000 SH SOLE 55,000 0 0
ALUMISINC COM 022307102 4,862,538 1,620,846 SH SOLE 1,620,846 0 0
ARVINASINC COM 04335A105 3,680,000 500,000 SH SOLE 500,000 0 0
AVALOTHERAPEUTICSINC COMNEW 05338F306 773,310 154,972 SH SOLE 154,972 0 0
CIDARATHERAPEUTICSINC COMNEW 171757206 4,871,000 100,000 SH SOLE 100,000 0 0
CONTEXTTHERAPEUTICSINC COM 21077P108 65,520 100,000 SH SOLE 100,000 0 0
CORBUSPHARMACEUTICALSHLDGS COMNEW 21833P301 407,100 59,000 SH SOLE 59,000 0 0
CYTOMXTHERAPEUTICSINC COM 23284F105 170,250 75,000 SH SOLE 75,000 0 0
DESIGNTHERAPEUTICSINC COM 25056L103 67,400 20,000 SH SOLE 20,000 0 0
EDESABIOTECHINC COMNEW 27966L306 507,500 250,000 SH OTR 0 250,000 0
EDESABIOTECHINC COMNEW 27966L306 888,125 437,500 SH SOLE 437,500 0 0
ELEDONPHARMACEUTICALSINC COM 28617K101 918,617 338,973 SH SOLE 338,973 0 0
ERASCAINC COM 29479A108 82,550 65,000 SH SOLE 65,000 0 0
GERONCORP COM 374163103 98,700 70,000 SH SOLE 70,000 0 0
GOSSAMERBIOINC COM 38341P102 92,250 75,000 SH SOLE 75,000 0 0
HERONTHERAPEUTICSINC COM 427746102 14,462,560 6,986,744 SH SOLE 6,986,744 0 0
IMMIXBIOPHARMAINC COM 45258H106 51,750 25,000 SH SOLE 25,000 0 0
INSPIREMDINC COM 45779A846 2,052,146 904,029 SH SOLE 904,029 0 0
JASPERTHERAPEUTICSINC COMNEW 471871202 6,596,175 1,188,500 SH SOLE 1,188,500 0 0
JASPERTHERAPEUTICSINC COMNEW 471871202 1,361,570 245,328 SH OTR 0 245,328 0
KIORAPHARMACEUTICALSINC COM 49721T507 352,002 122,223 SH SOLE 122,223 0 0
LARIMARTHERAPEUTICSINC COM 517125100 95,370 33,000 SH SOLE 33,000 0 0
LIQUIDIACORPORATION COMNEW 53635D202 2,981,180 239,260 SH SOLE 239,260 0 0
MINERALYSTHERAPEUTICSINC COM 603170101 2,362,338 174,600 SH SOLE 174,600 0 0
NEKTARTHERAPEUTICS CALL 640268906 1,292,000 50,000 SH Call SOLE 50,000 0 0
NEXTCUREINC COM 65343E108 20,700 45,000 SH SOLE 45,000 0 0
NURIXTHERAPEUTICSINC COM 67080M103 113,900 10,000 SH SOLE 10,000 0 0
OVIDTHERAPEUTICSINC COM 690469101 52,784 160,000 SH SOLE 160,000 0 0
PERSPECTIVETHERAPEUTICSINC COMNEW 46489V302 1,720,000 500,000 SH SOLE 500,000 0 0
PMVPHARMACEUTICALSINC COM 69353Y103 37,100 35,000 SH SOLE 35,000 0 0
PRAXISPRECISIONMEDICINESI COMNEW 74006W207 6,279,495 149,334 SH SOLE 149,334 0 0
PROQRTHRAPEUTICSNV SHSEURO N71542109 91,800 45,000 SH SOLE 45,000 0 0
PROTAGONISTTHERAPEUTICSINC COM 74366E102 204,499 3,700 SH SOLE 3,700 0 0
PROTARATHERAPEUTICSINC COMSTK 74365U107 6,481,170 2,139,000 SH SOLE 2,139,000 0 0
PYXISONCOLOGYINC COMMONSTOCK 747324101 44,000 40,000 SH SOLE 40,000 0 0
REPLIMUNEGROUPINC COM 76029N106 1,700,841 183,083 SH SOLE 183,083 0 0
REZOLUTEINC COMNEW 76200L309 3,345,000 750,000 SH SOLE 750,000 0 0
SCPHARMACEUTICALSINC COM 810648105 3,496,315 917,668 SH SOLE 917,668 0 0
SUTROBIOPHARMAINC COM 869367102 2,184,534 3,060,000 SH SOLE 3,060,000 0 0
TELABIOINC COM 872381108 1,449,975 747,410 SH SOLE 747,410 0 0
TENAXTHERAPEUTICSINC COMNEW 88032L605 479,998 83,333 SH SOLE 83,333 0 0
TERNSPHARMACEUTICALSINC COM 880881107 74,600 20,000 SH SOLE 20,000 0 0
TOURMALINEBIOINC COM 89157D105 5,102,089 319,080 SH OTR 0 319,080 0
TOURMALINEBIOINC COM 89157D105 1,196,196 74,809 SH SOLE 74,809 0 0
UPSTREAMBIOINC COM 91678A107 1,174,860 107,000 SH SOLE 107,000 0 0
VENTYXBIOSCIENCESINC COM 92332V107 85,600 40,000 SH SOLE 40,000 0 0
VERONAPHARMAPLC SPONSOREDADS 925050106 8,985,100 95,000 SH SOLE 95,000 0 0
VIRIDIANTHERAPEUTICSINC COM 92790C104 1,209,270 86,500 SH SOLE 86,500 0 0
VYNETHERAPEUTICSINC COM 92941V308 49,500 30,000 SH SOLE 30,000 0 0
WAVELIFESCIENCESLTD SHS Y95308105 97,500 15,000 SH SOLE 15,000 0 0
ZEVRATHERAPEUTICSINC COMNEW 488445206 6,299,150 715,000 SH SOLE 715,000 0 0