Note 5 - Stockholders' Equity, Stock Option Plans, And Stock-Based Compensation - Stock-based Compensation Expense (Details) - USD ($) |
3 Months Ended | 6 Months Ended | ||
|---|---|---|---|---|
Jun. 30, 2025 |
Jun. 30, 2024 |
Jun. 30, 2025 |
Jun. 30, 2024 |
|
| Stock-based compensation expense | $ 395,277 | $ 358,993 | $ 1,314,396 | $ 728,068 |
| Research and Development Expense [Member] | ||||
| Stock-based compensation expense | 187,064 | 184,883 | 500,926 | 379,779 |
| General and Administrative Expense [Member] | ||||
| Stock-based compensation expense | $ 208,213 | $ 174,110 | $ 813,470 | $ 348,289 |