v3.25.2
Segments
 6 Months Ended
Jun. 30, 2025
Segments [Abstract]  
Segments
10. Segments
 
Operating segments are identified as components of an entity about which separate discrete financial information is available for evaluation by the CODM, or decision-making group, in making decisions on how to allocate resources and assess performance. The Company’s CODM, the Chief Executive Officer, views the Company’s operations as one operating segment, which is focused on creating new therapies for fibrotic disease based on targeting galectin proteins. The Company does not have revenue in the current comparative period, incurs expenses primarily in North America and manages the business activities on a consolidated basis.
 
The accounting policies of the fibrotic disease therapeutics segment are the same as those described in the summary of significant accounting policies.
 
The CODM assesses performance for the fibrotic disease therapeutics segment and decides how to allocate resources based on net loss that also is reported on the income statement as consolidated net loss. The measure of segment assets is reported on the balance sheet as cash and cash equivalents.
 
The Company has not generated any product revenue in the current period and expects to continue to incur significant expenses and operating losses for the foreseeable future as the Company advances its product candidates through all stages of development and clinical trials.
As such, the CODM uses cash forecast models in deciding how to invest into the fibrotic disease therapeutics segment. Such cash forecast models are reviewed to assess the entity-wide operating results and performance. Net loss is used to monitor budget versus actual results. Monitoring budgeted versus actual results, net cash used in operating activities for the period and cash on hand are used in assessing performance of the segment.
 
The table below summarizes the significant expense categories regularly reviewed by the CODM for the six month periods ended June 30, 2025 and 2024 (in thousands).
 
                 
    Six Months Ended
June 30, 		 
    2025     2024  
    (in thousands)  
Operating expenses:
           
Research and development
  $ 9,746     $ 17,867  
General and administrative
    2,776       3,072  
Total operating expenses
    12,522       20,939  
Total operating loss
    (12,522 )      (20,939 ) 
Other income (expense):
               
Interest income
    62       160  
Interest expense
    (3,570 )      (2,321 ) 
Change in fair value of derivatives
    (1,122 )      (760 ) 
Total other expense
    (4,630 )      (2,921 ) 
Net loss
  $ (17,152 )    $ (23,860 ) 
Preferred stock dividends
    (37 )     (72 ) 
Net loss applicable to common stockholders
  $ (17,180 )    $ (23,932 ) 
 
Other segment items included in segment loss includes interest income and interest expense.
 
The Company is a single operating segment and therefore the measure of segment net loss is the same as consolidated net loss and does not require reconciliation.
 
For the six month periods ended June 30, 2025 and 2024, the net cash used in operating activities was $14.3 million and $20.4 million, respectively. The table below summarizes the significant asset categories regularly reviewed by the CODM as of June 30, 2025 and December 31, 2024 (in thousands).
 
              
  June 30,
2025 		  December 31,
2024
  (in thousands)
Cash and cash equivalents
 $ 13,771    $ 15,120