v3.25.2
Document and Entity Information - shares
6 Months Ended
Jun. 30, 2025
Aug. 11, 2025
Document and Entity Information    
Document Type 10-Q  
Document Quarterly Report true  
Document Period End Date Jun. 30, 2025  
Document Transition Report false  
Entity File Number 001-38365  
Entity Registrant Name HYPERION DEFI, INC.  
Entity Incorporation, State or Country Code DE  
Entity Tax Identification Number 47-1178401  
Entity Address, Postal Zip Code 92653  
Entity Address, Address Line One 23461 S. Pointe Drive, Suite 390  
Entity Address, City or Town Laguna Hills  
Entity Address, State or Province CA  
City Area Code 833  
Local Phone Number 393-6684  
Title of 12(b) Security Common Stock, par value $0.0001 per share  
Trading Symbol HYPD  
Security Exchange Name NASDAQ  
Entity Current Reporting Status Yes  
Entity Interactive Data Current Yes  
Entity Filer Category Non-accelerated Filer  
Entity Small Business true  
Entity Emerging Growth Company false  
Entity Shell Company false  
Entity Common Stock, Shares Outstanding   5,694,659
Entity Central Index Key 0001682639  
Current Fiscal Year End Date --12-31  
Document Fiscal Year Focus 2025  
Document Fiscal Period Focus Q2  
Amendment Flag false