Stockholders' Equity - Company's Shares of Common Stock Reserved for Issuance (Detail) - shares	Jun. 30, 2025	Dec. 31, 2024
Class Of Warrant Or Right [Line Items]
Total shares reserved	60,933,040	61,932,290
April 2017 Warrants [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	24,725	24,725
June 2017 Warrants [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	41,736	41,736
December 2018 Warrants [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	11,332	11,332
Pre-Funded PIPE Warrants [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	5,780,537	5,780,537
2021 Pre-funded Warrants [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	32,175,172	32,175,172
2023 Pre-funded Warrants [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	5,666,667	5,666,667
Employee Stock Option
Class Of Warrant Or Right [Line Items]
Total shares reserved	13,189,871	13,554,621
Issued and nonvested RSUs [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	4,043,000	4,677,500